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Medscape Pulmonary Medicine > Viewpoints COMMENTARY A Snapshot of CAP in the United States Nicholas Gross, MD, PhD October 07, 2015 Community-Acquired Pneumonia Requiring Hospitalization Among US Adults Jain S, Self WH, Wunderink RG, et al; CDC EPIC Study Team N Engl J Med. 2015;373:415-427 Study Summary Community-acquired pneumonia (CAP) is a common cause of hospitalization and death. It is important, therefore, to know the frequency of CAP and identity the most impor...
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EPO in traumatic brain injury: two strikes…but not out?  David K Menon, Andrew I R Maas Lancet 2015 Published Online October 7, 2015 http://dx.doi.org/10.1016/S0140-6736(15)00387-6 Despite past failures [1]  the promise of clinical neuroprotection in traumatic brain injury continues to drive the assessment of new compounds. The latest of these compounds is erythropoietin, a haemopoietic growth factor from the type 1 cytokine superfamily, which, through several non-haemopo...
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High-FlowNasal Oxygen Therapy for Postextubation Acute Hypoxemic Respiratory Failure JAMA 2015; 314: 1644-1645 In Reply作者回答: We agree with Drs Girault and Rabbat that our eligibility criteria may have led to the inclusion of patients with different severities of respiratory failure (eg, mild postextubation respiratory failure and moderate to severe respiratory failure) in extubated patients. According to their suggestion, we reanalyzed the data according to the diffe...
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Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial Alistair Nichol, Craig French, Lorraine Little, Samir Haddad, Jeff rey Presneill, Yaseen Arabi, Michael Bailey, D James Cooper, Jacques Duranteau, Olivier Huet, Anne Mak, Colin McArthur, Ville Pettil., Markus Skrifvars, Shirley Vallance, Dinesh Varma, Judy Wills, Rinaldo Bellomo, for the EPO-TBI Investigators and the ANZICS Clinical Trials Group* Lancet 2015 Published Online Octo...
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Editorial | October 27, 2015 The Changing Landscape of Noninvasive Ventilation in the Intensive Care Unit Bhakti K. Patel, MD; John P. Kress, MD JAMA. 2015;314(16):1697-1699. doi:10.1001/jama.2015.12401 Traditionally, endotracheal intubation has been used as a treatment for patients with respiratory failure who require mechanical ventilation. Although intubation can be lifesaving, it is also associated with significant morbidity.1 Immunocompromised patients with acute h...
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Skin antisepsis with chlorhexidine–alcohol versus povidone iodine–alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial Olivier Mimoz, Jean-Christophe Lucet, Thomas Kerforne, Julien Pascal, Bertrand Souweine, Véronique Goudet, Alain Mercat, Lila Bouadma, Sigismond Lasocki, Serge Alfandari, Arnaud Friggeri, Florent Wallet, Nicolas Allou, Sté...
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ARTICLES OF THE MONTH ORIGINAL ~ Geographical Variation in Intensive Care Use? Vestergaard et al. Geographical Variation in Use of Intensive Care: A Nationwide Study. An analysis of geographical variation in use of ICUs within a homogeneous healthcare system. ARTICLE REVIEW ORIGINAL ~ Recovery in elderly ICU patients Heyland  et al. Recovery After Critical Illness in Patients Aged 80 Years or Older: A Multicentre Prospective Observational Cohort Study. This multicentr...
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Acute kidney injury in China: a cross-sectional survey Li Yang, Guolan Xing, Li Wang, Yonggui Wu, Suhua Li, Gang Xu, Qiang He, Jianghua Chen, Menghua Chen, Xiaohua Liu, Zaizhi Zhu, Lin Yang*, Xiyan Lian, Feng Ding, Yun Li, Huamin Wang, Jianqin Wang, Rong Wang, Changlin Mei, Jixian Xu, Rongshan Li, Juan Cao, Liang Zhang, Yan Wang, Jinhua Xu, Beiyan Bao, Bicheng Liu, Hongyu Chen, Shaomei Li, Yan Zha, Qiong Luo, Dongcheng Chen, Yulan Shen, Yunhua Liao, Zhengrong Zhang, Xianqi...
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High-FlowNasal Oxygen Therapy for Postextubation Acute Hypoxemic Respiratory Failure JAMA 2015; 314: 1644 To the Editor致编辑: Dr Stéphan and colleagues [1] demonstrated, in a large multicenter noninferiority randomized trial, that high-flow nasal oxygen could be as effective as noninvasive ventilation in preventing or treating postextubation acute hypoxemic respiratory failure after cardiothoracic surgery. High-flow nasal oxygen is an emerging oxygenation technique with...
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