US Preventive Services Task Force  Recommendation Statement August 23/30, 2022 Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement US Preventive Services Task Force JAMA. 2022;328(8):746-753. doi:10.1001/jama.2022.13044 Abstract Importance  Cardiovascular disease (CVD) is the leading cause of morbidity and death in the US and is the cause of more...

PULMONARY VASCULAR: GUIDELINES AND CONSENSUS STATEMENTS| VOLUME 162, ISSUE 1, P213-225, JULY 01, 2022 Thromboprophylaxis in Patients With COVID-19: A Brief Update to the CHEST Guideline and Expert Panel Report Lisa K. Moores, Tobias Tritschler, Shari Brosnahan, et al Chest 2022; 162: 213-225 Published:February 12, 2022 DOI:https://doi.org/10.1016/j.chest.2022.02.006 Background Patients hospitalized with COVID-19 often exhibit markers of a ...

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase–Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections Pranita D. Tamma, Samuel L. Aitken, Robert A. Bonomo, et al Clinical Infectious Diseases 2022; 74(12): 2089-2114 AMPC Β-LACTAMASE–PRODUCING ENTEROBACTERALES Question 1: Which Enterobacterales Should Be Considered at Moderate to High Risk for Clinically Signific...

US Preventive Services Task Force  Recommendation Statement June 21, 2022 Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement US Preventive Services Task Force JAMA. 2022;327(23):2326-2333. doi:10.1001/jama.2022.8970 Abstract Importance  According to National Health and Nutrition Examination Survey data, 52% of surveyed US a...

Research Special Paper Visualising harms in publications of randomised controlled trials: consensus and recommendations Rachel Phillips, Suzie Cro, Graham Wheeler, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-068983 (Published 16 May 2022)Cite this as: BMJ 2022;377:e068983 Abstract  Objective To improve communication of harm in publications of randomised controlled trials via the development of recommendations for visually presen...

JAMA Clinical Guidelines Synopsis May 16, 2022 Antithrombotic Therapy for Venous Thromboembolism Christopher D. Jackson, Adam S. Cifu, Desirée C. Burroughs-Ray JAMA. Published online May 16, 2022. doi:10.1001/jama.2022.7325 Guideline title Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report Developer and funding source American College of Chest Physicians Release date August 2...

On June 30, 2022 the Australian Commission on Safety and Quality in Health Care (the Commission) has released the national Sepsis Clinical Care Standard, in partnership with The George Institute for Global Health. It is an achievement that Australia has reached broad consensus across the health sector, to become one of the first countries to release a nationally agreed quality framework for the recognition and management of sepsis. The standard outlines optimal care...

JAMA Clinical Guidelines Synopsis February 15, 2022 Diagnosis of Lyme Disease David Pitrak, Cynthia T. Nguyen, Adam S. Cifu, et al JAMA. 2022;327(7):676-677. doi:10.1001/jama.2022.0081 Guideline title Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease ...

ICU Management & Practice, Volume 21 - Issue 5, 2021 Management of Acute Arrhythmias in Patients With Cardiac Dysfunction - Update of ESC Guidelines In 2020, the ultra-short acting beta-blocker landiolol was first included in the ESC guidelines with a class I recommendation. The recommendations were based on study results demonstrating the rapid response, efficacy, and safety of this drug. At a recent symposium, during 2021 Heart Failure World Congress, car...

Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine Alexander P. J. Vlaar, Joanna C. Dionne, Sanne de Bruin, et al Intensive Care Medicine  2021; 47: 1368-1392 Transfusion support in massively bleeding, critically ill adults Part 1: massively bleeding patients 1. Transfusion ratios We suggest use of high-ratio transfusion strategies (at least one unit plasm...