{"id":23025,"date":"2023-02-12T04:02:00","date_gmt":"2023-02-11T20:02:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=23025"},"modified":"2023-02-12T09:31:28","modified_gmt":"2023-02-12T01:31:28","slug":"icu-management-practice-%e9%99%a2%e5%89%8d%e9%9b%86%e6%9d%9f%e5%8c%96%e6%b2%bb%e7%96%97%e6%8e%aa%e6%96%bd%e4%bc%b4%e9%9a%8f%e6%84%9f%e6%9f%93%e6%80%a7%e4%bc%91%e5%85%8b%e7%97%85%e6%ad%bb%e7%8e%87","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=23025","title":{"rendered":"[ICU Management &#038; Practice]: \u9662\u524d\u96c6\u675f\u5316\u6cbb\u7597\u63aa\u65bd\u4f34\u968f\u611f\u67d3\u6027\u4f11\u514b\u75c5\u6b7b\u7387\u964d\u4f4e"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\">Prehospital Bundle of Care Associated With Mortality Decrease in Septic Shock<\/h1>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/res.cloudinary.com\/healthmanagement-org\/image\/upload\/f_auto,fl_lossy\/v1665460805\/cw\/00122458_cw_image.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<p>Over 50 million people worldwide suffer from sepsis every year. Sepsis causes nearly 11 million deaths and is responsible for one-third to half of all in-hospital deaths. The mortality rate for sepsis ranges from 10 to 20%. For septic shock, the most serious form of sepsis, the mortality rate can range from 50 to 60%.&nbsp;<\/p>\n\n\n\n<p>Guidelines recommend early recognition, severity assessment and early treatment implementation to reduce septic shock mortality. The 2019 guidelines, in particular, highlight the need to implement an early strategy, \"hour 1 bundle,\" to be started within the first hour. A bundle of care, including antibiotic treatment and haemodynamic optimisation, is believed to be more efficient than a single treatment. Evidence suggests that this early intervention is strongly associated with improvement in patient outcomes.&nbsp;<\/p>\n\n\n\n<p>However, 70% of sepsis occurs outside the hospital environment. The approximate median time to reach a hospital is around 60 minutes and could take longer - up to 120 minutes. Hence, there is a need to further clarify the impact of prehospital interventions on sepsis and septic shock outcomes. There are no specific guidelines for septic shock prehospital care, and there is a wide variation among physician practices.<\/p>\n\n\n\n<p>A new study investigated the association between 30-day mortality in patients with septic shock and a prehospital bundle of care completion, antibiotic administration and haemdoynamic optimisation. The goal was to determine whether an early bundle of care completion decreased 30-day mortality in patients with septic shock.&nbsp;<\/p>\n\n\n\n<p>The analysis included 354 patients with septic shock who required prehospital mobile ICU (mICU) intervention. Pulmonary, digestive, and urinary infections were the cause of septic shock in 49%, 25%, and 13% of the patients, respectively. The overall 30-day mortality was 32%. 20% of the patients received prehospital antibiotic therapy and fluid expansion.<\/p>\n\n\n\n<p>Study findings show that a prehospital bundle of care that includes antibiotic therapy and haemodynamic optimisation, is associated with a decrease in 30-day mortality in patients suffering from septic shock cared for by an mICU.<\/p>\n\n\n\n<p>Source:&nbsp;<a href=\"https:\/\/journals.lww.com\/ccmjournal\/Fulltext\/2022\/10000\/Prehospital_Bundle_of_Care_Based_on_Antibiotic.3.aspx\" target=\"_blank\" rel=\"noreferrer noopener\">Critical Care Medicine<\/a><\/p>\n\n\n\n<p>Image Credit: iStock<\/p>\n\n\n\n<p><a href=\"https:\/\/healthmanagement.org\/c\/sepsis\/news\/world-sepsis-day\">\u00ab\u00ab&nbsp;World Sepsis Day<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/healthmanagement.org\/c\/sepsis\/news\/source-control-and-sepsis-management\">Source Control and Sepsis Management \u00bb\u00bb<\/a><\/p>\n\n\n\n<h4 class=\"wp-block-heading\">References:<\/h4>\n\n\n\n<p>Jouffroy R, Gilbert B, Tourtier JP et al. (2022)&nbsp;<a href=\"https:\/\/journals.lww.com\/ccmjournal\/Fulltext\/2022\/10000\/Prehospital_Bundle_of_Care_Based_on_Antibiotic.3.aspx\" target=\"_blank\" rel=\"noreferrer noopener\">Prehospital Bundle of Care Based on Antibiotic Therapy and Hemodynamic Optimization Is Associated With a 30-Day Mortality Decrease in Patients With Septic Shock<\/a>. Crit Care Med. 50(10):1440-1448.<\/p>\n\n\n\n<p>Published on : Tue, 11 Oct 2022<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prehospital Bundle of Care Associated With Mortality De [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[24,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/23025"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23025"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/23025\/revisions"}],"predecessor-version":[{"id":23026,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/23025\/revisions\/23026"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}