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Drugs & Diseases > Clinical Trends Clinical Trends for April 2017 Ryan Syrek | April 28, 2017 Each week, we identify one top search term, speculate as to what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, feel free to share them with us on Twitter or Facebook! Clinical Trend of the Week (April 22-28): Rheumatoid Arthritis News about risk and a key drug denial resulted in this week's ...
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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Neto AS, et al. Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual pa...
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本周在线发表文章(免费阅读) ONLINE FIRST THIS WEEK (FREE ACCESS) Original ~ Emmanuelle Cambau et al. Performance and economic evaluation of the molecular detection of pathogens for patients with severe infections: the EVAMICA open-label, cluster-randomised, interventional crossover trial. Research Agenda ~ Yaseen M. Arabi et al. The intensive care medicine research agenda in nutrition and metabolism. What's New in Intensive Care ~ Antoine Schneider and Marlies Ostermann....
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Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study Yang Wang, Guo-Bao Tian, Rong Zhang, et al Lancet Infect Dis 2017; 17: 390-399 DOI: http://dx.doi.org/10.1016/S1473-3099(16)30527-8 Summary Background 背景 The mcr-1 gene confers transferable colistin resistance. mcr-1-positive Enterobacteriaceae (MCRPE) have attracted substantial medical, me...
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Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study Jingjing Quan, Xi Li, Yan Chen, et al Lancent Infect Dis 2017; 17: 400-410 DOI: http://dx.doi.org/10.1016/S1473-3099(16)30528-X Summary Background 背景 Polymyxin antibiotics are used as last-resort therapies to treat infections caused by multidrug-resistant Gram-negative bacteria. The plasmid-mediated colistin resistance dete...
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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Dickson et al. Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome. Nat Microbio (8) Reviewed by Daniel S. Jones Acute respiratory distress syndrome (ARDS) is...
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Original Investigation April 2017 Comparative Effectiveness of Vancomycin and Metronidazole for the Prevention of Recurrence and Death in Patients With Clostridium difficile Infection Vanessa W. Stevens; Richard E. Nelson; Elyse M. Schwab-Daugherty, et al JAMA Intern Med. 2017;177(4):546-553. doi:10.1001/jamainternmed.2016.9045 Abstract Importance 背景 Metronidazole hydrochloride has historically been considered first-line therapy for patients with mild to moder...
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Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority trial David C Lye, Sophia Archuleta, Sharifah F Syed-Omar, et al. Lancet DOI: http://dx.doi.org/10.1016/S0140-6736(17)30269-6 Summary Background 背景 Dengue is the commonest vector-borne infection worldwide. It is often associated with thrombocytopenia, and prophylactic platelet transfusion is...
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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Kor DJ. Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial. JAMA (1) Reviewed by Kevin C. Ma Acute respiratory distress syndr...
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Kidney Injury and Repair Biomarkers in Marathon Runners Sherry G. Mansour, Gagan Verma, Rachel W. Pata, et al. Am J Kidney Dis 2017 (Epub ahead of print) http://dx.doi.org/10.1053/j.ajkd.2017.01.045 Background: 背景 Investigation into strenuous activity and kidney function has gained interest given increasing marathon participation. 由于参加马拉松比赛的热情日增,有关剧烈运动与肾功能的研究也引发了人们的兴趣。 Study Design: 研究设计 Prospective observational study. 前瞻观察...
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