JAMA Diagnostic Test Interpretation September 17, 2021
Interpreting SARS-CoV-2 Test Results
KC Coffey, Daniel J. Diekema, Daniel J. Morgan, et al
JAMA. Published online September 17, 2021. doi:10.1001/jama.2021.16146
A53-year-old woman was referred to the gastroenterology clinic for endoscopy because of a submucosal gastric nodule. She had not received a COVID-19 vaccination and lived in Maryland, which had a 7-day cumulative COVID-19 case rate of 70 per 100 000 individuals at the time of her visit. Review of systems was unremarkable except for intermittent abdominal pain. She had no fever, cough, shortness of breath, difficulty breathing, muscle aches, headache, sore throat, anosmia, dysgeusia, or diarrhea. SARS-CoV-2 reverse transcriptase–polymerase chain reaction (RT-PCR) testing prior to the procedure was performed, in accordance with the American Society of Anesthesiologists Statement on Perioperative Testing1 for monitored anesthesia. Results of preoperative testing are shown in Table 1.
Based on the results, additional history was obtained. The patient reported testing positive for SARS-CoV-2 30 days prior at another hospital. At that time, she had symptoms of dry cough, low-grade fever, and body aches, which resolved after 14 days. Fourteen days before the current presentation, results of a rapid antigen test performed at a local pharmacy were negative for SARS-CoV-2.
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