{"id":28347,"date":"2025-07-05T04:54:00","date_gmt":"2025-07-04T20:54:00","guid":{"rendered":"https:\/\/csccm.org.cn\/?p=28347"},"modified":"2025-07-05T06:16:03","modified_gmt":"2025-07-04T22:16:03","slug":"lancet-infect-dis%e5%8f%91%e5%b8%83%e6%8c%87%e5%8d%97%ef%bc%9a%e5%bf%b5%e7%8f%a0%e8%8f%8c%e7%97%85%e7%9a%84%e8%af%8a%e6%96%ad%e4%b8%8e%e6%b2%bb%e7%96%97%e5%85%a8%e7%90%83%e6%8c%87%e5%8d%97","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=28347","title":{"rendered":"[Lancet Infect Dis\u53d1\u5e03\u6307\u5357]\uff1a\u5ff5\u73e0\u83cc\u75c5\u7684\u8bca\u65ad\u4e0e\u6cbb\u7597\u5168\u7403\u6307\u5357"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\" id=\"screen-reader-main-title\">Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Oliver A\u00a0Cornely,\u00a0Rosanne\u00a0Sprute,\u00a0Matteo\u00a0Bassetti, et al<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\">Lancet Infect Dis 2025; 25: e280-e293<\/h3>\n\n\n\n<h2 class=\"wp-block-heading\">Summary<\/h2>\n\n\n\n<p><em>Candida<\/em>\u00a0species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who are immunocompromised or critically ill. In contrast, mucocutaneous forms of candidiasis, such as oral thrush and vulvovaginal candidiasis, can occur in otherwise healthy individuals. Although mucocutaneous candidiasis is generally not life-threatening, it can cause considerable discomfort, recurrent infections, and complications, particularly in patients with underlying conditions such as diabetes or in those taking immunosuppressive therapies. The rise of difficult-to-treat\u00a0<em>Candida<\/em>\u00a0infections is driven by new host factors and antifungal resistance. Pathogens, such as\u00a0<em>Candida auris<\/em>\u00a0(<em>Candidozyma auris<\/em>) and fluconazole-resistant\u00a0<em>Candida parapsilosis<\/em>, pose serious global health risks. Recent taxonomic revisions have reclassified several\u00a0<em>Candida<\/em>\u00a0spp, potentially causing confusion in clinical practice. Current management guidelines are limited in scope, with poor coverage of emerging pathogens and new treatment options. In this Review, we provide updated recommendations for managing\u00a0<em>Candida<\/em>\u00a0infections, with detailed evidence summaries available in the appendix.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S1473309924007497-gr1_lrg.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S1473309924007497-gr2_lrg.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S1473309924007497-gr3_lrg.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S1473309924007497-gr4_lrg.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/ars.els-cdn.com\/content\/image\/1-s2.0-S1473309924007497-gr5_lrg.jpg\" alt=\"\"\/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Global guideline for the diagnosis and management of ca [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[25,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/28347"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=28347"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/28347\/revisions"}],"predecessor-version":[{"id":28348,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/28347\/revisions\/28348"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=28347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=28347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=28347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}