{"id":22421,"date":"2022-09-17T05:04:00","date_gmt":"2022-09-16T21:04:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=22421"},"modified":"2022-09-17T06:51:39","modified_gmt":"2022-09-16T22:51:39","slug":"jama%e8%af%8a%e6%96%ad%e7%bb%93%e6%9e%9c%e8%a7%a3%e8%af%bb%ef%bc%9a%e8%a1%80%e6%b8%85%e8%83%b1%e6%8a%91%e7%b4%a0c%e4%bc%b0%e6%b5%8bgfr","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=22421","title":{"rendered":"[JAMA\u8bca\u65ad\u7ed3\u679c\u89e3\u8bfb]\uff1a\u8840\u6e05\u80f1\u6291\u7d20C\u4f30\u6d4bGFR\uff08\u95ee\u9898\uff09"},"content":{"rendered":"\n

JAMA Diagnostic Test Interpretation <\/p>\n\n\n\n

August 8, 2022<\/p>\n\n\n\n

Serum Cystatin C for Estimation of GFR<\/h1>\n\n\n\n

Michael G.\u00a0Shlipak,\u00a0Lesley A.\u00a0Inker,\u00a0Josef\u00a0Coresh<\/h3>\n\n\n\n

JAMA.\u00a0<\/em>Published online August 8, 2022. doi:10.1001\/jama.2022.12407<\/h3>\n\n\n\n

Case<\/a><\/h2>\n\n\n\n

An 80-year-old man with type 2 diabetes and hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his angiotensin-converting enzyme inhibitor. The patient was frail, sedentary, and had a body mass index of 37. Select blood testing results are shown in\u00a0Table 1<\/a>. His estimated glomerular filtration rate (eGFR) was calculated using 3 equations that incorporated creatinine (eGFRcr), cystatin C (eGFRcys), and both creatinine and cystatin C (eGFRcr-cys), as shown in\u00a0Table 2<\/a>.<\/p>\n\n\n\n

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\"\"\/<\/figure>\n\n\n\n

How Do You Interpret These Test Results?<\/h4>\n\n\n\n
  1. The estimated glomerular filtration rate calculated using creatinine (eGFRcr) may be inaccurate because the patient is frail and sedentary.<\/li>
  2. The eGFRcr of 64 mL\/min\/1.73 m2<\/sup>\u00a0indicates normal kidney function.<\/li>
  3. The eGFR calculated using cystatin C (eGFRcys) may be low because the patient has decreased muscle mass.<\/li>
  4. The eGFRcys may be reduced because the patient has type 2 diabetes.<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"

    JAMA Diagnostic Test Interpretation  August 8 […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[13,18],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/22421"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=22421"}],"version-history":[{"count":3,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/22421\/revisions"}],"predecessor-version":[{"id":22638,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/22421\/revisions\/22638"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=22421"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=22421"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=22421"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}