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Perspective > Society for Healthcare Epidemiology of America (SHEA) COMMENTARY Duration of Therapy and Follow-up Blood Cultures in Bacteremia: New Information Emily Spivak, MD, MHS February 08, 2018 Bloodstream Infections: Gaps in Knowledge 血行性感染:知识的空白 Gram-negative bacteremia accounts for up to half of all bloodstream infections, yet little is known about the shortest effective duration of therapy, and guideline recommendations do not exist outside of gr...
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Comment & Response March 6, 2018 Lung Recruitment and Positive End-Expiratory Pressure Titration in Patients With Acute Respiratory Distress Syndrome—Reply Alexandre Biasi Cavalcanti, Marcelo Britto Passos Amato, Carlos Roberto Ribeiro de Carvalho JAMA. 2018;319(9):934-935. doi:10.1001/jama.2017.21864 In Reply Dr McKown and colleagues suggest that the method used to personalize PEEP might be one explanation for the higher mortality in the recruitment maneuver and P...
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Special Communication March 13, 2018 Health Care Spending in the United States and Other High-Income Countries Irene Papanicolas, Liana R. Woskie, Ashish K. Jha JAMA. 2018;319(10):1024-1039. doi:10.1001/jama.2018.1150 Abstract Importance 背景 Health care spending in the United States is a major concern and is higher than in other high-income countries, but there is little evidence that efforts to reform US health care delivery have had a meaningful influence on contr...
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Original Investigation Caring for the Critically Ill Patient February 27, 2018 Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial Christopher S. Parshuram, Karen Dryden-Palmer, Catherine Farrell, et al JAMA. Published online February 27, 2018. doi:10.1001/jama.2018.0948 Abstract Importance 背景 There is limited evidence that the use of severity of illness scores in pediatric patien...
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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Letter ~ Maxime Coutrot et al. Euglycemic ketoacidosis, a common and underecognised complication of continuous renal replacement therapy using glucose-free solutions. From the Inside ~ Daniel Brodie et al. There’s more to medicine than machines. What's New in Intensive Care ~ Matthieu Schmidt et al. Have we averted deaths using venoarterial ECMO? Understanding the Disease ~ Hans Flaatten et al. Understanding card...
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Original Investigation Caring for the Critically Ill Patient February 27, 2018 Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial David M. P. van Meenen, Sophia M. van der Hoeven, Jan M. Binnekade, et al JAMA. Published online February 27, 2018. doi:10.1001/jama.2018.0949 Abstract Importance 背景 It remains uncertain whether n...
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JAMA Clinical Evidence Synopsis March 6, 2018 Procalcitonin Testing to Guide Antibiotic Therapy in Acute Upper and Lower Respiratory Tract Infections Philipp Schuetz, Yannick Wirz, Beat Mueller JAMA. 2018;319(9):925-926. doi:10.1001/jama.2018.0852 Abstract Clinical Question 临床问题 Is the use of procalcitonin for guiding antibiotic decisions in patients with acute upper and lower respiratory tract infections associated with improved clinical outcomes compared with...
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Comment & Response March 6, 2018 Lung Recruitment and Positive End-Expiratory Pressure Titration in Patients With Acute Respiratory Distress Syndrome Andrew C. McKown, Matthew W. Semler, Todd W. Rice JAMA. 2018;319(9):932-933. doi:10.1001/jama.2017.21856 To the Editor The trial by the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial (ART) Investigators1 compared a low positive end-expiratory pressure (PEEP) strategy2 with one combining a recr...
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Articles Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals Nathalie Conrad, Andrew Judge, Jenny Tran, et al Lancet 2018; 391: 572-580 Summary Background 背景 Large-scale and contemporary population-based studies of heart failure incidence are needed to inform resource planning and research prioritisation but current evidence is scarce. We aimed to assess temporal trends in incidence and prevalence of heart failur...
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Comment & Response February 13, 2018 Early Resuscitation for Adults With Sepsis in a Low-Income Country Wagner Luis Nedel, Caroline Deutschendorf JAMA. 2018;319(6):614. doi:10.1001/jama.2017.20406 To the Editor 致编辑 Dr Andrews and colleagues1 performed a randomized clinical trial of a sepsis protocol for early resuscitation involving intravenous fluids, vasopressors, and blood transfusion compared with usual care among adults with sepsis and hypotension in Zambi...
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