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Epidemiology of Weaning Outcome according to a New Definition. The WIND Study
Gaëtan Béduneau, Tài Pham, Frédérique Schortgen, et al.
Am J Respir Crit Care Med 2017; 195: 772-783
Rationale: 背景
The weaning process concerns all patients receiving mechanical ventilation. A previous classification into simple, prolonged, and difficult weaning ignored weaning failure and presupposed the use of spontaneous breathing trials.
脱机过程涉及所有接受机械通气的患者。既往分类方法将患...
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Recovery after Acute Kidney Injury
John A. Kellum, Florentina E. Sileanu, Azra Bihorac, et al
Am J Respir Crit Care Med 2017; 195: 784-791
Rationale: 背景
Little is known about how acute kidney injury (AKI) resolves, and whether patterns of reversal of renal dysfunction differ among patients with respect to ultimate recovery.
有关急性肾损伤(AKI)的恢复过程,以及不同患者肾脏功能障碍的逆转模式知之甚少。
Objectives: 目的
We sought to examine different patterns for AKI revers...
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High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial
Elizabeth Kepreotes, Bruce Whitehead, John Attia, et al
Lancet 2017; 389: 930-939
Summary
Background 背景
Bronchiolitis is the most common lung infection in infants and treatment focuses on management of respiratory distress and hypoxia. High-flow warm humidified oxygen (HFWHO) is increasingly used, but has...
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Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial
Estelle C Nijssen, Roger J Rennenberg, Patty J Nelemans, et al
Lancet 2017 (Published 20 February 2017)
DOI: http://dx.doi.org/10.1016/S0140-6736(17)30057-0
Background 背景
Intravenous saline is recommended in clinical pract...
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Research
Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data
Adrian R Martineau, David A Jolliffe, Richard L Hooper, et al.
doi: https://doi.org/10.1136/bmj.i6583 (Published 15 February 2017)
Cite this as: BMJ 2017;356:i6583
Abstract
Objectives
To assess the overall effect of vitamin D supplementation on risk of acute respiratory tract infection, and to identify factors modifying this e...
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Research Letter
February 21, 2017
Website Characteristics and Physician Reviews on Commercial Physician-Rating Websites
Tara Lagu, Katherine Metayer, Michael Moran; et al.
JAMA. 2017;317(7):766-768.
doi:10.1001/jama.2016.18553
Patients are increasingly seeking information about physicians online. Nearly 60% report that online reviews are important when choosing a physician. Because publicly reported quality data are not reported at the physician level, patients must consul...
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Intravenous zanamivir or oral oseltamivir for hospitalised patients with influenza: an international, randomised, double-blind, double-dummy, phase 3 trial
Francisco M Marty, Joan Vidal-Puigserver, Carol Clark, et al
Lancet Respir Med
Published: 13 January 2017
DOI: http://dx.doi.org/10.1016/S2213-2600(16)30435-0
Background 背景
Neuraminidase inhibitors are effective for the treatment of acute uncomplicated influenza. However, there is an unmet need for intravenous treat...
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Original Investigation
February 21, 2017
Effect of Fibrinogen Concentrate on Intraoperative Blood Loss Among Patients With Intraoperative Bleeding During High-Risk Cardiac SurgeryA Randomized Clinical Trial
Süleyman Bilecen, Joris A. H. de Groot, Cor J. Kalkman, et al
JAMA. 2017;317(7):738-747.
doi:10.1001/jama.2016.21037
Abstract 摘要
Importance 背景
Fibrinogen concentrate might partly restore coagulation defects and reduce intraoperative bleeding.
纤维蛋白原可以部...
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High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial
Elizabeth Kepreotes, Bruce Whitehead, John Attia, et al.
Summary
Background 背景
Bronchiolitis is the most common lung infection in infants and treatment focuses on management of respiratory distress and hypoxia. High-flow warm humidified oxygen (HFWHO) is increasingly used, but has not been rigorously st...
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JAMA | Original Investigation | CARING FOR THE CRITICALLY ILL PATIENT
Video Laryngoscopy vs Direct Laryngoscopy on Successful First-Pass Orotracheal Intubation Among ICU Patients: A Randomized Clinical Trial
Jean Baptiste Lascarrou, Julie Boisrame-Helms, Arthur Bailly, et al.
JAMA. doi:10.1001/jama.2016.20603
Published online January 24, 2017.
IMPORTANCE 背景
In the intensive care unit (ICU), orotracheal intubation can be associated with increased risk of complications bec...
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