[Lancet发表论文]:英国幼年下呼吸道感染与成年过早死于呼吸道疾病已关闭评论
ARTICLES|ONLINE FIRST
Early childhood lower respiratory tract infection and premature adult death from respiratory disease in Great Britain: a national birth cohort study
James Peter Allinson, Nishi Chaturvedi, Andrew Wong, et al.
Lancet Published:March 07, 2023
DOI:https://doi.org/10.1016/S0140-6736(23)00131-9
Summary
Background
Lower respiratory tract infections (LRTIs) in early childhood are known to influence lung development and lifelong lung hea...
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[NEJM发表述评]:肺动脉高压治疗的持续进步已关闭评论
EDITORIAL
Continued Progress in Therapy for Pulmonary Arterial Hypertension
Darren B. Taichman, Jane A. Leopold, Greg Elliott
N Engl J Med March 6, 2023DOI: 10.1056/NEJMe2300324
Pulmonary arterial hypertension is a devastating disorder characterized by precapillary pulmonary hypertension not caused by respiratory disease, obstruction of the pulmonary arteries, or certain less-common conditions. Idiopathic pulmonary arterial hypertension, heritable pulmonary ar...
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Intensive Care Medicine在线免费阅读已关闭评论
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LATEST ARTICLES
OriginalDaily point-of-care ultrasound-assessment of central venous catheter-related thrombosis in critically ill patients: a prospective multicenter studyWu C. et al.
OPEN ACCESSOptimal oxygen and mean arterial blood pressure targets after cardiac arrestSkrifvars M., Bray J. and Hassager C.
Understanding the DiseaseHigh-risk pulmonary embolism in the intensive care unitHelms J., Carrier M. and Klok F.A.
Recent adv...
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[NEJM发表论文]:Sotatercept治疗肺动脉高压的3期临床试验已关闭评论
ORIGINAL ARTICLE
Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension
Marius M. Hoeper, David B. Badesch, H. Ardeschir Ghofrani, et al
N Engl J Med March 6, 2023DOI: 10.1056/NEJMoa2213558
Abstract
BACKGROUND
Pulmonary arterial hypertension is a progressive disease involving proliferative remodeling of the pulmonary vessels. Despite therapeutic advances, the disease-associated morbidity and mortality remain high. Sotatercept is a ...
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[ICU Management & Practice]: 改进ICU患者的血流动力学管理:去儿茶酚胺化与减少心脏应激已关闭评论
ICU Management & Practice, Volume 22 - Issue 5, 2022
Improving Haemodynamic Management of ICU Patients: Decatecholaminisation & Cardiac Stress Reduction
A summary of a symposium organised by AOP Health with presentations from Ricard Ferrer, Vall d’Hebron University Hospital, Barcelona, Spain; Bruno Levy, Centre Hospitalier Universitaire de Nancy, CHU Nancy · Réanimation Médicale Brabois, France; and Michael Fries, St. Vincenz Krankenhaus Limburg, Depart...
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[JAMA发表论文]:分娩中使用阿奇霉素或安慰剂对新生儿脓毒症及死亡的影响已关闭评论
Original Investigation
March 7, 2023
Effect of Intrapartum Azithromycin vs Placebo on Neonatal Sepsis and Death: A Randomized Clinical Trial
Anna Roca, Bully Camara, Joel D. Bognini, et al
JAMA. 2023;329(9):716-724. doi:10.1001/jama.2022.24388
Key Points
Question Does azithromycin administered orally during labor reduce neonatal sepsis and mortality?
Findings This randomized trial in West Africa included 11 983 bi...
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[BMJ发表论文]:美国手术预后的种族与性别差异已关闭评论
Research
Inequities in surgical outcomes by race and sex in the United States: retrospective cohort study
Dan P Ly, Mariah B Blegen, Melinda M Gibbons, et al
BMJ 2023; 380 doi: https://doi.org/10.1136/bmj-2022-073290 (Published 01 March 2023)Cite this as: BMJ 2023;380:e073290
Abstract
Objective To assess inequities in mortality by race and sex for eight common surgical procedures (elective and non-elective) across specialties in the United States.
D...
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[Lancet Respir Med发表述评]:是否需要3年时间才知道瑞德西韦能够挽救生命?已关闭评论
COMMENT|ONLINE FIRST
Remdesivir saves lives. Were 3 years needed to learn that?
Andre C Kalil
Lancet Respir Med Published: February 21, 2023
DOI:https://doi.org/10.1016/S2213-2600(23)00036-X
In The Lancet Respiratory Medicine, Alain Amstutz and colleagues1address a 3-year-old controversy: does remdesivir reduce mortality in patients hospitalised for COVID-19?
Remdesivir is a viral RNA polymerase inhibitor that was evaluated in patients hospitalised for C...
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[ICU Management & Practice]: 疲劳对麻醉科医生的影响已关闭评论
Impact of Fatigue on Anaesthesia Providers
Fatigue is being recognised as a workplace hazard of increasing concern. It is a significant problem for anaesthesiologists who have long working hours and irregular schedules. Fatigue negatively impacts vigilance, communication, and teamwork and shows decreased performance during psychomotor testing. However, its impact on real-life performance is uncertain.
Fatigue is a complex issue with many definitions proposed in ...
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[Lancet Rheumatol发表论文]:免疫球蛋白、糖皮质激素或联合治疗儿童多系统炎症综合征已关闭评论
ARTICLES|ONLINE FIRST
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study
Samuel Channon-Wells, Ortensia Vito, Andrew J McArdle, et al.
Lancet Rheumatol Published:February 14, 2023
DOI:https://doi.org/10.1016/S2665-9913(23)00029-2
Summary
Background
Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory condition associated with SARS-CoV-2 infe...
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