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COVID-19: Risk Score to Predict Critical Illness The coronavirus disease (COVID 19) continues to create havoc around the globe. Millions of people have been infected with the virus and thousands have died. The infection is spread via droplet particles. Many infected patients remain asymptomatic; others develop a mild upper respiratory infection-like illness and some develop a serious lung infection that requires admission to the ICU. COVID-19 cases that are of a severe...
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Is COVID-19 Pneumonia ARDS or Not? COVID-19 pneumonia meets the ARDS Berlin definition. However, it is a specific disease with peculiar phenotypes. The primary characteristic is the dissociation between the severity of the hypoxaemia and the maintenance of respiratory mechanics. Patients with respiratory compliance that is lower or higher than the median value experience severe hypoxaemia. In a recent editorial published in Critical Care, the authors propose ...
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COVID-19: Quarantine Measures, Laws and Limits COVID-19 continues to spread, and governments across the globe have imposed quarantines and travel bans. China locked down its cities, Italy imposed restrictions throughout the country, and the US and Canada have enforced self-quarantine. The US has banned the entry of travellers from China, Iran, and most of Europe, while many other countries have implemented heavy screening protocols. However, despite these quarantine me...
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ICU Management & Practice, Volume 20 - Issue 1, 2020 COVID-19: Masks in Intensive Care Units With the number of COVID-19 cases increasing in the intensive care units, there is a high risk of infection for healthcare professionals. What kind of masks can be used and what are the most effective strategies to protect against airborne particles? Currently, there is an increasing number of patients in the intensive care units (ICUs) due to COVID-19 all over t...
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ICU Management & Practice, Volume 20 - Issue 1, 2020 Adaptive Strategies for Intensive Care During the Spread of COVID-19: The Brussels Experience Structured interventions and bottom-up initiatives at a tertiary Intensive Care Unit in Brussels, Belgium. Introduction Optimisation of medical response to no-notice events has been an important focus of research in the field of disaster medicine (Debacker et al. 2016). However, evidence-driven development ...
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ICU Management & Practice, Volume 20 - Issue 1, 2020 Tracheal Intubation in the ICU Making tracheal intubation safe for both patients and their health care providers. Introduction COVID-19 is a newly recognised viral infection which first appeared in Wuhan, China in late 2019. It is caused by a novel Coronavirus, Severe Acute Respiratory Syndrome-CoronaVirus-2. For the most part it results in a mild, self-limiting flu-like illness but unfortunately, s...
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COVID-19: Universal Masking in Hospitals The SARS-Cov-2 pandemic has all healthcare institutions scrambling for protocols to prevent virus transmission. The name of the game is to protect both patients and healthcare providers from the virus. However, every hospital has its protocol with respect to precautionary measures that have been undertaken to prevent transmission. While some hospitals advocate universal masking, other institutions are more selective and only enc...
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Hydroxychloroquine and QT Prolongation As the healthcare community attempts to deal with the coronavirus disease (COVID-19), there is an intense effort to develop an effective treatment strategy. While research on the development of a vaccine continues, clinicians have been forced to use treatments that lack robust clinical evidence. With many patients succumbing to acute respiratory distress syndrome, multi-organ failure, severe pneumonia, and a variety of cardiac com...
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Association of ACE Inhibitors and COVID-19 Severity or Risk of Death The COVID-19 pandemic has resulted in a significant number of deaths worldwide. Clinicians are still unclear as to who might be more susceptible to the infection and the factors associated with increased mortality. Laboratory data have shown that the angiotensin-converting enzyme-2 (ACE-2) serves as the receptor for severe acute respiratory syndrome coronavirus to gain entry into airway cells. Thus, a...
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Convalescent Plasma for COVID-19 Deaths from COVID-19 continue to increase, forcing clinicians to try therapies that are not backed by strong clinical evidence.  One such treatment is convalescent plasma. This century old treatment has been used on and off during infectious disease outbreaks. In 1893, German scientists used this strategy to treat patients with diphtheria. In 1901, Emil von Behring won the first Nobel Prize in Medicine or Physiology for research...
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