{"id":24720,"date":"2023-12-05T04:30:00","date_gmt":"2023-12-04T20:30:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=24720"},"modified":"2023-12-05T05:43:09","modified_gmt":"2023-12-04T21:43:09","slug":"cid%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e4%b8%8d%e8%b6%b32%e5%b2%81%e5%84%bf%e7%ab%a5%e5%91%bc%e5%90%b8%e9%81%93%e7%97%85%e6%af%92%e6%84%9f%e6%9f%93%e7%9a%84%e7%96%be%e7%97%85%e8%b4%9f","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=24720","title":{"rendered":"[CID\u53d1\u8868\u8bba\u6587]\uff1a\u4e0d\u8db32\u5c81\u513f\u7ae5\u547c\u5438\u9053\u75c5\u6bd2\u611f\u67d3\u7684\u75be\u75c5\u8d1f\u62c5"},"content":{"rendered":"\n

JOURNAL ARTICLE<\/p>\n\n\n\n

Burden of Respiratory Viruses in Children Less Than 2 Years Old in a Community-based Longitudinal US Birth Cohort\u00a0<\/h1>\n\n\n\n

Zheyi Teoh,\u00a0\u00a0Shannon Conrey,\u00a0\u00a0Monica McNeal,\u00a0\u00a0et al<\/h3>\n\n\n\n

Clinical Infectious Diseases<\/em>, Volume 77, Issue 6, 15 September 2023, Pages 901\u2013909<\/h3>\n\n\n\n

https:\/\/doi.org\/10.1093\/cid\/ciad289<\/a><\/h3>\n\n\n\n

Abstract<\/h2>\n\n\n\n

Background<\/p>\n\n\n\n

Respiratory viral infections are a major cause of morbidity and hospitalization in young children. Nevertheless, the population burden of respiratory viral infections, especially asymptomatic cases, is not known due to the lack of prospective community-based cohort studies with intensive monitoring.<\/p>\n\n\n\n

Methods<\/p>\n\n\n\n

To address this gap, we enacted the PREVAIL cohort, a Centers for Disease Control and Prevention\u2013sponsored birth cohort in Cincinnati, Ohio, where children were followed from 0 to 2 years of age. Weekly text surveys were administered to record acute respiratory illnesses (ARIs), which were defined as the presence of cough or fever (\u226538\u00b0C). Weekly midturbinate nasal swabs were collected and tested using the Luminex Respiratory Pathogen Panel, which detected 16 viral pathogens. Viral infection was defined as \u22651 positive tests from the same virus or viral subtype \u226430 days of a previous positive test. Maternal report and medical chart abstractions identified healthcare utilization.<\/p>\n\n\n\n

Results<\/p>\n\n\n\n

From 4\/2017 to 7\/2020, 245 mother\u2013infant pairs were recruited and followed. From the 13 781 nasal swabs tested, a total of 2211 viral infections were detected, of which 821 (37%) were symptomatic. Children experienced 9.4 respiratory viral infections\/child-year; half were rhinovirus\/enterovirus. Viral ARI incidence was 3.3 episodes\/child-year. Emergency department visits or hospitalization occurred with only 15% of respiratory syncytial virus infections, 10% of influenza infections, and only 4% of all viral infections. Regardless of\u00a0pathogen, most infections were asymptomatic or mild.<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

Conclusions<\/p>\n\n\n\n

Respiratory viral infections are common in children 0\u20132 years. Most viral infections are asymptomatic or non\u2013medically attended, underscoring the importance of community-based cohort studies.<\/p>\n","protected":false},"excerpt":{"rendered":"

JOURNAL ARTICLE Burden of Respiratory Viruses in Childr […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/24720"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24720"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/24720\/revisions"}],"predecessor-version":[{"id":25098,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/24720\/revisions\/25098"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24720"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24720"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}