{"id":26715,"date":"2024-10-31T04:10:00","date_gmt":"2024-10-30T20:10:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=26715"},"modified":"2024-10-31T05:55:35","modified_gmt":"2024-10-30T21:55:35","slug":"lancet-respir-med%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a2020%e5%b9%b412%e6%9c%88%e8%87%b32023%e5%b9%b43%e6%9c%88%e9%97%b4who%e6%ac%a7%e6%b4%b2%e5%8c%ba%e6%96%b0%e5%86%a0%e7%97%85%e6%af%92","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=26715","title":{"rendered":"[Lancet Respir Med\u53d1\u8868\u8bba\u6587]\uff1a2020\u5e7412\u6708\u81f32023\u5e743\u6708\u95f4WHO\u6b27\u6d32\u533a\u65b0\u51a0\u75c5\u6bd2\u75ab\u82d7\u9879\u76ee\u76f4\u63a5\u633d\u6551\u7684\u4eba\u6570\u4f30\u8ba1"},"content":{"rendered":"\n

ARTICLES<\/strong>Volume 12, Issue 9<\/a>P714-727September 2024<\/p>\n\n\n\n

Estimated number of lives directly saved by COVID-19 vaccination programmes in the WHO European Region from December, 2020, to March, 2023: a retrospective surveillance study<\/h1>\n\n\n\n

Margaux M I Mesl\u00e9, Jeremy Brown, Piers Mook, et al<\/h3>\n\n\n\n

Lancet Respir Med 2024; 12: 714-727<\/h3>\n\n\n\n

Summary<\/h2>\n\n\n\n

Background<\/h3>\n\n\n\n

By March, 2023, 54 countries, areas, and territories (hereafter CAT) in the WHO European Region had reported more than 2\u00b72 million COVID-19-related deaths to the WHO Regional Office for Europe. Here, we estimated how many lives were directly saved by vaccinating adults in the WHO European Region from December, 2020, to March, 2023.<\/p>\n\n\n\n

Methods<\/h3>\n\n\n\n

In this retrospective surveillance study, we estimated the number of lives directly saved by age group, vaccine dose, and circulating variant-of-concern (VOC) period, regionally and nationally, using weekly data on COVID-19 mortality and infection, COVID-19 vaccination uptake, and SARS-CoV-2 virus characterisations by lineage downloaded from The European Surveillance System on June 11, 2023, as well as vaccine effectiveness data from the literature. We included data for six age groups (25\u201349 years, 50\u201359 years, \u226560 years, 60\u201369 years, 70\u201379 years, and \u226580 years). To be included in the analysis, CAT needed to have reported both COVID-19 vaccination and mortality data for at least one of the four older age groups. Only CAT that reported weekly data for both COVID-19 vaccination and mortality by age group for 90% of study weeks or more in the full study period were included. We calculated the percentage reduction in the number of expected and reported deaths.<\/p>\n\n\n\n

Findings<\/h3>\n\n\n\n

Between December, 2020, and March, 2023, in 34 of 54 CAT included in the analysis, COVID-19 vaccines reduced deaths by 59% overall (CAT range 17\u201382%), representing approximately 1\u00b76 million lives saved (range 1\u00b75\u20131\u00b77 million) in those aged 25 years or older: 96% of lives saved were aged 60 years or older and 52% were aged 80 years or older; first boosters saved 51% of lives, and 60% were saved during the Omicron period.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n
\"\"<\/a><\/figure>\n\n\n\n

Interpretation<\/h3>\n\n\n\n

Over nearly 2\u00b75 years, most lives saved by COVID-19 vaccination were in older adults by first booster dose and during the Omicron period, reinforcing the importance of up-to-date vaccination among the most at-risk individuals. Further modelling work should evaluate indirect effects of vaccination and public health and social measures.<\/p>\n\n\n\n

Funding<\/h3>\n\n\n\n

US Centers for Disease Control and Prevention.<\/p>\n","protected":false},"excerpt":{"rendered":"

ARTICLESVolume 12, Issue 9P714-727September 2024 E […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/26715"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26715"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/26715\/revisions"}],"predecessor-version":[{"id":26942,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/26715\/revisions\/26942"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26715"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26715"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}