Connecting ICU Data for Better Sepsis Care In Sepsis Wed, 4 Feb 2026 Sepsis remains a leading cause of mortality and long-term disability in intensive care, with outcomes varying widely across hospitals despite advances in technology and repeated guideline updates. One persistent barrier is the fragmentation of clinical data, which limits the ability of clinicians, researchers and health systems to learn systematically from real-world practice. The Eur...

Original Investigation  Public Health Influenza Vaccine and Associated Infection and Death in California, 2024 to 2025 Sophie Zhu, Joshua Quint, Tomás M. León, et al JAMA Netw Open 2026;9;(6):e2617684. doi:10.1001/jamanetworkopen.2026.17684 Key Points Question  Was influenza vaccination associated with protection against laboratory-confirmed influenza during the 2024 to 2025 season, and among infected per...

Original Investigation  Red Blood Cell Exchange Transfusion for Severe Babesiosis STOP-BABESIOSIS Investigators JAMA Intern Med Published Online: March 30, 2026 doi: 10.1001/jamainternmed.2026.0244 Key Points Question  Is red blood cell exchange transfusion (ET) associated with improved clinical outcomes in patients hospitalized with severe babesiosis? Findings  In this multicenter cohort study of 629 patients h...

French Military Transfusion Doctrine for Large-Scale Combat Operations In ICU Wed, 29 Apr 2026 A consensus article presents a revised French military transfusion doctrine tailored for large-scale combat operations (LSCO), addressing the substantial clinical, logistical, and organisational challenges posed by high-intensity warfare. The authors begin by situating the need for reform within the evolving geopolitical context, particularly the resurgenc...

Original Investigation  Anesthesiology Continuous vs Intermittent Postoperative Vital Sign Monitoring: A Cluster Randomized Crossover Trial Ashish K. Khanna, Nathaniel Sean O’Connell, Amit K. Saha, et al JAMA Netw Open 2026;9;(3):e263290. doi:10.1001/jamanetworkopen.2026.3290 Key Points Question  Does continuous vital sign monitoring reduce abnormalities in blood pressure, oxygenation, and heart rate during th...

Research Estimates of global causes of death for children and adolescents aged 5-19 in 2000-24: secondary data analysis using bayesian multinomial logistic regression Hallie Eilerts-Spinelli, Francisco Villavicencio, Jamie Perin, et al BMJ 2026; 393 doi: https://doi.org/10.1136/bmj-2025-088687 (Published 04 June 2026)Cite this as: BMJ 2026;393:e088687 Abstract Objective To estimate cause specific mortality among children and adolescents aged 5-19 years...

Chlorhexidine vs Soap Bathing: Effects on ICU Outcomes In ICU Wed, 29 Apr 2026 An updated systematic review and meta-analysis evaluated whether daily bathing with 2% chlorhexidine gluconate (CHG) improves key clinical outcomes in critically ill patients compared with traditional soap-and-water (SAW) bathing. While CHG has recognised antimicrobial properties and has been widely studied for infection prevention, its broader impact on outcomes such as mor...

Research Global Patterns in Neonatal, Child, and Adolescent Mortality Systematic estimates of global causes of neonatal and under 5 mortality in 2000-24: secondary data analysis using bayesian multinomial logistic regression Jamie Perin, David Prieto-Merino, Astha Wahi, et al BMJ 2026; 393 doi: https://doi.org/10.1136/bmj-2025-088686 (Published 04 June 2026)Cite this as: BMJ 2026;393:e088686 Abstract Objective To estimate cause specific mortality ...

Original Investigation  Infectious Diseases Improving Empiric Antibiotic Selection for Patients With Cancer Hospitalized With Infection: Secondary Analysis of the INSPIRE Cluster Randomized Trials Shruti K. Gohil, Taliser R. Avery, Ken Kleinman, et al JAMA Netw Open 2026;9;(6):e2616611. doi:10.1001/jamanetworkopen.2026.16611 Key Points Question  Can computerized provider order entry (CPOE) prompts with pa...

Research Global Patterns in Neonatal, Child, and Adolescent Mortality Global, regional, and national levels and trends in under 5, infant, and neonatal mortality during 1990-2024 with scenario based projections to 2030: modelling study David Sharrow, Lucia Hug, Yang Liu, et al BMJ 2026; 393 doi: https://doi.org/10.1136/bmj-2025-088684 (Published 04 June 2026)Cite this as: BMJ 2026;393:e088684 Abstract Objective To estimate all cause neonatal, infant, a...