Research Christmas 2018: Look Before You Leap Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial Robert W Yeh, Linda R Valsdottir, Michael W Yeh, et al BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k5094 (Published 13 December 2018) Cite this as: BMJ 2018;363:k5094 Abstract Objective 目的 To determine if using a parachute prevents death or major traumati...

Research Christmas 2018: Food For Thought Effectiveness of a brief behavioural intervention to prevent weight gain over the Christmas holiday period: randomised controlled trial Frances Mason, Amanda Farley, Miranda Pallan, et al BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k4867 (Published 10 December 2018) Cite this as: BMJ 2018;363:k4867 Abstract Objective 目的 To test the effectiveness of a brief beha...

How can a smartphone be used for haemodynamic monitoring? The parameters of the Capstesia app are described. After taking a photo of the arterial waveform on the monitor screen, and cropping it to the signal of interest, the picture is sent to the Capstesia server via a mobile Internet connection. The heart rate and systolic and diastolic arterial pressures are manually entered into the app to determine the cardiac output (CO). After a few seconds, the PPV and CO values (...

Research Association between patient outcomes and accreditation in US hospitals: observational study Miranda B Lam, Jose F Figueroa, Yevgeniy Feyman, et al.BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k4011 (Published 18 October 2018) Cite this as: BMJ 2018;363:k4011M Responses Abstract Objectives 目的 To determine whether patients admitted to US hospitals that are accredited have better outcomes than those admitted to hospitals reviewed through sta...

Intensive Care Medicine ONLINE FIRST THIS WEEK(FREE ACCESS) Original ~ Maryna Masyuk - Prognostic relevance of serum lactate kinetics in critically ill patients Systematic Review ~ Leona Bannon - The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis Editorial ~ Peter Pickkers - Treatment with a polymyxin B filter to capture endot...

Assessment of vocal cord movement by ultrasound in the ICU Zhengshang Ruan, Rongrong Ren, Wenwen Dong, et al Intensive Care Med 2018 Abstract Purpose 目的 Ultrasound can be used to non-invasively and rapidly examine airway conditions, but vocal cord visualization with the traditional approaches is poor. Our aim was to compare the accuracies of front-side transverse-axis ultrasound (FTU), lateral-side longitudinal-axis ultrasound (LLU), and the combination of both approac...

Alleviating inflammation: new inhibitor could treat ARDS in future A newly discovered OGG1 inhibitor has been found to decrease lung inflammation in mice and could in future treat acute respiratory distress syndrome (ARDS), sepsis and autoimmune diseases. The six-year study, by an international team of researchers, is published in Science. The research shows that the OGG1 protein, which is involved in repairing oxidated DNA, signals inflammation. The researchers set out t...

Intensive Care Medicine Erythromycin versus metoclopramide for post-pyloric spiral nasoenteric tube placement: a randomized non-inferiority trial Bei Hu, Xin Ouyang, Liming Lei, et al Intensive Care Med 2018 Abstract Purpose 目的 To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. 验证红霉素辅助重症患者自推进式螺旋型鼻肠管幽门后置管的...

Original Investigation December 4, 2018 Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding Wayne A. Ray, Cecilia P. Chung, Katherine T. Murray, et al JAMA. 2018;320(21):2221-2230. doi:10.1001/jama.2018.17242 Abstract Importance 背景 Anticoagulant choice and proton pump inhibitor (PPI) cotherapy could affect the risk of upper gastrointestinal tract bleeding, a frequent and potential...

Head To Head Patient commentary: Stop hyping artificial intelligence—patients will always need human doctors Michael Mittelman, Sarah Markham, Mark Taylor BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k4669 (Published 07 November 2018) Cite this as: BMJ 2018;363:k4669 If regulated and well implemented, machines that learn have the potential to bring huge benefit to patients, but who wants to receive a terminal diagnosis from a robot? ask Michael Mittelman, Sarah Markham,...