{"id":28375,"date":"2025-07-10T04:07:00","date_gmt":"2025-07-09T20:07:00","guid":{"rendered":"https:\/\/csccm.org.cn\/?p=28375"},"modified":"2025-07-10T06:22:14","modified_gmt":"2025-07-09T22:22:14","slug":"jama-intern-med%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e5%8c%bb%e7%94%9f%e6%92%b0%e5%86%99%e4%b8%8e%e5%a4%a7%e5%9e%8b%e8%af%ad%e8%a8%80%e6%a8%a1%e5%9e%8b%e7%94%9f%e6%88%90%e7%9a%84%e5%87%ba","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=28375","title":{"rendered":"[JAMA Intern Med\u53d1\u8868\u8bba\u6587]\uff1a\u533b\u751f\u64b0\u5199\u4e0e\u5927\u578b\u8bed\u8a00\u6a21\u578b\u751f\u6210\u7684\u51fa\u9662\u8bb0\u5f55"},"content":{"rendered":"\n<p>Original Investigation&nbsp;<\/p>\n\n\n\n<p>May&nbsp;5,&nbsp;2025<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Physician- and Large Language Model\u2013Generated Hospital Discharge Summaries<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Christopher Y. K.&nbsp;Williams,&nbsp;Charumathi Raghu&nbsp;Subramanian,&nbsp;Syed Salman&nbsp;Ali,&nbsp;et al<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\"><em>JAMA Intern Med.&nbsp;<\/em>Published online May 5, 2025. doi:10.1001\/jamainternmed.2025.0821<\/h3>\n\n\n\n<p><a><\/a>Key Points<\/p>\n\n\n\n<p><strong>Question<\/strong>&nbsp;&nbsp;Can large language models (LLMs) draft hospital discharge summary narratives of comparable quality and safety to those written by physicians?<\/p>\n\n\n\n<p><strong>Findings<\/strong>&nbsp;&nbsp;In this cross-sectional study of 100 discharge summaries, there was no significant difference in LLM- and physician-generated narratives when rated by blinded reviewers on overall quality and preference. LLM-generated narratives were more concise and coherent than their physician-generated counterparts, but less comprehensive; LLM-generated narratives were also more likely to contain errors, but their overall potential for harm was low.<\/p>\n\n\n\n<p><strong>Meaning<\/strong>&nbsp;&nbsp;These findings suggest the potential for LLMs to aid clinicians by drafting discharge summary narratives.<a><\/a><\/p>\n\n\n\n<p>Abstract<\/p>\n\n\n\n<p><strong>Importance<\/strong>&nbsp;&nbsp;High-quality discharge summaries are associated with improved patient outcomes, but contribute to clinical documentation burden. Large language models (LLMs) provide an opportunity to support physicians by drafting discharge summary narratives.<\/p>\n\n\n\n<p><strong>Objective<\/strong>&nbsp;&nbsp;To determine whether LLM-generated discharge summary narratives are of comparable quality and safety to those of physicians.<\/p>\n\n\n\n<p><strong>Design, Setting, and Participants<\/strong>&nbsp;&nbsp;This cross-sectional study conducted at the University of California, San Francisco included 100 randomly selected inpatient hospital medicine encounters of 3 to 6 days\u2019 duration between 2019 and 2022. The analysis took place in July 2024.<\/p>\n\n\n\n<p><strong>Exposure<\/strong>&nbsp;&nbsp;A blinded evaluation of physician- and LLM-generated narratives was performed in duplicate by 22 attending physician reviewers.<\/p>\n\n\n\n<p><strong>Main Outcomes and Measures<\/strong>&nbsp;&nbsp;Narratives were reviewed for overall quality, reviewer preference, comprehensiveness, concision, coherence, and 3 error types (inaccuracies, omissions, and hallucinations). Each error individually, and each narrative overall, were assigned potential harmfulness scores ranging from 0 to 7 on an adapted Agency for Healthcare Research and Quality scale.<\/p>\n\n\n\n<p><strong>Results<\/strong>\u00a0\u00a0Across 100 encounters, LLM- and physician-generated narratives were comparable in overall quality on a Likert scale ranging from 1 to 5 (higher scores indicate higher quality; mean [SD] score, 3.67 [0.49] vs 3.77 [0.57];\u00a0<em>P<\/em>\u2009=\u2009.21) and reviewer preference (\u03c7<sup>2<\/sup>\u2009=\u20095.2;\u00a0<em>P<\/em>\u2009=\u2009.27). LLM-generated narratives were more concise (mean [SD] score, 4.01 [0.37] vs 3.70 [0.59];\u00a0<em>P<\/em>\u2009&lt;\u2009.001) and more coherent (mean [SD] score, 4.16 [0.39] vs 4.01 [0.53];\u00a0<em>P<\/em>\u2009=\u2009.02) than their physician-generated counterparts, but less comprehensive (mean [SD] score, 3.72 [0.58] vs 4.13 [0.58];\u00a0<em>P<\/em>\u2009&lt;\u2009.001). LLM-generated narratives contained more unique errors (mean [SD] errors per summary, 2.91 [2.54]) than physician-generated narratives (mean [SD] errors per summary, 1.82 [1.94]). There was no significant difference in the potential for harm between LLM- and physician-generated narratives across individual errors (mean [SD] of 1.35 [1.07] vs 1.34 [1.05];\u00a0<em>P<\/em>\u2009=\u2009.99), with 6 and 5 individual errors, respectively, with scores of 4 (potential for permanent harm) or greater. Both LLM- and physician-generated narratives had low overall potential for harm (scores &lt;1 on a scale ranging from 0-7), with LLM-generated narratives scoring higher than physician narratives (mean [SD] score of 0.84 [0.98] vs 0.36 [0.70];\u00a0<em>P<\/em>\u2009&lt;\u2009.001) and only 1 LLM-generated narrative (compared with 0 physician-generated narratives) scoring 4 or greater.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/intemed\/0\/ioi250018f1_1744989825.7585.png?Expires=1753802747&amp;Signature=j8Ct2U~Ovi~M~MP3xhD0aTt3~ePuyrTDAScegc74-LmUKK3y3TwJW36Jw8TYQASSApi9HfUfzarxMr40cAeSsVp9i137dCZy3xHer-mfhzTMyUA6KF8dYbQghGbqsdK-Wgsvnp9BJRs69cFb-LSBVyWfBGdpC6gIobgc8xhMCrQv9-JI78bkSdtdtrQSFf7uD802GqNBWEm9puNPvBFpxDtXha39EJPnTTnzybq6g~eTG7WdFYplRM0GvFeciA-q~WXm8WOi2m4gBaQtswdIV33he-T01ED-JsJQI2fWkxZlTYnyaFQjwlDmPMUa4IW3rP3fk547Xx-PBqNbrm-Mwg__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/intemed\/0\/ioi250018t1_1744989825.6885.png?Expires=1753802747&amp;Signature=fFMd9qNgHbKV2Ed54lK8PZaLiLcMhWCuf5gv105-ZbjZagTI7AkwKnPcSf~KFXxf8Qp6WXpXSZfdWU8C4xeZiLLBPXKYlFWkhEBsnLUs5whvZpuW-BcE0FAhXc39N1DC-lG9RoDun6Ieo-kY-Abb2c9OnsikH4exF-omMc7YFZACCSgKF2Hi0CGgQIYGzSSNgv9EIBAFG8YePrVapk2Jo8RD1IaPVuIMmuWOxV93OLaGK2eFjYC0RRi1ykewIzusdboKC2nUL16WykN-5SAkO5FzULDl~boToQrLqkIOnD0BiXYVBr6gywqEjcwrXpoFDvQDFLTk1jomkyFicjANTQ__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/intemed\/0\/ioi250018t2_1744989825.7735.png?Expires=1753802747&amp;Signature=IxWuU2l2CHaZCp1XvZry74eJNyMZj6zDscu4WeOC85km9QVI7ImPaekfe-MQF172znOLQ~SXPza7iZ15dlLqqOhmhTakpkQCQZhhNyvannL3tQdN2ZhGKA2HX1fOSq9x4~gMpUxBw08pdXTfM44x67xwJS554gvVD4J2L9upBuXGXlzFhSmhKPxHgkwhrqqDSuVkepG9agWXgDmL6wyub7aBvE4UcsM-phVruzbUHwvdXGyC7AJ-wq7m3fXGWvkyl8BeVGvWJJAJ2-xD7NePCfX9t43DOrHi32uhxe2~x0NIyEhTzPmlun9Hdun7OHsp81~Ng9qGbebyqT7Goo8mtQ__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/intemed\/0\/ioi250018t3_1744989825.7885.png?Expires=1753802747&amp;Signature=vlPhWbPMy3OKfH6V~EsH3aZPikpVCJy64ZRWPIqUtaCwu0TQNSIFTk1v1giFEMtku9e3dabG9p4tIHFL7o8tfIOdVfDzQGoElfD9Vq7QoOOQg-feO4UW21Xgnw7lw~99aPXgIkodIfoWAMgM-w5mfcEn4scJw1OgyvQ4iLoTO3cdrp53p-tFK1XmY~6dD2l7BEvU~krkrxoZE7NqI9cA7rWM0GCK4F3LFafHzoq9U3z3q7txyOtjPezPJnDFysVCQYIvBZK7CJzmfi3I6pCh7cwJVd2Qe7I74BDkmGwGPI~XPvNFHR2T8syJ4zte6U~vCN~N0q6NmS3IHihW~hF42g__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/intemed\/0\/ioi250018t4_1744989825.7935.png?Expires=1753802747&amp;Signature=eazy6-f8ce2CP~soU47PZn~P4owQVPGb8OgKgT~FEYsaLna10DLeTrTH~D-NAAuUm7r5bDi0c0HzUDJGt5V92UOkSNR8QLHGmfQazRNXFkM4FaC8wZvLkHvCy6oihoj7hFuW8QqYfSEsWwryLCcgJj6rrW~Z~hoMbfWWy60BtQBg3ZT4EFTgj2oy36Zv~bf8KpmoIZUDJFEeOsT~u8TQ-2I0YtGL1iPLAIs9qeWyG2y7I7R383efvKw6PCnQ41iraBKf-8pkBXeeRP-IlKnQhJY3Nqmc7LG~yojH3SrljgJWmdCtU7ZAM5JK5X2dl883XJ1F9m8oAzXQ40LOkkRLVA__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<p><strong>Conclusions and Relevance<\/strong>&nbsp;&nbsp;In this cross-sectional study of 100 inpatient hospital medicine encounters, LLM-generated discharge summary narratives were of comparable quality, and were preferred equally, to those generated by physicians. LLM-generated narratives were more likely to contain errors but had low overall harmfulness scores. These results suggest that, in clinical practice, using such narratives after human review may provide a viable option for hospitalists.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Original Investigation&nbsp; May&nbsp;5,&nbsp;2025 Phys [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/28375"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=28375"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/28375\/revisions"}],"predecessor-version":[{"id":28693,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/28375\/revisions\/28693"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=28375"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=28375"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=28375"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}