{"id":17740,"date":"2019-09-28T05:39:45","date_gmt":"2019-09-27T21:39:45","guid":{"rendered":"http:\/\/csccm.org.cn\/?p=17740"},"modified":"2019-10-29T22:53:17","modified_gmt":"2019-10-29T14:53:17","slug":"jama%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e7%be%8e%e5%9b%bd","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=17740","title":{"rendered":"[JAMA\u53d1\u8868\u8bba\u6587]\uff1a\u7f8e\u56fd\u4ea7\u5987\u8113\u6bd2\u75c7\u53d1\u75c5\u7387\u53ca\u8113\u6bd2\u75c7\u76f8\u5173\u4ea7\u5987\u6b7b\u4ea1\u7387"},"content":{"rendered":"\n<p>Research Letter&nbsp;September&nbsp;3,&nbsp;2019<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Incidence of Maternal Sepsis and Sepsis-Related Maternal Deaths in the United States<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Matthew K.&nbsp;Hensley,&nbsp;Melissa E.&nbsp;Bauer,&nbsp;Lindsay K.&nbsp;Admon,&nbsp;et al.<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\"><em>JAMA.&nbsp;<\/em>2019;322(9):890-892. doi:10.1001\/jama.2019.9818<\/h3>\n\n\n\n<p>Results<\/p>\n\n\n\n<p>From 63\u202f665\u202f593 hospitalizations in the NRD (2013-2016), there were 5\u202f957\u202f678 delivery hospitalizations with discharges in January through October, of which 32.5% were cesarean deliveries. There were 2905 deliveries complicated by sepsis (0.038%; 95% CI, 0.037%-0.040%); 49.8% (95% CI, 47.7%-52.0%) were complicated during delivery hospitalization and 50.3% (95% CI, 48.1%-52.4%) after delivery discharge. Sepsis readmissions occurred a mean of 13.6 (SD, 11.2) days after discharge from delivery hospitalization.<\/p>\n\n\n\n<p>Maternal sepsis episodes after delivery discharge, compared with during delivery hospitalization, occurred in women with fewer comorbidities (mean, 1.9 vs 2.6; difference, \u22120.7 [95% CI, \u22120.8 to \u22120.5];&nbsp;<em>P<\/em>\u2009&lt;\u2009.001), were less frequently associated with cesarean deliveries (49.6% vs 63.7%; difference, \u221215.7% [95% CI, \u221219.2% to \u221212.1%];&nbsp;<em>P<\/em>\u2009&lt;\u2009.001), had a higher percentage of acute kidney dysfunction (35.2% vs 23.9%; difference, 10.6% [95% CI, 7.3%-13.9%];&nbsp;<em>P<\/em>\u2009&lt;\u2009.001), and had a lower percentage of genitourinary infection (39.8% vs 49.2%; difference, \u22127.5% [95% CI, \u221211.1% to \u22123.9%];&nbsp;<em>P<\/em>\u2009&lt;\u2009.001) (<a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2749204#jld190036t1\">Table 1<\/a>).<\/p>\n\n\n\n<p>There were 408 delivery hospitalizations (0.007%; 95% CI, 0.006%-0.007%) that were followed by maternal death; 74.4% (95% CI, 69.6%-78.6%) during delivery hospitalization and 25.6% (95% CI, 21.4%-30.4%) after delivery discharge (<a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2749204#jld190036t2\">Table 2<\/a>). Overall, 95 (22.6%; 95% CI, 18.7%-27.1%) of the maternal deaths were sepsis-related; 17.3% (95% CI, 13.2%-22.4%) occurred during delivery hospitalization and 38.1% (95% CI, 29.0%-48.1%) occurred after delivery discharge.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/cdn.jamanetwork.com\/ama\/content_public\/journal\/jama\/938177\/m_jld190036t1.png?Expires=2147483647&amp;Signature=ncOVdDjj6WJfypymZlqOk3LJHSUj-zM9UqGXwKmOtee~EbE5bRVy7psbu3qLIWhHPnNrhzfp4nvzSVxAMSTZyrkWStOZzpTkJfwSbvlG~~~PtQmmcBBgPMgsFMf9c5Wq4Z09jCHE-nWvhChkQDk2pWcTcqvcv5paaSfiy0p2ZShhWqdZLiunQdoW5OptIsm8b-EZ0OQx7m9Kl-Bx5rwERrHsRZXnjl8xAVDLYs9F-rIGZCvDvJb6YJ~kIW2IK62r4gAC66PpVeSwZoVNuwcH00x7kcjhlCTizGQzkGG-00q4haOsZFhiKf43Hq-KGNtw7WPsvUb1GOAeE0o-xrRRHw__&amp;Key-Pair-Id=APKAIE5G5CRDK6RD3PGA\" alt=\"\"\/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Research Letter&nbsp;September&nbsp;3,&nbsp;2019 Incide [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/17740"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17740"}],"version-history":[{"count":3,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/17740\/revisions"}],"predecessor-version":[{"id":17760,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/17740\/revisions\/17760"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17740"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17740"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}