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High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial Elizabeth Kepreotes, Bruce Whitehead, John Attia, et al Lancet 2017; 389: 930-939 Summary Background 背景 Bronchiolitis is the most common lung infection in infants and treatment focuses on management of respiratory distress and hypoxia. High-flow warm humidified oxygen (HFWHO) is increasingly used, but has...
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Reuters Health Information Early High Protein Intake May Decrease Mortality in ICU Patients With Low Muscle Mass By Rob Goodier March 01, 2017 NEW YORK (Reuters Health) – Delivering high protein nutrition shortly after admission to intensive care may reduce the mortality risk for patients with low muscle mass, a retrospective study suggests. 一项回顾性研究提示,收入ICU后尽快给予高蛋白质营养可能降低肌肉减少患者的死亡风险。 “We found protein intake over days 2 to 4 to be si...
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Medscape > Clinical Trends Clinical Trends for February 2017 Ryan Syrek February 24, 2017 Each week, we identify one top search term, speculate as to what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what’s trending and why, feel free to share them with us on Twitter or Facebook! Clinical Trend of the Week (February 18 - 24): Magnesium Deficiency Speculation into the death of a beloved celebrity resulted in this we...
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Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial Estelle C Nijssen, Roger J Rennenberg, Patty J Nelemans, et al Lancet 2017 (Published 20 February 2017) DOI: http://dx.doi.org/10.1016/S0140-6736(17)30057-0   Background 背景 Intravenous saline is recommended in clinical pract...
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Research Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data Adrian R Martineau, David A Jolliffe, Richard L Hooper, et al. doi: https://doi.org/10.1136/bmj.i6583 (Published 15 February 2017) Cite this as: BMJ 2017;356:i6583 Abstract Objectives To assess the overall effect of vitamin D supplementation on risk of acute respiratory tract infection, and to identify factors modifying this e...
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Research Letter February 21, 2017 Website Characteristics and Physician Reviews on Commercial Physician-Rating Websites Tara Lagu, Katherine Metayer, Michael Moran; et al. JAMA. 2017;317(7):766-768. doi:10.1001/jama.2016.18553 Patients are increasingly seeking information about physicians online. Nearly 60% report that online reviews are important when choosing a physician. Because publicly reported quality data are not reported at the physician level, patients must consul...
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Intravenous zanamivir or oral oseltamivir for hospitalised patients with influenza: an international, randomised, double-blind, double-dummy, phase 3 trial Francisco M Marty, Joan Vidal-Puigserver, Carol Clark, et al Lancet Respir Med Published: 13 January 2017 DOI: http://dx.doi.org/10.1016/S2213-2600(16)30435-0 Background 背景 Neuraminidase inhibitors are effective for the treatment of acute uncomplicated influenza. However, there is an unmet need for intravenous treat...
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Original Investigation February 21, 2017 Effect of Fibrinogen Concentrate on Intraoperative Blood Loss Among Patients With Intraoperative Bleeding During High-Risk Cardiac SurgeryA Randomized Clinical Trial Süleyman Bilecen, Joris A. H. de Groot, Cor J. Kalkman, et al JAMA. 2017;317(7):738-747. doi:10.1001/jama.2016.21037 Abstract 摘要 Importance 背景 Fibrinogen concentrate might partly restore coagulation defects and reduce intraoperative bleeding. 纤维蛋白原可以部...
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High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial Elizabeth Kepreotes, Bruce Whitehead, John Attia, et al. Summary Background 背景 Bronchiolitis is the most common lung infection in infants and treatment focuses on management of respiratory distress and hypoxia. High-flow warm humidified oxygen (HFWHO) is increasingly used, but has not been rigorously st...
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JAMA | Original Investigation | CARING FOR THE CRITICALLY ILL PATIENT Video Laryngoscopy vs Direct Laryngoscopy on Successful First-Pass Orotracheal Intubation Among ICU Patients: A Randomized Clinical Trial Jean Baptiste Lascarrou, Julie Boisrame-Helms, Arthur Bailly, et al. JAMA. doi:10.1001/jama.2016.20603 Published online January 24, 2017. IMPORTANCE 背景 In the intensive care unit (ICU), orotracheal intubation can be associated with increased risk of complications bec...
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