{"id":22674,"date":"2023-01-27T03:10:00","date_gmt":"2023-01-26T19:10:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=22674"},"modified":"2023-01-27T06:02:47","modified_gmt":"2023-01-26T22:02:47","slug":"icu-management-practice-%e8%a1%a5%e5%85%85%e7%bb%b4%e7%94%9f%e7%b4%a0d%e4%b8%8e%e6%96%b0%e5%86%a0%e8%82%ba%e7%82%8e%e7%9a%84%e9%a3%8e%e9%99%a9","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=22674","title":{"rendered":"[ICU Management & Practice]: \u8865\u5145\u7ef4\u751f\u7d20D\u4e0e\u65b0\u51a0\u80ba\u708e\u7684\u98ce\u9669"},"content":{"rendered":"\n

Vitamin D Supplements and Risk of COVID-19<\/h1>\n\n\n\n
\"\"\/<\/figure>\n\n\n\n

Findings from two large clinical trials show that increasing vitamin D levels in adults during the COVID-19 pandemic was not associated with protection against coronavirus or other respiratory tract infections. <\/p>\n\n\n\n

Vitamin D has long been recognised to support innate immune responses to respiratory viruses and bacteria. Some studies show that vitamin D may protect against respiratory tract infections, particularly among people who are vitamin D deficient. During the pandemic, vitamin D has received much attention as a potential strategy for preventing and treating COVID-19. But the evidence so far shows mixed results. <\/p>\n\n\n\n

The first trial was carried out in the U.K. with 6200 patients. None of the participants used vitamin D supplements at the time of enrollment. Half of the participants underwent a vitamin D blood test. Those with low vitamin D levels received either 3200 IU\/day or 800 IU\/day of vitamin D supplements for six months, while the other half received no test or supplements.<\/p>\n\n\n\n

The study showed no effect of vitamin D on diagnosed acute respiratory tract infections or lateral flow test or RT-PCR confirmed covid-19 cases over a six-month follow-up period. Adverse events were similar between the two groups.<\/p>\n\n\n\n

The second trial was conducted in Norway using cod liver oil which contains low doses of vitamin D and vitamin A as well as omega-3 fatty acids. Thirty-four thousand seven hundred forty-one people who were not using vitamin D supplements were enrolled in the study and received either 5 mL cod liver oil or 5 mL placebo daily for six months. 86% of the study participants had adequate vitamin D levels at the start of the study. Results of this study also showed no effect of cod liver oil on acute respiratory infections or COVID-19 compared with placebo. There were no differences in the side effects either. <\/p>\n\n\n\n

Findings from both these studies suggest that vitamin D supplements do not reduce the risk of COVID-19 or other acute respiratory infections. Vaccination continues to be the most effective way to protect people from COVID-19. <\/p>\n\n\n\n

Source: BMJ<\/a><\/p>\n\n\n\n

Image Credit: iStock<\/p>\n\n\n\n

\u00ab\u00ab ICU Professionals\u2019 Knowledge of End-of-Life Decision-Making Law <\/a><\/p>\n\n\n\n

Clinical Nutrition Issues in 2022 \u00bb\u00bb<\/a><\/p>\n\n\n\n

References:<\/h4>\n\n\n\n

Jolliffe DA, Talaei M, Vivalid G et al. (2022) Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respiratory tract infection and covid-19: phase 3 randomised controlled trial (CORONAVIT).<\/a> BMJ. 378:e071230.<\/p>\n\n\n\n

Published on : Tue, 13 Sep 2022<\/p>\n","protected":false},"excerpt":{"rendered":"

Vitamin D Supplements and Risk of COVID-19 Findings fro […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[24,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/22674"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=22674"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/22674\/revisions"}],"predecessor-version":[{"id":22675,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/22674\/revisions\/22675"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=22674"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=22674"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=22674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}