{"id":27353,"date":"2025-02-12T04:52:00","date_gmt":"2025-02-11T20:52:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=27353"},"modified":"2025-02-12T05:57:15","modified_gmt":"2025-02-11T21:57:15","slug":"clin-infect-dis%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e9%9d%9e%e5%91%bc%e5%90%b8%e6%9c%ba%e7%9b%b8%e5%85%b3%e7%9a%84%e5%8c%bb%e9%99%a2%e8%8e%b7%e5%be%97%e6%80%a7%e8%82%ba%e7%82%8e%e6%82%a3","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=27353","title":{"rendered":"[Clin Infect Dis\u53d1\u8868\u8bba\u6587]\uff1a\u975e\u547c\u5438\u673a\u76f8\u5173\u7684\u533b\u9662\u83b7\u5f97\u6027\u80ba\u708e\u60a3\u8005\u9662\u5185\u6b7b\u4ea1\u7684\u53ef\u9884\u9632\u6027"},"content":{"rendered":"\n

JOURNAL ARTICLE<\/p>\n\n\n\n

Preventability of Hospital Deaths in Patients With Non-Ventilator Hospital-Acquired Pneumonia<\/h1>\n\n\n\n

Alexander M Tatara,  Anna Apostolopoulou,  Anna A Agan,  et al<\/h3>\n\n\n\n

Clinical Infectious Diseases<\/em> 2024; 79: 1269-1276<\/h3>\n\n\n\n

https:\/\/doi.org\/10.1093\/cid\/ciae418<\/a><\/h3>\n\n\n\n

Abstract<\/h2>\n\n\n\n

Background<\/p>\n\n\n\n

Crude and adjusted mortality rates for patients with non-ventilator hospital-acquired pneumonia (NV-HAP) are among the highest of all healthcare-associated infections, leading to calls for greater prevention. Patients prone to NV-HAP, however, tend to be severely ill at baseline, making it unclear whether their high mortality rates are due to NV-HAP, their underlying conditions, or both.<\/p>\n\n\n\n

Methods<\/p>\n\n\n\n

Two infectious disease physicians conducted detailed medical record reviews on 150 randomly selected adults from 4 hospitals who died in-hospital following an NV-HAP event between April 2016 and May 2021. Reviewers abstracted risk factors, estimated the preventability of NV-HAP, identified causes of death, and adjudicated the preventability of death.<\/p>\n\n\n\n

Results<\/p>\n\n\n\n

The patients\u2019 median age was 69.3 (IQR, 60.7\u201377.4) years and 43.3% were female. Comorbidities were common: 57% had cancer, 30% chronic kidney disease, 29% chronic lung disease, and 27% had heart failure. At least 1 hospice-eligible condition was present before NV-HAP in 54% and \u201cDo Not Resuscitate\u201d orders in 24%. Most (99%) had difficult-to-modify NV-HAP risk factors: 76% altered mental status, 35% dysphagia, and 27% nasogastric\/orogastric tubes. NV-HAP was deemed possibly or probably preventable in 21% and hospital death likely or very likely preventable in 8.6%.<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

Conclusions<\/p>\n\n\n\n

Most patients who die following NV-HAP have multiple, severe underlying comorbidities and difficult-to-modify risk factors for NV-HAP. Only 1 in 5 NV-HAPs that culminated in death and 1 in 12 deaths following NV-HAP were judged potentially preventable. This does not diminish the importance of NV-HAP prevention programs but informs expectations about the potential magnitude of their impact on hospital deaths.<\/p>\n","protected":false},"excerpt":{"rendered":"

JOURNAL ARTICLE Preventability of Hospital Deaths in Pa […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/27353"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27353"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/27353\/revisions"}],"predecessor-version":[{"id":27708,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/27353\/revisions\/27708"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27353"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27353"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27353"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}