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ORIGINAL ARTICLE Time to Treatment and Mortality during Mandated Emergency Care for Sepsis Christopher W. Seymour, Foster Gesten, Hallie C. Prescott, et al. N Engl J Med May 21, 2017 DOI: 10.1056/NEJMoa1703058 BACKGROUND 背景 In 2013, New York began requiring hospitals to follow protocols for the early identification and treatment of sepsis. However, there is controversy about whether more rapid treatment of sepsis improves outcomes in patients. 2013年,纽约州开始要求所有...
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ORIGINAL ARTICLE Angiotensin II for the Treatment of Vasodilatory Shock Ashish Khanna, Shane W. English, Xueyuan S. Wang, et al. N Engl J Med May 21, 2017 DOI: 10.1056/NEJMoa1704154 BACKGROUND 背景 Vasodilatory shock that does not respond to high-dose vasopressors is associated with high mortality. We investigated the effectiveness of angiotensin II for the treatment of patients with this condition. 对大剂量升压药物无反应的血管舒张性休克伴随很高的病死率。我们研究了这种情...
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Research Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study Akbar K Waljee, Mary A M Rogers, Paul Lin, et al. BMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j1415 (Published 12 April 2017) Cite this as: BMJ 2017;357:j1415 Abstract Objective 背景 To determine the frequency of prescriptions for short term use of oral corticosteroids, and adverse events (sepsis, venous thromboembolism, fractures) associate...
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Abdominal Aortic Aneurysm: Has the Bubble Burst? Rick C Jiang, MBBS, BMedSc, PostGradDipSurgAnat, FRACS; Mark P Brady, PA-C | May 10, 2017 An aneurysm is defined as an increase of greater than 50% from the vessel's original size. For an abdominal aortic aneurysm (AAA), this equates to a diameter of approximately 3 cm. The larger the aneurysm, the greater the risk of rupture. AAAs are commonly diagnosed either incidentally or when they become symptomatic or rupture. Whereas...
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ARTICLES OF THE MONTH ORIGINAL ~ The risk and clinical outcome of candidemia Lortholary O et al. The risk and clinical outcomes of candidemia depending on underlying malignancy. The clinical context of underlying malignancy and hospitalisation in ICU may be relevant to the initial management of candidemia. ARTICLE REVIEW ORIGINAL ~ Fluid administration in severe sepsis and septic shock Marik PE et al. Fluid Administration in Severe Sepsis and Septic shock, Patterns and Out...
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Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial WOMAN Trial Collaborators Lancet 2017 Published: 26 April 2017 DOI: http://dx.doi.org/10.1016/S0140-6736(17)30638-4 Open access funded by Wellcome Trust Background 背景 Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administrati...
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Research Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial) DREAMS Trial Collaborators and West Midlands Research Collaborative BMJ 2017;357:j1455 doi: https://doi.org/10.1136/bmj.j1455 (Published 18 April 2017) Objectives 目的 To determine whether preoperative dexamethasone reduces postoperative vomiting in patients undergoing elective bowel surgery and whether it is associa...
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Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing Jianfang Zhou, Hongcheng Tian, Xueping Du, et al. Crit Care Med. 2017 Apr 18. doi: 10.1097/CCM.0000000000002414. [Epub ahead of print] 下载请点击此处Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing Objective: 研究目的 Information about the epidemiology of sepsis in community residents in China remains scarce and incomplete. The purpose of this study was to describe the occurrence rate an...
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A Contemporary Assessment of Acute Mechanical Ventilation in Beijing: Description, Costs, and Outcomes Yanping Ye, Bo Zhu, Li Jiang, et al Crit Care Med. 2017 Apr 18. doi: 10.1097/CCM.0000000000002360. [Epub ahead of print] OBJECTIVE: 目的 To evaluate the contemporary practice, outcomes, and costs related to mechanical ventilation among ICUs in China. 评价当下中国北京地区ICU中机械通气治疗的实施、患者的转归及花费情况。 DESIGN: 设计 A prospective observational cohort study. ...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Estelle Peronnet et al. Association between mRNA expression of CD74 and IL10 and risk of ICU-acquired infections: a multicentre cohort study. Review ~ Anders Perner et al. Fluid management in acute kidney injury. Review ~ Michael Darmon et al. Diagnostic work-up and specific causes of acute kidney injury. Original ~ Brennan C. Kahan et al. Critical care admission following elective surgery was no...
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