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Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery D.J. Hausenloy, L. Candilio, R. Evans, C. Ariti, D.P. Jenkins, S. Kolvekar, R. Knight, G. Kunst, C. Laing, J. Nicholas, J. Pepper, S. Robertson, M. Xenou, T. Clayton, and D.M. Yellon, for the ERICCA Trial Investigators* N Engl J Med 2015;373:1408-17. DOI: 10.1056/NEJMoa1413534 BACKGROUND背景 Whether remote ischemic preconditioning (transient ischemia and reperfusion of the arm) can improve clinical outcomes in...
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Medscape Medical News Apple ResearchKit Data to Be Used in Three Clinical Studies Ken Terry October 16, 2015   根据苹果新闻发布会报道,三个大型研究型医学中心—Duke,Johns Hopkins以及Oregon Health & Science University—宣布将在自闭症、癫痫和黑色素瘤的研究中使用苹果的研究应用(ResearchKit)。 ResearchKit是一个开源平台,允许医学研究人员在患者许可的情况下通过iPhone和iPad的移动医疗(m-health)应用及设备收集数据。根据苹果公司公布的数据,超过100,000名患者已经参加了超过50项Res...
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A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery P. Meybohm, B. Bein, O. Brosteanu, J. Cremer, M. Gruenewald, C. Stoppe, M. Coburn, G. Schaelte, A. Böning, B. Niemann, J. Roesner, F. Kletzin, U. Strouhal, C. Reyher, R. Laufenberg‑Feldmann, M. Ferner, I.F. Brandes, M. Bauer, S.N. Stehr, A. Kortgen, M. Wittmann, G. Baumgarten, T. Meyer‑Treschan, P. Kienbaum, M. Heringlake, J. Schön, M. Sander, S. Treskatsch, T. Smul, E. Wolwender, T. Schilling, G. Fue...
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Medscape Medical News Fluid Management: Buffered Crystalloid No Benefit vs Saline Diana Phillips October 12, 2015 Fluid therapy with a buffered crystalloid solution does not reduce the risk for acute kidney injury (AKI) or kidney failure relative to saline among intensive care unit (ICU) patients who need intravenous fluids, according to a new study. 根据一项新发表的研究结果,与生理盐水相比,采用平衡盐溶液进行液体治疗并不降低需要静脉输液的ICU患者急性肾损伤(AKI)或肾功能衰...
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Getting Warmer on Critical Care for Head Injury Claudia S. Robertson, M.D., and Allan H. Ropper, M.D. This article was published on October 7, 2015, at NEJM.org. DOI: 10.1056/NEJMe1511174 Unlike the successes for almost every other organ, resuscitation of the brain has been a fitful pursuit, punctuated by enthusiasm in early trials and subsequent disappointment. Even hypothermia after cardiac arrest, a seeming success, was tempered by a study in the Journal  showing that ...
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[编者按]:在刚刚结束的欧洲危重病医学会年会(ESICM LIVES 2015)期间,组委会精心挑选了近期在线发表的诸多临床研究,分别在Clinical Trials in Intensive Care, President Session以及Hot Topic Session进行介绍。这些研究结果分别在线发表于JAMA, N Engl J Med以及Lancet等杂志。我们将对其中部分研究及其述评进行简单介绍。 Acetaminophen for Fever in Critically Ill Patients with Suspected Infection Paul Young, M.D., Manoj Saxena, M.D., Rinaldo Bellomo, M.D., Ross Freebairn, M.D., Naomi Hammond,...
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[编者按]:在刚刚结束的欧洲危重病医学会年会(ESICM LIVES 2015)期间,组委会精心挑选了近期在线发表的诸多临床研究,分别在Clinical Trials in Intensive Care, President Session以及Hot Topic Session进行介绍。这些研究结果分别在线发表于JAMA, N Engl J Med以及Lancet等杂志。我们将对其中部分研究及其述评进行简单介绍。 Hypothermia for Intracranial Hypertension after Traumatic Brain Injury Peter J.D. Andrews, M.D., M.B., Ch.B., H. Louise Sinclair, R.G.N., M.Sc., Aryelly Rodriguez, M.Sc., Br...
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ARTICLES OF THE MONTH ORIGINAL ~ Protocol-directed weaning associated with beneficial clinical outcomes Zhu et al. Effect of a quality improvement programme on weaning from mechanical ventilation: a cluster randomised trial. This prospective, cluster randomised controlled trial in fourteen ICUs in Beijing, China, sought to evaluate the efficacy of a quality improvement (QI) programme for protocol-directed weaning from mechanical ventilation.   REVIEW ~ Biomarkers vs....
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Systemic inflammatory response syndrome criteria in defining severe sepsis. ICM Index Number: 22/050 Authors: Kaukonen K-M, Bailey M, Pilcher D, Cooper DJ, Bellomo R. Reference: N Engl J Med 2015; doi:10.1056/NEJMoa1415236 © Massachusetts Medical Society. ICM ABSTRACT Objective To determine the sensitivity, face validity, and construct validity of the current definition of severe sepsis.  Introduction The current consensus definition of severe sepsis requires suspected or...
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[编者按]:在刚刚结束的欧洲危重病医学会年会(ESICM LIVES 2015)期间,组委会精心挑选了近期在线发表的诸多临床研究,分别在Clinical Trials in Intensive Care, President Session以及Hot Topic Session进行介绍。这些研究结果分别在线发表于JAMA, N Engl J Med以及Lancet等杂志。我们将对其中部分研究及其述评进行简单介绍。 Editorial | October 07, 2015 The Changing Landscape of Noninvasive Ventilation in the Intensive Care Unit Bhakti K. Patel, MD; John P. Kress, MD JAMA. Published online Oct...
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