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Drugs & Diseases > Clinical Trends Clinical Trends for May 2017 Ryan Syrek May 26, 2017 Each week, we identify one top search term, speculate as to what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, feel free to share them with us on Twitter or Facebook! Clinical Trend of the Week (May 20-26): NSAIDs Some troubling news about a popular class of drugs resulted in this week's top search...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Review ~ Alain Combes et al. The ICM research agenda on extracorporeal life support. Original ~ Jean-François Timsit et al. Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE’s STAT-Net. Original ~ Frank Bloos et al. Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomised trial....
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Recommended Reading from the University of Ottawa Nephrology Fellows David Massicotte-Azarniouch, Syed Obaid Amin, Caitlin Hesketh and Edward G. Clark AJRCCM Articles in Press. Published on 02-May-2017 as 10.1164/rccm.201611-2375RR Bitker L, et al.; Prevalence and risk factors of hypotension associated with preload-dependence during intermittent hemodialysis in critically ill patients. Crit Care (10) Reviewed by Caitlin Hesketh Intradialytic hypotension (IDH) is a common ...
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Recommended Reading from the University of Ottawa Nephrology Fellows David Massicotte-Azarniouch, Syed Obaid Amin, Caitlin Hesketh and Edward G. Clark AJRCCM Articles in Press. Published on 02-May-2017 as 10.1164/rccm.201611-2375RR Zarbock et al. Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial. JAMA (6) Reviewed by Syed Obaid Amin The Effect of Early vs...
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Recommended Reading from the University of Ottawa Nephrology Fellows David Massicotte-Azarniouch, Syed Obaid Amin, Caitlin Hesketh and Edward G. Clark AJRCCM Articles in Press. Published on 02-May-2017 as 10.1164/rccm.201611-2375RR Gaudry S, et al.; Initiation strategies for renal-replacement therapy in the intensive care unit. N Engl J Med (1) Reviewed by David Massicotte-Azarniouch Meta-analyses of mainly observational studies have shown relatively earlier initiation of...
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Effect of laminar airflow ventilation on surgical site infections: a systematic review and meta-analysis Peter Bischoff, Peter Bischoff, N Zeynep Kubilay, et al Lancet Infect Dis 2017; 17: 553-561 DOI: http://dx.doi.org/10.1016/S1473-3099(17)30059-2 Summary Background 背景 The role of the operating room's ventilation system in the prevention of surgical site infections (SSIs) is widely discussed, and existing guidelines do not reflect current evidence. In this context, ...
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ORIGINAL ARTICLE Time to Treatment and Mortality during Mandated Emergency Care for Sepsis Christopher W. Seymour, Foster Gesten, Hallie C. Prescott, et al. N Engl J Med May 21, 2017 DOI: 10.1056/NEJMoa1703058 BACKGROUND 背景 In 2013, New York began requiring hospitals to follow protocols for the early identification and treatment of sepsis. However, there is controversy about whether more rapid treatment of sepsis improves outcomes in patients. 2013年,纽约州开始要求所有...
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ORIGINAL ARTICLE Angiotensin II for the Treatment of Vasodilatory Shock Ashish Khanna, Shane W. English, Xueyuan S. Wang, et al. N Engl J Med May 21, 2017 DOI: 10.1056/NEJMoa1704154 BACKGROUND 背景 Vasodilatory shock that does not respond to high-dose vasopressors is associated with high mortality. We investigated the effectiveness of angiotensin II for the treatment of patients with this condition. 对大剂量升压药物无反应的血管舒张性休克伴随很高的病死率。我们研究了这种情...
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Research Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study Akbar K Waljee, Mary A M Rogers, Paul Lin, et al. BMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j1415 (Published 12 April 2017) Cite this as: BMJ 2017;357:j1415 Abstract Objective 背景 To determine the frequency of prescriptions for short term use of oral corticosteroids, and adverse events (sepsis, venous thromboembolism, fractures) associate...
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Abdominal Aortic Aneurysm: Has the Bubble Burst? Rick C Jiang, MBBS, BMedSc, PostGradDipSurgAnat, FRACS; Mark P Brady, PA-C | May 10, 2017 An aneurysm is defined as an increase of greater than 50% from the vessel's original size. For an abdominal aortic aneurysm (AAA), this equates to a diameter of approximately 3 cm. The larger the aneurysm, the greater the risk of rupture. AAAs are commonly diagnosed either incidentally or when they become symptomatic or rupture. Whereas...
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