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[JAMA Intern Med发表论文]:生成式人工智能模型与医生临床推理的比较已关闭评论
Research Letter  April 1, 2024 Clinical Reasoning of a Generative Artificial Intelligence Model Compared With Physicians Stephanie Cabral, Daniel Restrepo, Zahir Kanjee, et al JAMA Intern Med. Published online April 1, 2024. doi:10.1001/jamainternmed.2024.0295 Large language models (LLMs) have shown promise in clinical reasoning, but their ability to synthesize clinical encounter data into problem representa...
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[NEJM发表论文]:静脉输注氨基酸保护肾脏功能已关闭评论
ORIGINAL ARTICLE A Randomized Trial of Intravenous Amino Acids for Kidney Protection Giovanni Landoni, Fabrizio Monaco, Lian Kah Ti, et al N Engl J Med Published June 12, 2024 DOI: 10.1056/NEJMoa2403769 Abstract BACKGROUND Acute kidney injury (AKI) is a serious and common complication of cardiac surgery, for which reduced kidney perfusion is a key contributing factor. Intravenous amino acids increase kidney perfusion and recruit renal functional reser...
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[JAMA Netw Open发表论文]:数字健康干预措施与腹腔手术患者安全已关闭评论
Original Investigation  Statistics and Research Methods April 26, 2024 Digital Health Interventions and Patient Safety in Abdominal Surgery: A Systematic Review and Meta-Analysis Artem Grygorian, Diego Montano, Mahdieh Shojaa, et al JAMA Netw Open. 2024;7(4):e248555. doi:10.1001/jamanetworkopen.2024.8555 Key Points Question  Can perioperative telemedicine reduce the incidence of adverse event...
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[ICU Management & Practice]: 建造绿色的ICU已关闭评论
Going Green in the ICU In ICU Fri, 22 Mar 2024 The environmental impact of ICUs was in focus at ISICEM 2024. Nicole Hunfeld, a hospital pharmacist at Erasmus Medical Center in the Netherlands, emphasised the need for a sustainable medication process, particularly noting the heightened waste production during the COVID-19 pandemic.  There is an overwhelming level of plastic waste in the ICU, and its environmental implications need to be addresse...
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[JAMA Netw Open发表论文]:认知训练以减少心脏手术患者的谵妄已关闭评论
Original Investigation  Anesthesiology April 23, 2024 Cognitive Training for Reduction of Delirium in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial Yu Jiang, Yanhu Xie, Panpan Fang, et al JAMA Netw Open. 2024;7(4):e247361. doi:10.1001/jamanetworkopen.2024.7361 Key Points Question  Does preoperative cognitive training reduce the incidence of delirium during recovery from cor...
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[JAMA发表述评]:利用电子病历改进经验性抗生素的使用已关闭评论
Editorial  April 19, 2024 Harnessing the Electronic Health Record to Improve Empiric Antibiotic Prescribing Anurag N. Malani, Preeti N. Malani JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.6554 Approximately half of hospitalized adults in the US receive antibiotics, with pneumonia and urinary tract infection (UTI) being the 2 most frequent indications.1 Estimates suggest about 30% of all antibiotics prescribed in US hospit...
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[JAMA发表论文]:非肿瘤慢性疾病的替代标志物与临床疗效的相关性已关闭评论
Original Investigation  April 22, 2024 Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments Joshua D. Wallach, Samuel Yoon, Harry Doernberg, et al JAMA. Published online April 22, 2024. doi:10.1001/jama.2024.4175 Key Points Question  What is the strength of association between surrogate markers used as primary end points in clinical trials to s...
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[ICU Management & Practice]: 脓毒症患者的血管渗漏已关闭评论
Vascular Leak in Sepsis In Sepsis Tue, 26 Mar 2024 Sepsis remains a major cause of mortality, accounting for nearly 20% of global deaths. Microcirculatory dysfunction, marked by irregular blood flow and increased permeability of blood vessels, is a characteristic feature of sepsis. This dysfunction can lead to tissue swelling and impaired organ function. Endothelial dysfunction, which is also seen in other acute inflammatory disorders like burns, traum...
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[JAMA发表论文]:改进泌尿系感染患者抗生素选择的管理提示已关闭评论
April 19, 2024 Stewardship Prompts to Improve Antibiotic Selection for Urinary Tract Infection: The INSPIRE Randomized Clinical Trial Shruti K. Gohil, Edward Septimus, Ken Kleinman, et al JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.6259 Key Points Question  Can computerized provider order entry prompts that present patient-specific multidrug-resistant organism (MDRO) risk estimates redu...
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[Lancet Microbe发表论文]:西班牙表现为脓毒症或感染性休克的菌血症患者分离得到的大肠杆菌全基因组特征已关闭评论
ARTICLES| VOLUME 5, ISSUE 4, E390-E399, APRIL 2024 Whole-genome characterisation of Escherichia coli isolates from patients with bacteraemia presenting with sepsis or septic shock in Spain: a multicentre cross-sectional study Natalia Maldonado, Inmaculada López-Hernández, Andrea García-Montaner, et al Lancet Microbe 2024; 5: E390-E399 DOI: https://doi.org/10.1016/S2666-5247(23)00369-5 Summary Background Escherichia coli is the most frequent cause...
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