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A Contemporary Assessment of Acute Mechanical Ventilation in Beijing: Description, Costs, and Outcomes Yanping Ye, Bo Zhu, Li Jiang, et al Crit Care Med. 2017 Apr 18. doi: 10.1097/CCM.0000000000002360. [Epub ahead of print] OBJECTIVE: 目的 To evaluate the contemporary practice, outcomes, and costs related to mechanical ventilation among ICUs in China. 评价当下中国北京地区ICU中机械通气治疗的实施、患者的转归及花费情况。 DESIGN: 设计 A prospective observational cohort study. ...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Estelle Peronnet et al. Association between mRNA expression of CD74 and IL10 and risk of ICU-acquired infections: a multicentre cohort study. Review ~ Anders Perner et al. Fluid management in acute kidney injury. Review ~ Michael Darmon et al. Diagnostic work-up and specific causes of acute kidney injury. Original ~ Brennan C. Kahan et al. Critical care admission following elective surgery was no...
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Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma (RETIC): a single-centre, parallel-group, open-label, randomised trial Petra Innerhofer, Petra Innerhofer, Dietmar Fries, et al Lancet Hematology 2017 Published: 27 April 2017 DOI: http://dx.doi.org/10.1016/S2352-3026(17)30077-7 Background Effective treatment of trauma-induced coagulopathy is important; however, the optimal therapy is still not known. We aime...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Seven-Day Profile Publication ~ Martin B. Madsen et al. Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial. Review ~ T. Tängdén et al. The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections. Original ~ Frédéric Vargas et al. Intermittent noninvasive ventilation after ...
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Drugs & Diseases > Clinical Trends Clinical Trends for April 2017 Ryan Syrek | April 28, 2017 Each week, we identify one top search term, speculate as to what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, feel free to share them with us on Twitter or Facebook! Clinical Trend of the Week (April 22-28): Rheumatoid Arthritis News about risk and a key drug denial resulted in this week's ...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Emmanuelle Cambau et al. Performance and economic evaluation of the molecular detection of pathogens for patients with severe infections: the EVAMICA open-label, cluster-randomised, interventional crossover trial. Research Agenda ~ Yaseen M. Arabi et al. The intensive care medicine research agenda in nutrition and metabolism. What's New in Intensive Care ~ Antoine Schneider and Marlies Ostermann....
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Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study Yang Wang, Guo-Bao Tian, Rong Zhang, et al Lancet Infect Dis 2017; 17: 390-399 DOI: http://dx.doi.org/10.1016/S1473-3099(16)30527-8 Summary Background 背景 The mcr-1 gene confers transferable colistin resistance. mcr-1-positive Enterobacteriaceae (MCRPE) have attracted substantial medical, me...
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Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study Jingjing Quan, Xi Li, Yan Chen, et al Lancent Infect Dis 2017; 17: 400-410 DOI: http://dx.doi.org/10.1016/S1473-3099(16)30528-X Summary Background 背景 Polymyxin antibiotics are used as last-resort therapies to treat infections caused by multidrug-resistant Gram-negative bacteria. The plasmid-mediated colistin resistance dete...
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Original Investigation April 2017 Comparative Effectiveness of Vancomycin and Metronidazole for the Prevention of Recurrence and Death in Patients With Clostridium difficile Infection Vanessa W. Stevens; Richard E. Nelson; Elyse M. Schwab-Daugherty, et al JAMA Intern Med. 2017;177(4):546-553. doi:10.1001/jamainternmed.2016.9045 Abstract Importance 背景 Metronidazole hydrochloride has historically been considered first-line therapy for patients with mild to moder...
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Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority trial David C Lye, Sophia Archuleta, Sharifah F Syed-Omar, et al. Lancet DOI: http://dx.doi.org/10.1016/S0140-6736(17)30269-6 Summary Background 背景 Dengue is the commonest vector-borne infection worldwide. It is often associated with thrombocytopenia, and prophylactic platelet transfusion is...
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