{"id":21179,"date":"2022-03-31T04:41:00","date_gmt":"2022-03-30T20:41:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=21179"},"modified":"2022-03-31T06:58:24","modified_gmt":"2022-03-30T22:58:24","slug":"jama%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9aicu%e6%b2%bb%e7%96%97%e5%90%8e%e5%ad%98%e6%b4%bb%e4%b8%80%e5%b9%b4%e7%9a%84%e6%96%b0%e5%86%a0%e8%82%ba%e7%82%8e%e6%82%a3%e8%80%85%e7%9a%84%e4%b8%b4","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=21179","title":{"rendered":"[JAMA\u53d1\u8868\u8bba\u6587]\uff1aICU\u6cbb\u7597\u540e\u5b58\u6d3b\u4e00\u5e74\u7684\u65b0\u51a0\u80ba\u708e\u60a3\u8005\u7684\u4e34\u5e8a\u9884\u540e"},"content":{"rendered":"\n

Original Investigation Caring for the Critically Ill PatientJanuary 24, 2022<\/p>\n\n\n\n

Clinical Outcomes Among Patients With 1-Year Survival Following Intensive Care Unit Treatment for COVID-19<\/h1>\n\n\n\n

Hidde\u00a0Heesakkers,\u00a0Johannes G.\u00a0van der Hoeven,\u00a0Stijn\u00a0Corsten, et al<\/h3>\n\n\n\n

JAMA.\u00a0<\/em>Published online January 24, 2022. doi:10.1001\/jama.2022.0040<\/h3>\n\n\n\n

Key Points<\/p>\n\n\n\n

Question<\/strong>  What are the 1-year outcomes among patients who survive intensive care unit (ICU) treatment for COVID-19?<\/p>\n\n\n\n

Findings<\/strong>  In this exploratory multicenter prospective cohort study that included 246 patients who were alive 1 year following ICU treatment for COVID-19, 74.3% reported physical symptoms, 26.2% reported mental symptoms, and 16.2% reported cognitive symptoms.<\/p>\n\n\n\n

Meaning<\/strong>  Physical, mental, and cognitive symptoms were frequent 1 year after ICU treatment for COVID-19.<\/a>Abstract<\/p>\n\n\n\n

Importance<\/strong>  One-year outcomes in patients who have had COVID-19 and who received treatment in the intensive care unit (ICU) are unknown.<\/p>\n\n\n\n

Objective<\/strong>  To assess the occurrence of physical, mental, and cognitive symptoms among patients with COVID-19 at 1 year after ICU treatment.<\/p>\n\n\n\n

Design, Setting, and Participants<\/strong>  An exploratory prospective multicenter cohort study conducted in ICUs of 11 Dutch hospitals. Patients (N\u2009=\u2009452) with COVID-19, aged 16 years and older, and alive after hospital discharge following admission to 1 of the 11 ICUs during the first COVID-19 surge (March 1, 2020, until July 1, 2020) were eligible for inclusion. Patients were followed up for 1 year, and the date of final follow-up was June 16, 2021.<\/p>\n\n\n\n

Exposures<\/strong>  Patients with COVID-19 who received ICU treatment and survived 1 year after ICU admission.<\/p>\n\n\n\n

Main Outcomes and Measures<\/strong>  The main outcomes were self-reported occurrence of physical symptoms (frailty [Clinical Frailty Scale score \u22655], fatigue [Checklist Individual Strength\u2014fatigue subscale score \u226527], physical problems), mental symptoms (anxiety [Hospital Anxiety and Depression {HADS} subscale score \u22658], depression [HADS subscale score \u22658], posttraumatic stress disorder [mean Impact of Event Scale score \u22651.75]), and cognitive symptoms (Cognitive Failure Questionnaire\u201414 score \u226543) 1 year after ICU treatment and measured with validated questionnaires.<\/p>\n\n\n\n

Results<\/strong>  Of the 452 eligible patients, 301 (66.8%) patients could be included, and 246 (81.5%) patients (mean [SD] age, 61.2 [9.3] years; 176 men [71.5%]; median ICU stay, 18 days [IQR, 11 to 32]) completed the 1-year follow-up questionnaires. At 1 year after ICU treatment for COVID-19, physical symptoms were reported by 182 of 245 patients (74.3% [95% CI, 68.3% to 79.6%]), mental symptoms were reported by 64 of 244 patients (26.2% [95% CI, 20.8% to 32.2%]), and cognitive symptoms were reported by 39 of 241 patients (16.2% [95% CI, 11.8% to 21.5%]). The most frequently reported new physical problems were weakened condition (95\/244 patients [38.9%]), joint stiffness (64\/243 patients [26.3%]) joint pain (62\/243 patients [25.5%]), muscle weakness (60\/242 patients [24.8%]) and myalgia (52\/244 patients [21.3%]).<\/p>\n\n\n\n

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Conclusions and Relevance<\/strong>  In this exploratory study of patients in 11 Dutch hospitals who survived 1 year following ICU treatment for COVID-19, physical, mental, or cognitive symptoms were frequently reported.<\/p>\n","protected":false},"excerpt":{"rendered":"

Original Investigation Caring for the Critically I […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/21179"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21179"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/21179\/revisions"}],"predecessor-version":[{"id":21531,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/21179\/revisions\/21531"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21179"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=21179"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=21179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}