研究点评 | 中国病理生理学会危重病医学专业委员会
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Fluid Challenge: Its Impact on Fluid Responsiveness The fluid challenge is considered the gold standard for diagnosis of fluid responsiveness. A new systematic review finds that the duration of the fluid infusion in a fluid challenge has a significant influence on fluid responsiveness – i.e., a rapid infusion increases the proportion of patients with a positive response. However, the type and volume of fluid or the time of assessment does not appear to have any effect o...
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[编者按]:2017年4月8日,我们在网站上介绍了JAMA在线发表的RCT结果:肺保护性通气基础上肺复张对术后肺部并发症的影响。近日,JAMA刊登了两封读者来信,对该研究结果提出了自己的看法。 Comment & Response August 15, 2017 Alveolar Recruitment Strategies After Cardiac Surgery—Reply Marcelo B. P. Amato, Marcia S. Volpe, Ludhmila A. Hajjar JAMA. 2017;318(7):668-669. doi:10.1001/jama.2017.8697 In Reply Drs Li and Shi raised concerns about which of our study groups actually provided...
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Global Study: Most ICU Patients Underfed A large international multicentre cohort study shows that most of the patients are underfed during their ICU stay. In their findings published in the journal Clinical Nutrition, researchers say most of the patients in intensive care are receiving the same amount of calories regardless of their condition, patient's well-being is not satisfied, and delayed nutrition is more frequent. The findings show poor adherence to nutritional gu...
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[编者按]:2017年4月8日,我们在网站上介绍了JAMA在线发表的RCT结果:肺保护性通气基础上肺复张对术后肺部并发症的影响。近日,JAMA刊登了两封读者来信,对该研究结果提出了自己的看法。 Comment & Response August 15, 2017 Alveolar Recruitment Strategies After Cardiac Surgery Guohui Li, Xueyin Shi JAMA. 2017;318(7):667. doi:10.1001/jama.2017.8689 To the Editor Dr Costa Leme and colleagues1 reported that an intensive alveolar recruitment strategy resulted in less-severe pulmonary...
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[编者按]: 纵观国际医学领域,近年来也不乏各种运动造势,推出各种理念,最终只是空欢喜一场。相应的例证如他汀类药物的神奇疗效。肠道菌丛的无限应用范围以及与各种急性慢性疾病的普遍相关性,未来很有可能成为又一经典范例。精准医学也是近年的宠儿。事实上,在精准医学盛行其道的今天,仍然有部分专家保持了清醒的头脑(学会网址既往也转载JAMA述评介绍相应观点)。本文虽然并不直接与重症医学领域相关,但文中观点对我们可能仍有帮助。 From The JAMA Network August 1, 2017 Viral Testing for Pediatric ...
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Clinical trial research in focus: rethinking trials in sepsis David Grimaldi, Jean-Louis Vincent Lancet Respir Med 2017; 8: 610-611 Published: August 2017 DOI: http://dx.doi.org/10.1016/S2213-2600(17)30268-0 Sepsis is a frequent condition, defined as life-threatening organ dysfunction associated with a severe infection.1 Over the past three decades, progress in understanding of the pathophysiology of sepsis has led to the development of a large number of potential new the...
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【编者按】:JAMA杂志近期发表的文章显示,2011年全国去甲肾上腺素供应短缺与感染性休克患者病死率升高具有显著相关性。网站曾于4月6日介绍了该文摘要及主要结果。近日,MEDSCAPE刊登了Greg Martin的简短评论。我们在此刊出,以飨读者。 News & Perspective > Viewpoints COMMENTARY Drug Shortages and Septic Shock: Not a Good Mix Greg Martin, MD June 28, 2017 Association Between US Norepinephrine Shortage and Mortality Among Patients With Septic Shock Vail E, Gershengorn HB, Hua M, ...
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Medical News & Perspectives July 19, 2017 In Treating Sepsis, Questions About Timing and Mandates Jennifer Abbasi JAMA. Published online July 19, 2017. doi:10.1001/jama.2017.7997 In 2012, Rory Staunton, a 12-year-old boy from Queens, New York, died from sepsis after his pediatrician and an emergency department (ED) physician reportedly misinterpreted warning signs—a high fever and vomiting, but also a cut on his arm, and severe leg pain—as an intestinal illness and...
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[编者按]:自从各大医院的比拼指标从床位数及总收入转变为发表论文数后,在高影响因子杂志发表论文的现金奖励已经成为业内共识。这种政策的出台的确鼓励临床医生投入更多精力从事科研,但是,现金奖励政策真的能够催生好的科研吗?这一政策对科研工作有何潜在影响? Business Impact The Truth about China’s Cash-for-Publication Policy The first study of payments to Chinese scientists for publishing in high-impact journals has serious implications for the future of research by Emerging Technolog...
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