Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Image ~ Sundar Krishnan et al. Unilateral pulmonary venous occlusion caused by a localised pericardial clot. Letter ~ Ayesha Sajjad et al. Psychopathology prior to critical illness and the risk of delirium onset during intensive care unit stay. Review ~ Anders Aneman et al. Advances in critical care management of patients undergoing cardiac surgery. Editorial ~ Theis Lange et al. Prompt admission to the ICU: an i...

Validation of a Host Response Assay, Septicyte™ LAB, for Discriminating Sepsis from SIRS in the ICU Russell R Miller III ; Bert K. Lopansri , John P Burke , et al Am J Respir Crit Care Med 2018 Published Online: April 06, 2018 Rationale: 背景 A molecular test to distinguish between sepsis and systemic inflammation of non-infectious etiology could potentially have clinical utility. 分子检测鉴别全身性感染与非感染因素导致的全身炎症可能有临床意义。 Objectives: 目的 This st...

Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis Derek K Chu, Lisa H-Y Kim, Paul J Young, et al. Lancet 2018; 391: 1693-1705 Summary Background 背景 Supplemental oxygen is often administered liberally to acutely ill adults, but the credibility of the evidence for this practice is unclear. We systematically reviewed the efficacy and safety of liberal versus conservative oxy...

Community-Acquired Pneumonia Visualized on CT Scans but Not Chest Radiographs: Pathogens, Severity, and Clinical Outcomes Cameron P. Upchurch, Carlos G. Grijalva, Richard G. Wunderink, et al. CHEST 2018; 153(3):601-610 BACKGROUND: 背景 The clinical significance of pneumonia visualized on CT scan in the setting of a normal chest radiograph is uncertain. 当胸片正常时，CT扫描可见的肺炎其临床意义并不明确。 METHODS: 方法 In a multicenter prospective surveillance study ...

Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Imaging in Intensive Care Medicine ~ DH. Merdji et al. Vertebral fracture as a complication of cardiopulmonary resuscitation. Letter ~ H. Erhan Dincer et al. The first report of safety and feasibility of transbronchial cryoprobe lung biopsy in ARDS. Seven-Day Profile Publication ~ Xavier Benoit D’Journo et al. Oropharyngeal and nasopharyngeal decontamination with chlorhexidine gluconate in lung cancer surgery: a ...

Original Research: Critical Care Histopathologic Findings in Lungs of Patients Treated With Extracorporeal Membrane Oxygenation Hee Eun Lee, Eunhee S. Yi, Jeffrey T. Rabatin, et al. CHEST 2018; 153(4):825-833 BACKGROUND: 背景 The outcome of extracorporeal membrane oxygenation (ECMO) might be influenced by its complications. Only limited information is available regarding the pathologic consequences of ECMO, especially in the era of modern ECMO technology. 接受ECMO治疗...

Simplifying the use of prognostic information in traumatic brain injury. Part 1: The GCS-Pupils score: an extended index of clinical severity Journal of Neurosurgery Posted online on April 10, 2018 Abstract OBJECTIVE 目的 Glasgow Coma Scale (GCS) scores and pupil responses are key indicators of the severity of traumatic brain damage. The aim of this study was to determine what information would be gained by combining these indicators into a single index and to explore th...

Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Editorial Debate ~ Djillali Annane et al. Are systematic reviews and meta-analyses still useful research? Yes. Editorial Debate ~ Sylvie Chevret et al. Are systematic reviews and meta-analyses still useful research? No. Editorial Debate ~ Morten Hylander Møller et al. Are systematic reviews and meta-analyses still useful research? We are not sure. What's New in Intensive Care ~ Akash Deep et al. Paediatric acute ...

Airway Pressure Release Ventilation in Pediatric Acute Respiratory Distress Syndrome: a Randomized Controlled Trial Saptharishi Lalgudi Ganesan, Muralidharan Jayashree, Sunit Chandra Singhi, et al Am J Respir Crit Care Med 2018 Published Online: April 11, 2018 https://doi.org/10.1164/rccm.201705-0989OC PubMed: 29641221 Rationale: 背景 Though case series describe benefits of Airway pressure release ventilation (APRV), this mo...

Multistate Outbreak of E. coli O157:H7 Infections Linked to Chopped Romaine Lettuce Posted April 13, 2018 2:00 PM EST 概要 病例数 35例 发病    11个州 死亡    0例 住院    22例 召回    无 Highlights Information collected to date indicates that chopped romaine lettuce from the Yuma, Arizona growing region could be contaminated with E. coli O157:H7 and could make people sick. At this time, no common grower, supplier, distributor, or brand has been identified. Adv...