{"id":26992,"date":"2024-10-15T04:54:00","date_gmt":"2024-10-14T20:54:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=26992"},"modified":"2024-10-15T05:39:52","modified_gmt":"2024-10-14T21:39:52","slug":"jama%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e8%bf%9c%e7%a8%8bicu%e5%af%b9%e9%87%8d%e7%97%87%e6%82%a3%e8%80%85%e4%b8%b4%e5%ba%8a%e9%a2%84%e5%90%8e%e7%9a%84%e5%bd%b1%e5%93%8d","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=26992","title":{"rendered":"[JAMA\u53d1\u8868\u8bba\u6587]\uff1a\u8fdc\u7a0bICU\u5bf9\u91cd\u75c7\u60a3\u8005\u4e34\u5e8a\u9884\u540e\u7684\u5f71\u54cd"},"content":{"rendered":"\n<p>Original Investigation\u00a0| Caring for the Critically Ill Patient<\/p>\n\n\n\n<p>October&nbsp;9,&nbsp;2024<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients: The TELESCOPE Randomized Clinical Trial<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Adriano J.\u00a0Pereira,\u00a0Danilo T.\u00a0Noritomi,\u00a0Maura Cristina\u00a0dos Santos,\u00a0et al<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\"><em>JAMA.\u00a0<\/em>Published online October 9, 2024. doi:10.1001\/jama.2024.20651<\/h3>\n\n\n\n<p><a rel=\"noreferrer noopener\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/pages\/jama-author-interviews\" target=\"_blank\"><\/a>Key Points<\/p>\n\n\n\n<p><strong>Question<\/strong>&nbsp;&nbsp;Is an intensivist-led telemedicine-based strategy including daily multidisciplinary rounds combined with monthly audit and feedback able to reduce intensive care unit (ICU) length of stay compared with usual care?<\/p>\n\n\n\n<p><strong>Findings<\/strong>&nbsp;&nbsp;In a cluster randomized clinical trial of 30 ICUs (n\u2009=\u200915\u202f230 patients in the intervention period), multidisciplinary rounds and monthly audit and feedback meetings performed by remote intensivists (tele-ICU) did not significantly reduce the ICU length of stay compared with the standard care group.<\/p>\n\n\n\n<p><strong>Meaning<\/strong>&nbsp;&nbsp;An intervention comprising daily multidisciplinary rounds and monthly audit and feedback meetings performed by board-certified remote intensivists (tele-ICU) had no impact on ICU length of stay.<a><\/a><\/p>\n\n\n\n<p>Abstract<\/p>\n\n\n\n<p><strong>Importance<\/strong>&nbsp;&nbsp;Despite its implementation in several countries, there has not been a randomized clinical trial to assess whether telemedicine in intensive care units (ICUs) could improve clinical outcomes of critically ill patients.<\/p>\n\n\n\n<p><strong>Objective<\/strong>&nbsp;&nbsp;To determine whether an intervention comprising daily multidisciplinary rounds and monthly audit and feedback meetings performed by a remote board-certified intensivist reduces ICU length of stay (LOS) compared with usual care.<\/p>\n\n\n\n<p><strong>Design, Setting, and Participants<\/strong>&nbsp;&nbsp;A parallel cluster randomized clinical trial with a baseline period in 30 general ICUs in Brazil in which daily multidisciplinary rounds performed by board-certified intensivists were not routinely available. All consecutive adult patients (aged \u226518 years) admitted to the participating ICUs, excluding those admitted due to justice-related issues, were enrolled between June 1, 2019, and April 7, 2021, with last follow-up on July 6, 2021.<\/p>\n\n\n\n<p><strong>Intervention<\/strong>&nbsp;&nbsp;Remote daily multidisciplinary rounds led by a board-certified intensivist through telemedicine, monthly audit and feedback meetings for discussion of ICU performance indicators, and provision of evidence-based clinical protocols.<\/p>\n\n\n\n<p><strong>Main Outcomes and Measures<\/strong>&nbsp;&nbsp;The primary outcome was ICU LOS at the patient level. Secondary outcomes included ICU efficiency, in-hospital mortality, incidence of central line\u2013associated bloodstream infections, ventilator-associated events, catheter-associated urinary tract infections, ventilator-free days at 28 days, patient-days receiving oral or enteral feeding, patient-days under light sedation, and rate of patients with oxygen saturation values under that of normoxemia, assessed using generalized linear mixed models.<\/p>\n\n\n\n<p><strong>Results<\/strong>\u00a0\u00a0Among 17\u202f024 patients (1794 in the baseline period and 15\u202f230 in the intervention period), the mean (SD) age was 61 (18) years, 44.7% were female, the median (IQR) Sequential Organ Failure Assessment score was 6 (2-9), and 45.5% were invasively mechanically ventilated at admission. The median (IQR) time under intervention was 20 (16-21) months. Mean (SD) ICU LOS, adjusted for baseline assessment, did not differ significantly between the tele\u2013critical care and usual care groups (8.1 [10.0] and 7.1 [9.0] days; percentage change, 8.2% [95% CI, \u22125.4% to 23.8%];\u00a0<em>P<\/em>\u2009=\u2009.24). Results were similar in sensitivity analyses and prespecified subgroups. There were no statistically significant differences in any other secondary or exploratory outcomes.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/jama\/0\/joi240117f1_1728315005.24996.png?Expires=1731534290&amp;Signature=RhmpBEsP7xIeK6IL0rjpSYczGA9leumZvaXaaLHAxfl-~mANtQ65Cfsa0iGdyC4B5zweC3zUqgO9EAAUP2VPSVp2hqaavWTyxd-l2DLRiqFK~PNNeoNIoYL9vYU-eGnvJBEF~TPuyROdQ3LBPfggaL6q28rFrpRIGUuD6b4LBGL-TGMeJao7LHFbNQ5gOrgYXjZP8QvSrXGity7N9bh9vFBv68qgPynUhsrx80CHmJPUHBYwZyH5mGcKr2~zdElW0sk4EUifQ9Fdp4-qzjApoz73~JUZ3fTViy9-Cfjym6Rf-NzQAft5Y5dDRZ1MVzoAY9HZP1QG2aRlJyThIbZeUg__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/jama\/0\/joi240117f2_1728315005.29.png?Expires=1731534290&amp;Signature=hQnvOzmxuf9fjKxMqgTIEWLOCqSu3WD94x8FF14aWzDHjUSZjqpNmN6TWKXeBg8ZqOydwo1YP6m40UNyUPRlwBQLqNEBWSjKfor5cP9cCF5a4Z4WIU-MlDpVrXhw37ipaGayussmye6YOjgbczZRdk2uQL~V~WsIT-UDDYfthPIyAVfz0X2KG~Q6Vg~n4gAfqMP~j8og0jF12tbluvvsTZRVrECvyd35Y1Kw4l01p4Jw5XEjHpEVlAcGR3rV5vxEKAkRCDptwU6Q6EH-FJiPMebj7cdFFy38x9DwTA5PFhK3uky1hTB1ODJ5xOREdvWG9ax6QXXKdy9xoJzpFTMydg__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/jama\/0\/joi240117t1_1728315005.21927.png?Expires=1731534290&amp;Signature=bp7MfEp~CGTmLC~cJIXZHNGnjw6udttJsGVU50dV3avet9HWynIw-ZxzqlSVXCeXebYX3OfAu7uLrMNHmSWcYTgoDdhKJs3xuFYc1GujzgimqnSHnFKAoBNQq2n9WxLTATTJjKp2TOnqojxM1pYTqMHdI2nKuZzV4lSiepcHPuV1TNwS8ueSCp5xtisUdzyTvCjMOapjrH79GIvmW3PYAbx43Odq5QwktsDgIAJDIX2XqBcF-XqXXejft49niBpEeWHSS6sPYLJJK-BImNURCeG0AjG71q-fU0KM38zSJ-RN2dmNQDonwNPvIzp3ASGZN~0K7QXO8EIfvi1gxQuvzw__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/jama\/0\/joi240117t2_1728315005.27997.png?Expires=1731534290&amp;Signature=xqcatrMH0St~lVZ94bxf7SVl8mPQ5pSKvDYuqGECTJBTj1LMscR4pfwXpc8t0FN5vlP60t0XedBV8SHQ~yGlkCk3lbpaakFIsPJHnOKxB2jyneyazuwotDHki6uqKrrJGhF~qV4litIf1rMV0qAcudfEjj2TZBGNdxjIZL9Zn~jtWrpbf5tol2zpwrR214j5eiBXB-ZWGzJLNKtgO~ER-vJakzEjCCXVfhZTrPcDv1ZeqXpUx9tl8-CERY12r1WVZFIHgHivNGOjP~8ZUxkSoaSCd237dUnRZnW-1qmpCcWi3d4BaqouYTjck8-g7srAdZuhsdF18WAgzbZZDa1Lpg__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/jama\/0\/joi240117t3_1728315005.30501.png?Expires=1731534290&amp;Signature=4tToAshgv70yT4nI4T8lzuxIsAU12SFuuWOUKzQBLyY4cgOsrV~DYy002qLb1fnC0ZdXuMjP9RHSfTLSn~XO5q1IDiQVmJ7NUXMaiHGIbyM~~4rvGRZcuxkadNBN6VinQyNsJEBY84oKy6lh7PZObMToaK-Eev2AB8kq7N6YOH7qj-kdSIC3Gp6zeeNb4bKA7aigXFFM05d1qSFoZE9T1e4SJfZ5BSCeU89~726V59-O~Gz9plF99Y1dBxJ0R~FP969HGbmXQtigKWeCtKbtFTDnmx-pPkoTa18GYnLfcMrV~QCxAQ8R9AojgXLIXHEIW6IYlDSuX1~NjOvBHY2MQg__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n\n\n\n<p><strong>Conclusions and Relevance<\/strong>&nbsp;&nbsp;Daily multidisciplinary rounds conducted by a board-certified intensivist through telemedicine did not reduce ICU LOS in critically ill adult patients.<\/p>\n\n\n\n<p><strong>Trial Registration<\/strong>&nbsp;&nbsp;ClinicalTrials.gov Identifier:&nbsp;<a href=\"https:\/\/clinicaltrials.gov\/study\/NCT03920501\">NCT03920501<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Original Investigation\u00a0| Caring for the Critically Ill  [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/26992"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26992"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/26992\/revisions"}],"predecessor-version":[{"id":26993,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/26992\/revisions\/26993"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26992"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26992"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26992"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}