{"id":25092,"date":"2024-01-15T04:44:00","date_gmt":"2024-01-14T20:44:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=25092"},"modified":"2024-01-15T05:38:20","modified_gmt":"2024-01-14T21:38:20","slug":"nejm%e4%b8%b4%e5%ba%8a%e5%8c%bb%e5%ad%a6%e5%bd%b1%e5%83%8f%ef%bc%9a%e6%a8%aa%e5%90%91%e7%99%bd%e7%94%b2%e7%97%87%ef%bc%88%e7%b1%b3%e6%b0%8f%e7%ba%bf%ef%bc%89","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=25092","title":{"rendered":"[NEJM\u4e34\u5e8a\u533b\u5b66\u5f71\u50cf]\uff1a\u6a2a\u5411\u767d\u7532\u75c7\uff08\u7c73\u6c0f\u7ebf\uff09"},"content":{"rendered":"\n<p><a href=\"https:\/\/www.nejm.org\/multimedia\/images-in-clinical-medicine\" class=\"\">IMAGES IN CLINICAL MEDICINE<\/a><\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Transverse Leukonychia (Mees\u2019 Lines)<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Annabel M. Follows, George A. Follows<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\">N Engl J Med 2023; 389:e48<br \/>DOI: 10.1056\/NEJMicm2304533<\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/www.nejm.org\/na101\/home\/literatum\/publisher\/mms\/journals\/content\/nejm\/2023\/nejm_2023.389.issue-22\/nejmicm2304533\/20231127\/images\/img_large\/nejmicm2304533_f1.jpeg\" alt=\"\"\/><\/figure>\n\n\n\n<p>A 30-year-old man presented to the hematology clinic with a 4-month history of white lines across his fingernails. Five months before presentation, he had received a diagnosis of primary mediastinal large B-cell lymphoma and began to receive systemic chemotherapy. The nail changes had first appeared midway through his six cycles of treatment. Physical examination was notable for six transverse white lines that were visible on the nails on both hands. A diagnosis of transverse leukonychia \u2014 also known as Mees\u2019 lines \u2014 was made. Mees\u2019 lines occur when there is abnormal keratinization of the distal nail matrix. In this case, each of the patient\u2019s six chemotherapy cycles was thought to correspond to a band of leukonychia. Mees\u2019 lines can be differentiated from Muehrcke\u2019s lines \u2014 a type of apparent leukonychia triggered by vascular changes to the nail bed \u2014 because Mees\u2019 lines do not blanch. Mees\u2019 lines are also smooth, which differentiates them from Beau\u2019s lines (transverse depressions in the nail bed owing to an arrest of nail matrix growth). The patient was reassured about the benign nature of the nail changes. At the 10-month follow-up, the nail changes had resolved.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>IMAGES IN CLINICAL MEDICINE Transverse Leukonychia (Mee [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[16,13],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/25092"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25092"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/25092\/revisions"}],"predecessor-version":[{"id":25093,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/25092\/revisions\/25093"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25092"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25092"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25092"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}