{"id":24584,"date":"2023-10-01T04:54:00","date_gmt":"2023-09-30T20:54:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=24584"},"modified":"2023-10-01T06:28:36","modified_gmt":"2023-09-30T22:28:36","slug":"jama%e8%af%8a%e6%96%ad%e6%a3%80%e6%9f%a5%e8%a7%a3%e8%af%bb%ef%bc%9a%e9%9a%be%e8%be%a8%e6%a2%ad%e7%8a%b6%e8%8a%bd%e5%ad%a2%e6%9d%86%e8%8f%8c%e6%84%9f%e6%9f%93%e7%9a%84%e5%a4%9a%e9%87%8d%e6%a3%80","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=24584","title":{"rendered":"[JAMA\u8bca\u65ad\u68c0\u67e5\u89e3\u8bfb]\uff1a\u96be\u8fa8\u68ad\u72b6\u82bd\u5b62\u6746\u83cc\u611f\u67d3\u7684\u591a\u91cd\u68c0\u67e5\u6b65\u9aa4\uff08\u95ee\u9898\uff09"},"content":{"rendered":"\n

JAMA Diagnostic Test Interpretation <\/p>\n\n\n\n

August 21, 2023<\/p>\n\n\n\n

Multistep Testing Algorithms for Clostridioides difficile<\/em> Infection<\/h1>\n\n\n\n

Maribeth R.\u00a0Nicholson,\u00a0Curtis J.\u00a0Donskey<\/h3>\n\n\n\n

JAMA.\u00a0<\/em>Published online August 21, 2023. doi:10.1001\/jama.2023.15875<\/h3>\n\n\n\n

Case<\/p>\n\n\n\n

A10-year-old female with spina bifida and neurogenic bowel was hospitalized for abdominal pain, dehydration, and more than 20 episodes of watery diarrhea per day. Her symptoms began 5 days after completing a course of amoxicillin for streptococcal pharyngitis. Results of a gastrointestinal pathogen panel that included 18 bacterial, viral, and parasitic pathogens were negative. A stool sample result was positive for Clostridioides difficile<\/em> by polymerase chain reaction (PCR) testing and an enzyme immunoassay test for C difficile<\/em> toxin A and B had a negative result.<\/a><\/a><\/p>\n\n\n\n

How Do You Interpret These Test Results?<\/h4>\n\n\n\n
    \n
  1. Antibiotic treatment for C difficile<\/em> infection is not indicated.<\/li>\n\n\n\n
  2. Antibiotic treatment for C difficile<\/em> infection is warranted.<\/li>\n\n\n\n
  3. Stool testing for fecal leukocytes is necessary.<\/li>\n\n\n\n
  4. The gastrointestinal pathogen panel is likely a false-negative result.<\/li>\n<\/ol>\n\n\n\n

    <\/p>\n","protected":false},"excerpt":{"rendered":"

    JAMA Diagnostic Test Interpretation  August 2 […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[13,18],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/24584"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24584"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/24584\/revisions"}],"predecessor-version":[{"id":24587,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/24584\/revisions\/24587"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}