Recommended Reading from the University of Ottawa Nephrology Fellows David Massicotte-Azarniouch, Syed Obaid Amin, Caitlin Hesketh and Edward G. Clark AJRCCM Articles in Press. Published on 02-May-2017 as 10.1164/rccm.201611-2375RR Zarbock et al. Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial. JAMA (6) Reviewed by Syed Obaid Amin The Effect of Early vs...

Recommended Reading from the University of Ottawa Nephrology Fellows David Massicotte-Azarniouch, Syed Obaid Amin, Caitlin Hesketh and Edward G. Clark AJRCCM Articles in Press. Published on 02-May-2017 as 10.1164/rccm.201611-2375RR Gaudry S, et al.; Initiation strategies for renal-replacement therapy in the intensive care unit. N Engl J Med (1) Reviewed by David Massicotte-Azarniouch Meta-analyses of mainly observational studies have shown relatively earlier initiation of...

Comment & Response May 9, 2017 Use of the qSOFA Score in the Emergency Department—Reply Yonathan Freund, Ben Bloom, Bruno Riou JAMA. 2017;317(18):1910. doi:10.1001/jama.2017.3511 In Reply Dr Scheer and colleagues have 3 concerns about our study: questionable definitions, inconsistent methods, and a data set that includes missing values. The definition of “severe sepsis” that we used may not capture all patients in this category, particularly those with organ dysfunc...

Comment & Response May 9, 2017 Use of the qSOFA Score in the Emergency Department Christian S. Scheer, Sven-Olaf Kuhn, Sebastian Rehberg JAMA. 2017;317(18):1909-1910. doi:10.1001/jama.2017.3504 To the Editor The quick Sequential Organ Failure Assessment (qSOFA) score is much simpler and faster to accomplish than other screening tools and does not require results from laboratory analyses or invasive monitoring. It represents a useful score for the emergency departm...

News & Perspective > Critical Issues Which Score to Use When Screening for Sepsis on the Wards Aaron B. Holley, MD April 21, 2017 Quick Sepsis-Related Organ Failure Assessment, Systemic Inflammatory Response Syndrome, and Early Warning Scores for Detecting Clinical Deterioration in Infected Patients Outside the Intensive Care Unit Churpek MM, Snyder A, Han X, et al Am J Respir Crit Care Med. 2017;195:906-911 Background 背景 The Sepsis-3 consensus statement recom...

Blood Donor Age, Sex Do Not Affect Outcomes After All Diana Swift April 27, 2017 Blood donor age and sex are not associated with recipient survival, and are therefore not relevant to donated blood allocation, according to a Scandinavian study of almost 1 million transfusions. 斯堪的纳维亚一项对将近100万名输血患者的研究显示，献血者年龄和性别与接受输血患者的生存率并不相关，因此，在分配血液时无需考虑上述因素。 The new findings, published online April 24 in JAMA Internal M...

Original Investigation April 24, 2017 Association of Donor Age and Sex With Survival of Patients Receiving Transfusions Gustaf Edgren, Henrik Ullum, Klaus Rostgaard, et al JAMA Intern Med. Published online April 24, 2017. doi:10.1001/jamainternmed.2017.0890 Importance 背景 Following animal model data indicating the possible rejuvenating effects of blood from young donors, there have been at least 2 observational studies conducted with humans that have investigated w...

Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Neto AS, et al. Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual pa...

Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Dickson et al. Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome. Nat Microbio (8) Reviewed by Daniel S. Jones Acute respiratory distress syndrome (ARDS) is...

Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Kor DJ. Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial. JAMA (1) Reviewed by Kevin C. Ma Acute respiratory distress syndr...