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Medical News & Perspectives May 22/29, 2018 Taking a Closer Look at the Biomarker Test for Mild Traumatic Brain Injury Rebecca Voelker, MSJ JAMA. 2018;319(20):2066-2067. doi:10.1001/jama.2018.4644 Not long after a first-of-its-kind blood test received approval to evaluate patients with mild traumatic brain injury, headlines dubbed it a “concussion test.” But experts in biomarkers are clarifying certain misconceptions about what the test can and can’t reveal. “It’s ...
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Original Investigation June 5, 2018 Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration Lisa M. Askie, Brian A. Darlow, Neil Finer, et al. JAMA. 2018;319(21):2190-2201. doi:10.1001/jama.2018.5725 Abstract Importance 背景 There are potential benefits and harms of hyperoxemia and hypoxemia for extremely preterm infants receiving more vs less supplemental...
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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) What's New in Intensive Care ~ R. T. Mankowski et al. Long-term impact of sepsis on cardiovascular health. Original ~ Mieke Deschepper et al. Effects of chlorhexidine gluconate oral care on hospital mortality: a hospital-wide, observational cohort study. Review ~ Antoine Vieillard-Baron et al. Diagnostic workup, etiologies and management of acute right ventricle failure. Review ~ Spyros D. Mentzelopoulos et al....
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Original Investigation May 8, 2018 Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis William F. McIntyre, Kevin J. Um, Waleed Alhazzani, et al JAMA. 2018;319(18):1889-1900. doi:10.1001/jama.2018.4528 Abstract Importance Vasopressin is an alternative to catecholamine vasopressors for patients with distributive shock—a condition due to ex...
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News > Medscape Medical News > Conference News > ATS 2018 Discharge From a Crowded Hospital Ward Ups Readmission Risk Ingrid Hein May 21, 2018 Patients discharged from crowded hospital wards are more likely to be readmitted to the hospital in the subsequent 30 days, new data show. The three strongest predictors of a patient's readmission "are all modifiable, ward-level factors," said lead researcher Rachel Kohn, MD, from the University of Pennsylvania in Philad...
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Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial Nikola Sprigg, Katie Flaherty, Jason P Appleton, et al. Lancet  Published: 16 May 2018 DOI: https://doi.org/10.1016/S0140-6736(18)31033-X Summary Background Tranexamic acid can prevent death due to bleeding after trauma and post-partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and ...
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News > Medscape Medical News Add-on Vasopressin May Lower AF Risk in Distributive Shock Patrice Wendling May 14, 2018 Patients in distributive shock appear to have a lower risk for atrial fibrillation when vasopressin is added to catecholamine vasopressors, but its effect on other outcomes are mixed, according to a new systematic review and meta-analysis. Based on pooled data from 13 studies at low risk of bias, the addition of vasopressin was associated with a 33% r...
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Perspective > Medscape Neurology > Viewpoints COMMENTARY Additions to Glasgow Coma Scale Aid Prognosis in TBI Laurie Barclay, MD May 15, 2018 Simplifying the Use of Prognostic Information in Traumatic Brain Injury. Part 1: The GCS-Pupils Score: An Extended Index of Clinical Severity. Murray GD, Brennan PM, Teasdale GM J Neurosurg. 2018 April 10. [Epub ahead of print] Simplifying the Use of Prognostic Information in Traumatic Brain Injury. Part 2: Graphical Presen...
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What is the ICU Charts app? Patient care within an intensive care unit (ICU) is challenging and can lead well-intentioned critical care physicians to neglect some of the fundamental aspects of daily care. Care of the critically ill patient is often punctuated with physiologic changes that require immediate attention. Given the frequency of emergent and urgent interventions, ICU clinicians may be distracted from important, but less urgent, tasks that are still essential fo...
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Hydrocortisone plus Fludrocortisone for Adults with Septic Shock Annane D, Renault A, Brun-Buisson C, et al N Engl J Med. 2018 Mar 1; 378(9): 809-818. doi: 10.1056/NEJMoa1705716. Abstract BACKGROUND: 背景 Septic shock is characterized by dysregulation of the host response to infection, with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with hydrocortisone plus fludrocortisone or with drotrecogin alfa (activated), which can modulate the h...
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