{"id":29073,"date":"2025-10-13T03:02:00","date_gmt":"2025-10-12T19:02:00","guid":{"rendered":"https:\/\/csccm.org.cn\/?p=29073"},"modified":"2025-10-13T12:42:48","modified_gmt":"2025-10-13T04:42:48","slug":"chest%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e4%bc%b4%e6%9c%89%e9%ab%98%e8%a1%80%e7%b3%96%e7%9a%84%e9%87%8d%e7%97%87%e6%82%a3%e8%80%85%e6%8c%81%e7%bb%ad%e8%a1%80%e7%b3%96%e7%9b%91%e6%b5%8b","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=29073","title":{"rendered":"[Chest\u53d1\u8868\u8bba\u6587]\uff1a\u4f34\u6709\u9ad8\u8840\u7cd6\u7684\u91cd\u75c7\u60a3\u8005\u6301\u7eed\u8840\u7cd6\u76d1\u6d4b"},"content":{"rendered":"\n<p><strong>CRITICAL CARE: ORIGINAL RESEARCH<\/strong><\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Continuous Glucose Monitoring for Hyperglycemia in Critically Ill Patients: A Randomized Controlled Trial<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Andrew J.\u00a0Franck,\u00a0Andrew L.\u00a0Hendrickson,\u00a0Evan D.\u00a0Telford,\u00a0et al<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\">Chest 2025; 168: 326-335<\/h3>\n\n\n\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Background<\/h3>\n\n\n\n<p>Continuous glucose monitors (CGMs) could potentially improve management of hyperglycemia compared with standard point-of-care glucose monitoring for critically ill patients. However, there is limited evidence to support routine use of CGMs in the ICU.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Research Question<\/h3>\n\n\n\n<p>In critically ill patients with hyperglycemia, do CGMs improve time within target glucose range compared with standard of care?<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Study Design and Methods<\/h3>\n\n\n\n<p>This was an investigator-initiated, single-center, parallel-group, open-label, randomized controlled trial. Adult patients admitted to a medical or surgical ICU who had diabetes mellitus or hyperglycemia and were treated with insulin were eligible for enrollment. Participants were randomly assigned to have glucose monitoring performed with a CGM (intervention group) or standard of care (control group). Groups were compared for glycemic control and other relevant outcomes. The primary outcome for the study was percentage of time within the normoglycemic range, defined as 70 to 180 mg\/dL (3.9-10 mmol\/L).<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Results<\/h3>\n\n\n\n<p>Eighty-five participants were enrolled and randomized to study groups, with 43 participants in the intervention (CGM) group and 42 patients in the control (standard of care) group. For the primary outcome, there was no statistically significant difference between the intervention group (mean \u00b1 SD, 60.5% \u00b1 30.5%) and the control group (mean \u00b1 SD, 61.4% \u00b1 28.3%) in time within the goal glucose range (mean difference, \u20130.9%; 95% CI, \u201313.6 to 11.8;\u00a0<em>P<\/em>\u00a0= .9). Except for patient satisfaction, there were no statistically significant differences between groups for secondary and exploratory outcomes.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/ga1_lrg.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"555\" src=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/ga1_lrg-1024x555.jpg\" alt=\"\" class=\"wp-image-29074\" srcset=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/ga1_lrg-1024x555.jpg 1024w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/ga1_lrg-300x163.jpg 300w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/ga1_lrg-768x416.jpg 768w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/ga1_lrg-1536x833.jpg 1536w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/ga1_lrg.jpg 1634w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/gr1_lrg.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"974\" height=\"1024\" src=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/gr1_lrg-974x1024.jpg\" alt=\"\" class=\"wp-image-29075\" srcset=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/gr1_lrg-974x1024.jpg 974w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/gr1_lrg-285x300.jpg 285w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/gr1_lrg-768x807.jpg 768w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/gr1_lrg-1461x1536.jpg 1461w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2025\/08\/gr1_lrg-1948x2048.jpg 1948w\" sizes=\"(max-width: 974px) 100vw, 974px\" \/><\/a><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Interpretation<\/h3>\n\n\n\n<p>The results of this study do not support CGMs as a superior method for routine glucose monitoring in the ICU compared with standard of care.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Clinical Trial Registration<\/h3>\n\n\n\n<p><a href=\"http:\/\/www.clinicaltrials.gov\/\" target=\"_blank\" rel=\"noreferrer noopener\">ClinicalTrials.gov<\/a>; No.: NCT05442853; URL:&nbsp;<a href=\"http:\/\/www.clinicaltrials.gov\/\" target=\"_blank\" rel=\"noreferrer noopener\">www.clinicaltrials.gov<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CRITICAL CARE: ORIGINAL RESEARCH Continuous Glucose Mon [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/29073"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=29073"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/29073\/revisions"}],"predecessor-version":[{"id":29076,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/29073\/revisions\/29076"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=29073"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=29073"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=29073"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}