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ORIGINAL ARTICLE PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock Holger Thiele, Ibrahim Akin, Marcus Sandri, et al N Engl J Med 2017 October 30, 2017DOI: 10.1056/NEJMoa1710261 BACKGROUND 背景 In patients who have acute myocardial infarction with cardiogenic shock, early revascularization of the culprit artery by means of percutaneous coronary intervention (PCI) improves outcomes. However, the majority of patients with cardiogenic shock ha...
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News > Conference News Landmark Trials Deliver Evidence to Rethink Saline Use Ingrid Hein November 02, 2017 TORONTO — Hospitalized patients who receive balanced crystalloid fluids, whether they are critically ill or not, are about 1% less likely to need renal replacement therapy, have persistent renal dysfunction, or die in the hospital than patients who receive saline, two new landmark studies show. 多伦多 - 两项新的重要研究显示,与生理盐水相比,接受平衡盐溶液的...
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Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study David Montaigne, Xavier Marechal, Thomas Modine, et al. Lancet 2017 http://dx.doi.org/10.1016/S0140-6736(17)32132-3 Background 背景 On-pump cardiac surgery provokes a predictable perioperative myocardial ischaemia–reperfusion injury which is associated with poor clinical outcomes. We de...
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Original Investigation October 24/31, 2017 Association of Prehospital Blood Product Transfusion During Medical Evacuation of Combat Casualties in Afghanistan With Acute and 30-Day Survival Stacy A. Shackelford, Deborah J. del Junco, Nicole Powell-Dunford, et al JAMA. 2017;318(16):1581-1591. doi:10.1001/jama.2017.15097 Abstract Importance 背景 Prehospital blood product transfusion in trauma care remains controversial due to poor-quality evidence and cost. Sequential e...
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Research Comparison of postoperative outcomes among patients treated by male and female surgeons: a population based matched cohort study BMJ 2017; 359 doi: https://doi.org/10.1136/bmj.j4366 (Published 10 October 2017) Cite this as: BMJ 2017;359:j4366 Abstract Objective 目的 To examine the effect of surgeon sex on postoperative outcomes of patients undergoing common surgical procedures. 验证外科医生性别对接受常见手术患者的术后预后的影响。 Design 设计 Population based, retr...
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Immediate interruption of sedation compared with usual sedation care in critically ill postoperative patients (SOS-Ventilation): a randomised, parallel-group clinical trial Gerald Chanques, Matthieu Conseil, Claire Roger, et al Lancet Respir Med 2017; 5: 795–805 Published Online September 18, 2017 http://dx.doi.org/10.1016/S2213-2600(17)30304-1 Summary Background 背景 Avoidance of excessive sedation and subsequent prolonged mechanical ventilation in intensive care units (I...
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Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study Brendon P Scicluna, Lonneke A van Vught, Aeilko H Zwinderman, et al Lancet Respir Med 2017 Published Online August 29, 2017 http://dx.doi.org/10.1016/S2213-2600(17)30294-1 Summary Background 背景 Host responses during sepsis are highly heterogeneous, which hampers the identification of patients at high risk of mortality and their selection for targeted therapies. In this ...
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【编者按】:近日,Intensive Care Medicine在线发表了华西医院ICU的研究结果。这一单中心RCT显示,ARDS患者早期使用APRV可显著缩短机械通气时间。在日前结束的欧洲重症医学年会(ESICM LIVES 2017)期间,华西医院的康焰教授作为来自中国大陆的唯一受邀讲者,介绍了这一研究的结果。 Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome. Zhou Y, Jin X, Lv Y, Wang P, Yang Y, Liang G, Wang B, Kang Y. Intens...
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RCTs and Guidelines (FREE ACCESS) Dear loyal ICM reader, We hope you enjoyed LIVES 2017 as much as we did! Whether you were able to join us live in Vienna for our special ICM sessions and critical trial presentations, or you viewed online, we are sure that you would agree that this amazing meeting offered plenty to guide practice, and inspire debate and future clinical research. We are proud to share several published papers from clinical trials presented at the congress ...
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News > Neurology No Benefit of Routine Oxygen in Acute Stroke Sue Hughes September 28, 2017 Routine use of prophylactic oxygen had no benefit or harm in a new large randomized trial in acute stroke patients. 一项新的有关急性卒中患者的大规模随机临床试验显示,常规进行预防性氧疗没有益处。 "This is the largest study of oxygen in acute stroke — the best data we have on this issue, and our results do not support the routine use of low-dose oxygen in nonhypoxic acute strok...
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