{"id":20694,"date":"2021-11-01T05:01:00","date_gmt":"2021-10-31T21:01:00","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=20694"},"modified":"2021-11-01T05:47:57","modified_gmt":"2021-10-31T21:47:57","slug":"jama%e5%8f%91%e8%a1%a8%e6%96%87%e7%ab%a0%ef%bc%9a%e6%9c%89%e5%85%b3%e9%80%9a%e8%bf%87%e6%8a%97%e4%bd%93%e6%a3%80%e6%b5%8b%e8%af%84%e4%bb%b7%e6%96%b0%e5%86%a0%e7%97%85%e6%af%92%e5%85%8d%e7%96%ab-2","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=20694","title":{"rendered":"[JAMA\u53d1\u8868\u6587\u7ae0]\uff1a\u6709\u5173\u901a\u8fc7\u6297\u4f53\u68c0\u6d4b\u8bc4\u4ef7\u65b0\u51a0\u75c5\u6bd2\u514d\u75ab\u529b\u7684\u9519\u8bef\u8ba4\u8bc6\uff08\u8bd1\u6587\uff09"},"content":{"rendered":"\n

Medical News & Perspectives October 21, 2021<\/p>\n\n\n\n

The Flawed Science of Antibody Testing for SARS-CoV-2 Immunity<\/h1>\n\n\n\n

Jennifer Abbasi<\/h3>\n\n\n\n

JAMA. <\/em>Published online October 21, 2021. doi:10.1001\/jama.2021.18919<\/h3>\n\n\n\n

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Theel\u5728\u4e00\u6b21\u91c7\u8bbf\u4e2d\u8bf4\uff1a\u201c\u5373\u4fbf\u4eba\u4eec\u4f53\u5185\u6709\u4e2d\u548c\u6297\u4f53\uff0c\u4ecd\u7136\u53ef\u80fd\u4f1a\u88ab\u611f\u67d3\u3002\u6211\u4eec\u77e5\u9053\u6297\u4f53\u6c34\u5e73\uff0c\u5c24\u5176\u662f\u662f\u4e2d\u548c\u6297\u4f53\u6c34\u5e73\u8d8a\u9ad8\u8d8a\u597d\uff0c\u4f46\u6211\u4eec\u5e76\u4e0d\u77e5\u9053\u591a\u9ad8\u6c34\u5e73\u624d\u7b97\u8db3\u591f\u3002\u201d<\/p>\n\n\n\n

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\u6839\u636eTheel\u7684\u8bf4\u6cd5\uff0c\u5982\u679c\u8981\u786e\u5b9a\u4e0e\u4fdd\u62a4\u4f5c\u7528\u7684\u76f8\u5173\u6027\u548c\u9608\u503c\uff0c\u68c0\u6d4b\u9700\u8981\u6807\u51c6\u5316\u548c\u6821\u6b63\uff0c\u5c31\u50cf\u5176\u4ed6\u53ef\u7528\u75ab\u82d7\u9884\u9632\u7684\u75be\u75c5\uff08\u5305\u62ec\u7834\u4f24\u98ce\u3001\u767d\u5589\u548c\u9ebb\u75b9\uff09\u7684\u6297\u4f53\u68c0\u6d4b\u4e00\u6837\u3002\u5979\u8bf4\uff0c\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u53ea\u6709\u4e00\u79cd\u6765\u81ea\u7f8e\u56fdOrtho-Clinical Diagnostics\u516c\u53f8\u7684\u5e02\u552e\u65b0\u51a0\u75c5\u6bd2\u6297\u4f53\u68c0\u6d4b\u5df2\u8fbe\u5230\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u7684\u53c2\u8003\u6807\u51c6\u3002<\/p>\n\n\n\n

\u66f4\u91cd\u8981\u7684\u662f\uff0c\u6240\u6709\u6297\u4f53\u90fd\u80fd\u4e0e\u75c5\u6bd2\u7ed3\u5408\uff0c\u4f46\u53ea\u6709\u90e8\u5206\u6297\u4f53\u80fd\u4e2d\u548c\u75c5\u6bd2\uff0c\u5df2\u7ecf\u5f97\u5230\u6388\u6743\u7684\u7684\u4e34\u5e8a\u68c0\u6d4b\u65e0\u4e00\u80fd\u591f\u533a\u5206\u8fd9\u4e9b\u6297\u4f53\u3002\u5c3d\u7ba1\u90e8\u5206\u7814\u7a76\u8868\u660e\uff0c\u7ed3\u5408\u6297\u4f53\u548c\u4e2d\u548c\u6297\u4f53\u6c34\u5e73\u4e4b\u95f4\u5b58\u5728\u76f8\u5173\u6027\uff0c\u4f46\u5b83\u4eec\u5e76\u4e0d\u5b8c\u5168\u5339\u914d\u3002<\/p>\n\n\n\n

Doria Rose\u6307\u51fa\uff0c\u6d4b\u5b9a\u4e2d\u548c\u6297\u4f53\u662f\u975e\u5e38\u590d\u6742\u7684\u68c0\u6d4b\uff0c\u4ec5\u5728\u5c11\u6570\u5b9e\u9a8c\u5ba4\u53ef\u4ee5\u8fdb\u884c\uff0c\u4e14\u5c1a\u672a\u6269\u5927\u7528\u4e8e\u8bca\u65ad\u76ee\u7684\u3002Epitome Risk Solutions\u5b50\u516c\u53f8FourthWall Testing\u6240\u9500\u552e\u7684\u68c0\u6d4b\u8bd5\u5242\u76d2\uff0c\u5b9e\u9645\u4e0a\u662fFDA\u6388\u6743\u7684GenScript cPass\u65b0\u51a0\u75c5\u6bd2\u4e2d\u548c\u6297\u4f53\u68c0\u6d4b\u8bd5\u5242\u76d2\u7684\u5bb6\u7528\u7248\u672c\uff0c\u8be5\u8bd5\u5242\u76d2\u80fd\u591f\u95f4\u63a5\u6d4b\u5b9a\u4e2d\u548c\u6297\u4f53\u3002\u636e\u7f8e\u56fdFDA\u53d1\u8a00\u4eba\u8bf4\uff0ccPass\u68c0\u6d4b\u5e76\u6ca1\u6709\u83b7\u5f97\u5728\u5bb6\u4e2d\u91c7\u96c6\u6837\u672c\u7684\u6279\u51c6\u3002\u5c3d\u7ba1Epitome\u5728\u5e02\u573a\u4e0a\u5927\u8086\u5ba3\u4f20\uff0cGenScript\u8868\u793a\uff0c\u5ba2\u6237\u201c\u4e0d\u5e94\u5c06\u8be5\u68c0\u6d4b\u7ed3\u679c\u89e3\u8bfb\u4e3a\u9488\u5bf9\u518d\u6b21\u611f\u67d3\u7684\u514d\u75ab\u529b\u6216\u4fdd\u62a4\u4f5c\u7528\u3002\u201d<\/p>\n\n\n\n

\u7ba1\u7406\u9884\u671f<\/strong><\/h3>\n\n\n\n

\u5bf9\u4e8e\u8d39\u57ce\u513f\u7ae5\u533b\u9662\u75ab\u82d7\u6559\u80b2\u4e2d\u5fc3\u4e3b\u4efbPaul Offit\u533b\u5b66\u535a\u58eb\u6765\u8bf4\uff0c\u5f3a\u70c8\u53cd\u5bf9\u4f7f\u7528\u8840\u6db2\u68c0\u6d4b\u8bc4\u4f30\u4e2a\u4f53\u662f\u5426\u53d7\u5230\u4fdd\u62a4\u7684\u53e6\u4e00\u8bba\u70b9\u662f\uff1a\u5faa\u73af\u4e2d\u7684\u6297\u4f53\u6c34\u5e73\u4e0d\u80fd\u53cd\u6620\u65b0\u51a0\u75c5\u6bd2\u514d\u75ab\u529b\u7684\u6574\u4f53\u60c5\u51b5\u3002<\/p>\n\n\n\n

Offit\u5728\u91c7\u8bbf\u4e2d\u8bf4\uff0c\u201c\u4e0e\u91cd\u75c7\u4fdd\u62a4\u4f5c\u7528\u76f8\u5173\u7684\u514d\u75ab\u6210\u5206\u662f\u8bb0\u5fc6B\u7ec6\u80de\uff0c\u8fd9\u4e9b\u7ec6\u80de\u4e0d\u4f1a\u4ea7\u751f\u6297\u4f53\uff0c\u4f46\u5b83\u4eec\u8bb0\u5f97\u4ee5\u524d\u89c1\u8fc7\u8fd9\u79cd\u65b0\u51a0\u75c5\u6bd2\u68d8\u7a81\u86cb\u767d\u3002\u201d<\/p>\n\n\n\n

Theel\u6307\u51fa\uff0c\u5728\u5929\u7136\u611f\u67d3\u6216\u63a5\u79cd\u75ab\u82d72-3\u4e2a\u6708\u540e\uff0c\u5faa\u73af\u4e2d\u7684\u75c5\u6bd2\u6297\u4f53\u8fbe\u5230\u5cf0\u503c\uff0c\u7136\u540e\u5f00\u59cb\u4e0b\u964d\u3002\u4f46\u514d\u75ab\u7cfb\u7edf\u7684\u9632\u5fa1\u80fd\u529b\u53ef\u4ee5\u6301\u7eed\u66f4\u957f\u65f6\u95f4\u3002\u5979\u8bf4\uff1a\u201c\u4ec5\u4ec5\u770b\u5230\u6297\u4f53\u6c34\u5e73\u4e0b\u964d\u5e76\u4e0d\u4e00\u5b9a\u610f\u5473\u7740\u4f60\u7684\u514d\u75ab\u529b\u5df2\u7ecf\u6d88\u5931\u3002\u6211\u4eec\u4ece\u5927\u91cf\u7814\u7a76\u4e2d\u4e86\u89e3\u5230\uff0c\u8bb0\u5fc6T\u7ec6\u80de\u548c\u8bb0\u5fc6B\u7ec6\u80de\u81f3\u5c11\u4f1a\u6301\u7eed6-8\u4e2a\u6708\uff0c\u5e76\u7ee7\u7eed\u8fdb\u5316\u3001\u6210\u719f\uff0c\u800c\u8fd9\u4e9b\u4fe1\u606f\u90fd\u4e0d\u4f1a\u901a\u8fc7\u6297\u4f53\u68c0\u6d4b\u5f97\u5230\u3002\u201d<\/p>\n\n\n\n

Offit\u89e3\u91ca\u8bf4\uff0c\u518d\u6b21\u611f\u67d3\u75c5\u6bd2\u4f1a\u6fc0\u6d3b\u8bb0\u5fc6B\u7ec6\u80de\uff0c\u4f7f\u5176\u5206\u5316\u4e3a\u6297\u4f53\u5206\u6ccc\u7ec6\u80de\u3002\u8fd9\u4e00\u8fc7\u7a0b\u53ef\u80fd\u9700\u89813-5\u5929\uff0c\u56e0\u6b64\uff0c\u5c3d\u7ba1\u4e0d\u80fd\u963b\u6b62\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\u7684\u53d1\u751f\uff0c\u4f46\u786e\u5b9e\u6709\u52a9\u4e8e\u9884\u9632\u91cd\u75c7\u611f\u67d3\u3002\u5728\u4ed6\u770b\u6765\uff0c\u8fd9\u662f\u6210\u529f\u7684\uff1a\u201c\u75ab\u82d7\u7684\u76ee\u6807\u5728\u4e8e\u4fdd\u62a4\u4f60\u514d\u4e8e\u91cd\u75c7\u201d\u3002<\/p>\n\n\n\n

\u8fc4\u4eca\u4e3a\u6b62\uff0c\u6211\u4eec\u5df2\u7ecf\u505a\u5230\u4e86\u8fd9\u4e00\u70b9\u3002\u5c3d\u7ba1\u6709\u6570\u636e\u8868\u660e\uff0c\u5728\u7f8e\u56fd\u7531mRNA\u75ab\u82d7\u8bf1\u5bfc\u7684\u5bf9\u611f\u67d3\u548c\u6709\u75c7\u72b6\u75be\u75c5\u7684\u4fdd\u62a4\u4f5c\u7528\u6b63\u5728\u4e0b\u964d\uff0c\u4f46\u63a5\u79cd\u75ab\u82d7\u4ecd\u7136\u80fd\u9884\u9632\u91cd\u75c7\u3001\u4f4f\u9662\u548c\u6b7b\u4ea1\u3002<\/p>\n\n\n\n

\u8fd9\u4e9b\u6570\u636e\u4f3c\u4e4e\u4e0e\u5e7f\u6cdb\u62a5\u9053\u7684\u4ee5\u8272\u5217\u63a5\u79cd\u75ab\u82d7\u8005\u4f4f\u9662\u7387\u4e0a\u5347\u76f8\u77db\u76fe\u3002\u4f46\u6839\u636eOffit\u6240\u8bf4\uff0c\u4ee5\u8272\u5217\u7684\u65b0\u51a0\u80ba\u708e\u4f4f\u9662\u8d8b\u52bf\u4e0d\u80fd\u76f4\u63a5\u5e94\u7528\u4e8e\u7f8e\u56fd\u3002\u4ed6\u8bf4\uff1a\u201c\u4ed6\u4eec\u5bf9\u4e8e\u75be\u75c5\u4e25\u91cd\u7a0b\u5ea6\u6709\u4e0d\u540c\u7684\u5b9a\u4e49\uff0c\u4ed6\u4eec\u6ca1\u6709\u6211\u4eec\u4e25\u683c\u3002\u201d<\/p>\n\n\n\n

Offit\u66fe\u5728FDA\u75ab\u82d7\u54a8\u8be2\u59d4\u5458\u4f1a\u4efb\u804c\uff0c\u8be5\u59d4\u5458\u4f1a\u5efa\u8bae\u5927\u591a\u6570\u63a5\u79cdBNT162b2\u75ab\u82d7\u7684\u6210\u5e74\u4eba\u4e0d\u8981\u6ce8\u5c04\u75ab\u82d7\u52a0\u5f3a\u9488\u3002\u76ee\u524d\uff0c\u75ab\u82d7\u52a0\u5f3a\u9488\u4ec5\u5f97\u5230\u6388\u6743\u7528\u4e8e\u91cd\u75c7\u98ce\u9669\u6700\u9ad8\u7684\u4eba\u7fa4\uff1a65\u5c81\u6216\u4ee5\u4e0a\u7684\u6210\u5e74\u4eba\uff0c\u4ee5\u53ca\u60a3\u6709\u67d0\u4e9b\u57fa\u7840\u75be\u75c5\uff0c\u5728\u9ad8\u5371\u73af\u5883\u4e2d\u751f\u6d3b\u6216\u5de5\u4f5c\uff0c\u6216\u5728\u957f\u671f\u62a4\u7406\u673a\u6784\u4e2d\u751f\u6d3b\u7684\u6210\u5e74\u4eba\u3002\uff08\u6839\u636eCDC\u7684\u8bf4\u6cd5\uff0c\u4e2d\u91cd\u5ea6\u514d\u75ab\u529f\u80fd\u4f4e\u4e0b\u5e76\u63a5\u79cdBNT162b2\u6216mRNA-1273\u75ab\u82d7\u7684\u4eba\u5e94\u8be5\u63a5\u79cd\u75ab\u82d7\u52a0\u5f3a\u9488\u3002\uff09<\/p>\n\n\n\n

Offit\u8bf4\uff0c\u968f\u7740\u6297\u4f53\u7684\u51cf\u5c11\uff0c\u5bf9\u65e0\u75c7\u72b6\u6216\u8f7b\u75c7\u611f\u67d3\u7684\u6613\u611f\u6027\u589e\u52a0\u3002\u5728\u7f8e\u56fd\u6700\u8fd1\u7684\u4e00\u9879\u7814\u7a76\u4e2d\uff0cBNT162b2\u75ab\u82d7\u5728\u63a5\u79cd6\u4e2a\u6708\u540e\u5bf9Delta\uff08B.1.617.2\uff09\u53d8\u5f02\u682a\u611f\u67d3\u4f4f\u9662\u7684\u4fdd\u62a4\u7387\u4e3a93%\uff0c\u4f46\u5bf9Delta\u53d8\u5f02\u682a\u611f\u67d3\u7684\u603b\u4f53\u4fdd\u62a4\u7387\u4ece\u5b8c\u6210\u63a5\u79cd\u540e\u7b2c\u4e00\u4e2a\u6708\u768493%\u4e0b\u964d\u52304\u4e2a\u6708\u540e\u768453%\u3002\u4f5c\u8005\u5c06\u8fd9\u79cd\u4e0b\u964d\u4e3b\u8981\u5f52\u56e0\u4e8e\u514d\u75ab\u529b\u7684\u4e0b\u964d\uff0c\u800c\u4e0d\u662f\u53d8\u5f02\u682a\u5bf9\u75ab\u82d7\u4fdd\u62a4\u4f5c\u7528\u7684\u9003\u9038\u3002<\/p>\n\n\n\n

Offit\u627f\u8ba4\u4efb\u4f55\u611f\u67d3\u90fd\u53ef\u80fd\u662f\u7834\u574f\u6027\u7684\uff0c\u4f46\u901a\u8fc7\u5468\u671f\u6027\u6ce8\u5c04\u52a0\u5f3a\u9488\u4ee5\u4fdd\u6301\u4e2d\u548c\u6297\u4f53\u7684\u9ad8\u6c34\u5e73\u5e76\u4e0d\u73b0\u5b9e\u3002\u4ed6\u8bf4\uff0c\u8fd9\u7c7b\u4f3c\u4e8e\u201c\u628a\u77f3\u5934\u6eda\u4e0a\u5c71\uff0c\u7ed3\u679c\u77f3\u5934\u53c8\u4f1a\u6eda\u4e0b\u5c71\u6765\u3002\u201d<\/p>\n\n\n\n

\u4e0eTheel\u76f8\u4f3c\uff0c\u4ed6\u627f\u8ba4\u4ecd\u7136\u4f1a\u53d1\u751f\u7a81\u7834\u6027\u611f\u67d3\u3002\u4ed6\u8bf4\uff1a\u201c\u4f60\u53ef\u4ee5\u5728\u8840\u6db2\u5faa\u73af\u4e2d\u6709\u975e\u5e38\u9ad8\u6c34\u5e73\u7684\u4e2d\u548c\u6297\u4f53\uff0c\u8fd9\u5e76\u4e0d\u80fd\u963b\u6b62\u75c5\u6bd2\u9644\u7740\u5728\u4f60\u7684\u9f3b\u5b50\u4e0a\u5e76\u5f00\u59cb\u81ea\u6211\u7e41\u6b96\u3002\u8fd9\u662f\u4e00\u79cd\u65e0\u75c7\u72b6\u611f\u67d3\u201d\u3002<\/p>\n\n\n\n

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Medical News & Perspectives October 21,&n […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[24,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/20694"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20694"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/20694\/revisions"}],"predecessor-version":[{"id":20695,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/20694\/revisions\/20695"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20694"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=20694"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=20694"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}