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ARTICLES OF THE MONTH ORIGINAL ~ The risk and clinical outcome of candidemia Lortholary O et al. The risk and clinical outcomes of candidemia depending on underlying malignancy. The clinical context of underlying malignancy and hospitalisation in ICU may be relevant to the initial management of candidemia. ARTICLE REVIEW ORIGINAL ~ Fluid administration in severe sepsis and septic shock Marik PE et al. Fluid Administration in Severe Sepsis and Septic shock, Patterns and Out...
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Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial WOMAN Trial Collaborators Lancet 2017 Published: 26 April 2017 DOI: http://dx.doi.org/10.1016/S0140-6736(17)30638-4 Open access funded by Wellcome Trust Background 背景 Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administrati...
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Research Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial) DREAMS Trial Collaborators and West Midlands Research Collaborative BMJ 2017;357:j1455 doi: https://doi.org/10.1136/bmj.j1455 (Published 18 April 2017) Objectives 目的 To determine whether preoperative dexamethasone reduces postoperative vomiting in patients undergoing elective bowel surgery and whether it is associa...
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Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing Jianfang Zhou, Hongcheng Tian, Xueping Du, et al. Crit Care Med. 2017 Apr 18. doi: 10.1097/CCM.0000000000002414. [Epub ahead of print] 下载请点击此处Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing Objective: 研究目的 Information about the epidemiology of sepsis in community residents in China remains scarce and incomplete. The purpose of this study was to describe the occurrence rate an...
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A Contemporary Assessment of Acute Mechanical Ventilation in Beijing: Description, Costs, and Outcomes Yanping Ye, Bo Zhu, Li Jiang, et al Crit Care Med. 2017 Apr 18. doi: 10.1097/CCM.0000000000002360. [Epub ahead of print] OBJECTIVE: 目的 To evaluate the contemporary practice, outcomes, and costs related to mechanical ventilation among ICUs in China. 评价当下中国北京地区ICU中机械通气治疗的实施、患者的转归及花费情况。 DESIGN: 设计 A prospective observational cohort study. ...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Estelle Peronnet et al. Association between mRNA expression of CD74 and IL10 and risk of ICU-acquired infections: a multicentre cohort study. Review ~ Anders Perner et al. Fluid management in acute kidney injury. Review ~ Michael Darmon et al. Diagnostic work-up and specific causes of acute kidney injury. Original ~ Brennan C. Kahan et al. Critical care admission following elective surgery was no...
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Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma (RETIC): a single-centre, parallel-group, open-label, randomised trial Petra Innerhofer, Petra Innerhofer, Dietmar Fries, et al Lancet Hematology 2017 Published: 27 April 2017 DOI: http://dx.doi.org/10.1016/S2352-3026(17)30077-7 Background Effective treatment of trauma-induced coagulopathy is important; however, the optimal therapy is still not known. We aime...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Seven-Day Profile Publication ~ Martin B. Madsen et al. Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial. Review ~ T. Tängdén et al. The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections. Original ~ Frédéric Vargas et al. Intermittent noninvasive ventilation after ...
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Drugs & Diseases > Clinical Trends Clinical Trends for April 2017 Ryan Syrek | April 28, 2017 Each week, we identify one top search term, speculate as to what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, feel free to share them with us on Twitter or Facebook! Clinical Trend of the Week (April 22-28): Rheumatoid Arthritis News about risk and a key drug denial resulted in this week's ...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Emmanuelle Cambau et al. Performance and economic evaluation of the molecular detection of pathogens for patients with severe infections: the EVAMICA open-label, cluster-randomised, interventional crossover trial. Research Agenda ~ Yaseen M. Arabi et al. The intensive care medicine research agenda in nutrition and metabolism. What's New in Intensive Care ~ Antoine Schneider and Marlies Ostermann....
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