[BMJ发表论文]:新冠肺炎相关低氧性呼吸功能衰竭患者的清醒俯卧位已关闭评论
Research
Efficacy of awake prone positioning in patients with covid-19 related hypoxemic respiratory failure: systematic review and meta-analysis of randomized trials
Jason Weatherald, Ken Kuljit S Parhar, Zainab Al Duhailib, et al
BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-071966 (Published 07 December 2022)Cite this as: BMJ 2022;379:e071966
Abstract
Objective To determine the efficacy and safety of awake prone positioning versus usual care i...
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[NEJM发表论文]:动脉导管未闭的期待疗法或早期布洛芬治疗已关闭评论
ORIGINAL ARTICLE
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus
Tim Hundscheid, Wes Onland, Elisabeth M.W. Kooi, et al
N Engl J Med December 6, 2022DOI: 10.1056/NEJMoa2207418
Abstract
BACKGROUND
Cyclooxygenase inhibitors are commonly used in infants with patent ductus arteriosus (PDA), but the benefit of these drugs is uncertain.
METHODS
In this multicenter, noninferiority trial, we randomly assigned infants with echocardiogra...
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[Lancet Infect Dis发表论文]:奥密克戎变异株对单克隆抗体的耐药已关闭评论
CORRESPONDENCE| VOLUME 23, ISSUE 1, P22-23, JANUARY 01, 2023
Omicron sublineage BQ.1.1 resistance to monoclonal antibodies
Prerna Arora, Amy KempfInga, Nehlmeier Sebastian, et al.
Lancet Infect Dis Published: November 18, 2022
DOI: https://doi.org/10.1016/S1473-3099(22)00733-2
Vaccination represents the key strategy to control the COVID-19 pandemic through induction of neutralising antibody responses and T cell-associated immunity that subst...
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[JAMA Neurol发表论文]:后9/11时代退伍军人颅脑创伤与后续心血管疾病的相关性已关闭评论
Original Investigation
September 6, 2022
Association Between Traumatic Brain Injury and Subsequent Cardiovascular Disease Among Post-9/11–Era Veterans
Ian J. Stewart, Megan E. Amuan, Chen-Pin Wang, et al
JAMA Neurol. 2022;79(11):1122-1129. doi:10.1001/jamaneurol.2022.2682
Key Points
Question What is the association of a traumatic brain injury (TBI) with the subsequent risk of cardiovascular disease in veterans of the recent conflicts in ...
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[Ann Intern Med发表论文]:奈玛特韦与利托那韦治疗早期新冠病毒感染已关闭评论
Original Research13 December 2022
Nirmatrelvir Plus Ritonavir for Early COVID-19 in a Large U.S. Health System: A Population-Based Cohort Study
Scott Dryden-Peterson, Andy Kim, Arthur Y. Kim, et al
Ann Intern Med https://doi.org/10.7326/M22-2141
Abstract
Background:
In the EPIC-HR (Evaluation of Protease Inhibition for Covid-19 in High-Risk Patients) trial, nirmatrelvir plus ritonavir led to an 89% reduction in hospitalization or death among unvaccinated...
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[JAMA Cardiol发表论文]:心脏介入操作时常规超声引导穿刺股动脉已关闭评论
Original Investigation
September 18, 2022
Routine Ultrasonography Guidance for Femoral Vascular Access for Cardiac ProceduresThe UNIVERSAL Randomized Clinical Trial
Sanjit S. Jolly, Sulaiman AlRashidi, Marc-André d’Entremont, et al
JAMA Cardiol. 2022;7(11):1110-1118. doi:10.1001/jamacardio.2022.3399
Key Points
Question Does routine ultrasonography guidance for femoral arterial access for cardiac procedures reduce bleeding or vascular com...
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[JAMA Neurol发表论文]:利妥昔单抗治疗新发全身型重症肌无力的疗效与安全性已关闭评论
Original Investigation
September 19, 2022
Efficacy and Safety of Rituximab for New-Onset Generalized Myasthenia Gravis: The RINOMAX Randomized Clinical Trial
Fredrik Piehl, Ann Eriksson-Dufva, Anna Budzianowska, et al
JAMA Neurol. 2022;79(11):1105-1112. doi:10.1001/jamaneurol.2022.2887
Key Points
Question Is a single infusion with rituximab associated with greater probability of having minimal disease manifestations at 4 months in recent...
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[JAMA Neurol发表论文]:成年自身免疫性脑炎的误诊已关闭评论
Original Investigation
November 28, 2022
Autoimmune Encephalitis Misdiagnosis in Adults
Eoin P. Flanagan, Michael D. Geschwind, A. Sebastian Lopez-Chiriboga, et al
JAMA Neurol. Published online November 28, 2022. doi:10.1001/jamaneurol.2022.4251
Question What diseases are misdiagnosed as autoimmune encephalitis and which factors contribute to misdiagnosis?
Findings In this case series of 107 outpatients misdiagnosed ...
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[JAMA Surg发表论文]:电针疗法与假电针治疗结直肠癌腹腔镜手术后肠梗阻已关闭评论
Original Investigation
November 2, 2022
Electroacupuncture vs Sham Electroacupuncture in the Treatment of Postoperative Ileus After Laparoscopic Surgery for Colorectal Cancer: A Multicenter, Randomized Clinical Trial
Yu Wang, Jing-Wen Yang, Shi-Yan Yan, et al
JAMA Surg. Published online November 2, 2022. doi:10.1001/jamasurg.2022.5674
Key Points
Question In the current medical practice adopting the Enhanced Recovery After Surge...
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[Lancet发表论文]:早期使用莫努匹韦与单纯常规治疗用于具有不良预后风险的新冠肺炎成年患者已关闭评论
RTICLES|ONLINE FIRST
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial
Christopher C Butler, F D Richard Hobbs, Oghenekome A Gbinigie, et al
Lancet AccessPublished:December 22, 2022
DOI:https://doi.org/10.1016/S0140-6736(22)02597-1
Summary
Background
The safety, effectiveness, and cost-effective...
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