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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Fabiana Madotto et al. Resolved versus confirmed ARDS after 24h: Insights from the LUNG SAFE study. Seven-Day Profile Publication ~ Tobias Welte et al. Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomised, placebo-controlled, double-blind, multicentre, phase II trial (CIGMA study). What's New in Intensive Care ~ G...
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Viewpoint April 10, 2018 The Proposal to Lower P Value Thresholds to .005 John P. A. Ioannidis JAMA. 2018;319(14):1429-1430. doi:10.1001/jama.2018.1536 P values and accompanying methods of statistical significance testing are creating challenges in biomedical science and other disciplines. The vast majority (96%) of articles that report P values in the abstract, full text, or both include some values of .05 or less.1 However, many of the claims that these reports highl...
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ORIGINAL ARTICLE Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure Mandeep R. Mehra, Daniel J. Goldstein, Nir Uriel, et al N Engl J Med 2018; 378:1386-1395 DOI: 10.1056/NEJMoa1800866 Abstract BACKGROUND 背景 In an early analysis of this trial, use of a magnetically levitated centrifugal continuous-flow circulatory pump was found to improve clinical outcomes, as compared with a mechanical-bearing axial continuous-flow pump, at 6 months in patient...
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Articles Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study Chen Wang, Jianying Xu, Lan Yang, et al Lancet 2018 Available online 9 April 2018 Summary Background 背景 Although exposure to cigarette smoking and air pollution is common, the current prevalence of chronic obstructive pulmonary disease (COPD) is unknown in the Chinese adult population. We conducted the China Pul...
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News > Medscape Medical News > Conference News > HM 2018 Machine Predicts Inpatient Sepsis 5 Hours Sooner Marcia Frellick April 10, 2018 ORLANDO — Deep machine learning can help predict sepsis in hospitalized patients an average of 5 hours before they meet the clinical definition, new data show. 新的数据显示,深度机器学习能够在住院患者满足临床诊断标准前平均5小时预测全身性感染。 "Every hour delay in antibiotic therapy is associated with a 7% to 8% increase in ...
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Articles Chronic obstructive pulmonary disease in China: a nationwide prevalence study Liwen Fang, Pei Gao, Heling Bao, et al Lancet Respir Med Available online 9 April 2018 https://doi.org/10.1016/S2213-2600(18)30103-6 Summary Background 背景 Because of the rapid change in economic development and lifestyle in China, and the ageing population, concerns have grown that chronic obstructive pulmonary disease (COPD) could become epidemic. An up-to-date nationwide estimat...
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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Signe Riddersholm et al. Organ support therapy in the intensive care unit and return to work: a nationwide, register-based cohort study. Original ~ Yvan Fleury et al. Impact of intravascular thrombosis on failure of radial arterial catheters in critically ill patients: a nested case-control study. Letter ~ Glauco Adrieno Westphal et al. Effect of a 24-h extended visiting policy on delirium in criticall...
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Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study Daniel B Hawcutt, Ben Francis, Daniel F Carr, et al Lancet Respir Med Published: 15 March 2018 DOI: https://doi.org/10.1016/S2213-2600(18)30058-4 Summary Background A serious adverse effect of corticosteroid therapy is adrenal suppression. Our aim was to identify genetic variants affecting susceptibility to corticosteroid-induced adrenal suppression. Methods We enrolled c...
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Health-care system transition in China The Lancet 2018; 391: 1332 Published: 07 April 2018 DOI: https://doi.org/10.1016/S0140-6736(18)30737-2 On March 27, the National Health Commission replaced China's National Health and Family Planning Commission (NHFPC) as the ministry responsible for health. The new commission is now headed by Ma Xiaowei, who was the former deputy head of the dismantled NHFPC. Chinese media have described Xiaowei as the person who understands China's ...
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Research Effect of tai chi versus aerobic exercise for fibromyalgia: comparative effectiveness randomized controlled trial Chenchen Wang, Christopher H Schmid, Roger A Fielding, et al BMJ 2018; 360 doi: https://doi.org/10.1136/bmj.k851 (Published 21 March 2018) Cite this as: BMJ 2018;360:k851 Abstract Objectives 目的 To determine the effectiveness of tai chi interventions compared with aerobic exercise, a current core standard treatment in patients with fibromyalgia, and ...
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