{"id":25533,"date":"2024-04-05T04:38:00","date_gmt":"2024-04-04T20:38:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=25533"},"modified":"2024-04-05T06:39:35","modified_gmt":"2024-04-04T22:39:35","slug":"bmj%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e5%bf%83%e8%82%ba%e5%a4%8d%e8%8b%8f%e6%97%b6%e9%95%bf%e4%b8%8e%e9%99%a2%e5%86%85%e5%bf%83%e8%b7%b3%e9%aa%a4%e5%81%9c%e6%88%90%e5%b9%b4%e6%82%a3","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=25533","title":{"rendered":"[BMJ\u53d1\u8868\u8bba\u6587]\uff1a\u5fc3\u80ba\u590d\u82cf\u65f6\u957f\u4e0e\u9662\u5185\u5fc3\u8df3\u9aa4\u505c\u6210\u5e74\u60a3\u8005\u7684\u4e34\u5e8a\u7ed3\u5c40"},"content":{"rendered":"\n

Research<\/strong><\/p>\n\n\n\n

Duration of cardiopulmonary resuscitation and outcomes for adults with in-hospital cardiac arrest: retrospective cohort study<\/h1>\n\n\n\n

Masashi Okubo<\/a>, Sho Komukai, Lars W Andersen,\u00a0et al<\/h3>\n\n\n\n

BMJ<\/em>\u00a02024;\u00a0384\u00a0doi:\u00a0https:\/\/doi.org\/10.1136\/bmj-2023-076019<\/a>\u00a0(Published 07 February 2024)Cite this as:\u00a0BMJ<\/em>\u00a02024;384:e076019<\/h3>\n\n\n\n

Abstract<\/h2>\n\n\n\n

Objective<\/strong> To quantify time dependent probabilities of outcomes in patients after in-hospital cardiac arrest as a function of duration of cardiopulmonary resuscitation, defined as the interval between start of chest compression and the first return of spontaneous circulation or termination of resuscitation.<\/p>\n\n\n\n

Design<\/strong> Retrospective cohort study.<\/p>\n\n\n\n

Setting<\/strong> Multicenter prospective in-hospital cardiac arrest registry in the United States.<\/p>\n\n\n\n

Participants<\/strong> 348\u2009996 adult patients (\u226518 years) with an index in-hospital cardiac arrest who received cardiopulmonary resuscitation from 2000 through 2021.<\/p>\n\n\n\n

Main outcome measures<\/strong> Survival to hospital discharge and favorable functional outcome at hospital discharge, defined as a cerebral performance category score of 1 (good cerebral performance) or 2 (moderate cerebral disability). Time dependent probabilities of subsequently surviving to hospital discharge or having favorable functional outcome if patients pending the first return of spontaneous circulation at each minute received further cardiopulmonary resuscitation beyond the time point were estimated, assuming that all decisions on termination of resuscitation were accurate (that is, all patients with termination of resuscitation would have invariably failed to survive if cardiopulmonary resuscitation had continued for a longer period of time).<\/p>\n\n\n\n

Results<\/strong>\u00a0Among 348\u2009996 included patients, 233\u2009551 (66.9%) achieved return of spontaneous circulation with a median interval of 7 (interquartile range 3-13) minutes between start of chest compressions and first return of spontaneous circulation, whereas 115\u2009445 (33.1%) patients did not achieve return of spontaneous circulation with a median interval of 20 (14-30) minutes between start of chest compressions and termination of resuscitation. 78\u2009799 (22.6%) patients survived to hospital discharge. The time dependent probabilities of survival and favorable functional outcome among patients pending return of spontaneous circulation at one minute\u2019s duration of cardiopulmonary resuscitation were 22.0% (75\u2009645\/343\u2009866) and 15.1% (49\u2009769\/328\u2009771), respectively. The probabilities decreased over time and were <1% for survival at 39 minutes and <1% for favorable functional outcome at 32 minutes\u2019 duration of cardiopulmonary resuscitation.<\/p>\n\n\n\n

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Conclusions<\/strong> This analysis of a large multicenter registry of in-hospital cardiac arrest quantified the time dependent probabilities of patients\u2019 outcomes in each minute of duration of cardiopulmonary resuscitation. The findings provide resuscitation teams, patients, and their surrogates with insights into the likelihood of favorable outcomes if patients pending the first return of spontaneous circulation continue to receive further cardiopulmonary resuscitation.<\/p>\n","protected":false},"excerpt":{"rendered":"

Research Duration of cardiopulmonary resuscitation and […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/25533"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25533"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/25533\/revisions"}],"predecessor-version":[{"id":25534,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/25533\/revisions\/25534"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25533"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25533"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25533"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}