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Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study John G Laffey, Fabiana Madotto, Giacomo Bellani, et al. Lancet Respir Med 2017; 8: 627-638 Published: 14 June 2017 DOI: http://dx.doi.org/10.1016/S2213-2600(17)30213-8 Summary Background Little information is available about the geo-economic variations in demographics, management, and outcomes ...
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Clinical trial research in focus: rethinking trials in sepsis David Grimaldi, Jean-Louis Vincent Lancet Respir Med 2017; 8: 610-611 Published: August 2017 DOI: http://dx.doi.org/10.1016/S2213-2600(17)30268-0 Sepsis is a frequent condition, defined as life-threatening organ dysfunction associated with a severe infection.1 Over the past three decades, progress in understanding of the pathophysiology of sepsis has led to the development of a large number of potential new the...
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Fireworks Injuries: Ooh, Aah...Ouch! Nicole Cimino-Fiallos, MD | June 29, 2017 | Contributor Information Adapted images from (1) Wikimedia Commons/Fcb981 (top left), (2) Flickr/Mike Mozart (bottom left), and (3) Siemers F, Mauss KL, Liodaki E, Ottomann C, Bergmann PA, Mailander P. Eplasty. 2012;12:e33. [Open access.] PMID: 22848777, PMCID: PMC3406748.  The patient shown suffered a blast injury that embedded multiple foreign body tattoos within the eyes, eyelids, nose, and...
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The Montreux definition of neonatal ARDS: biological and clinical background behind the description of a new entity Daniele De Luca, Anton H van Kaam, David G Tingay, Sherry E Courtney, Olivier Danhaive, Virgilio P Carnielli, Luc J Zimmermann, Martin C J Kneyber, Pierre Tissieres, Joe Brierley, Giorgio Conti, Jane J Pillow, Peter C Rimensberger. Lancet Respir Med 2017; 5: 657-666 Published: 04 July 2017 DOI: http://dx.doi.org/10.1016/S2213-2600(17)30214-X  
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The Digital Doctor: Revolutionary Technologies Reshaping Healthcare John Watson | July 12, 2017 Image from Dreamstime Medicine's Technological Leap Forward Editing out disease from our genes. Using artificial intelligence to assist patient care. Treating psychiatric conditions with virtual reality. The by-product of an unprecedented period of technological development, 21st-century medicine's most promising advances may resemble science fiction, but they are very much fac...
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Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns) Martin Stocker, Wendy van Herk, Salhab el Helou, et al. Lancet 2017 Published: 12 July 2017 DOI: http://dx.doi.org/10.1016/S0140-6736(17)31444-7 Summary Background 背景 Up to 7% of term and late-preterm neonates in high-income countries receive antibiotics during the first 3 days of life because of su...
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Drugs & Diseases > Clinical Trends Clinical Trends for July 2017 Ryan Syrek July 28, 2017 Each week, we identify one top search term, speculate as to what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, feel free to share them with us on Twitter or Facebook! Clinical Trend of the Week (July 22-28): Vitiligo A potentially promising treatment for a fairly common condition is responsible f...
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【编者按】:JAMA杂志近期发表的文章显示,2011年全国去甲肾上腺素供应短缺与感染性休克患者病死率升高具有显著相关性。网站曾于4月6日介绍了该文摘要及主要结果。近日,MEDSCAPE刊登了Greg Martin的简短评论。我们在此刊出,以飨读者。 News & Perspective > Viewpoints COMMENTARY Drug Shortages and Septic Shock: Not a Good Mix Greg Martin, MD June 28, 2017 Association Between US Norepinephrine Shortage and Mortality Among Patients With Septic Shock Vail E, Gershengorn HB, Hua M, ...
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Medical News & Perspectives July 19, 2017 In Treating Sepsis, Questions About Timing and Mandates Jennifer Abbasi JAMA. Published online July 19, 2017. doi:10.1001/jama.2017.7997 In 2012, Rory Staunton, a 12-year-old boy from Queens, New York, died from sepsis after his pediatrician and an emergency department (ED) physician reportedly misinterpreted warning signs—a high fever and vomiting, but also a cut on his arm, and severe leg pain—as an intestinal illness and...
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Burning Up? A Guide to Treating Heat Illness Zina Semenovskaya, MD, FAWM; Sage Wiener, MD | June 30, 2017 | Contributor Information Image from the Bureau of Land Management – Nevada. In the above image, firefighters simulate the evacuation of a fellow firefighter suffering from heat illness. Heat illness encompasses a spectrum of disorders caused by environmental heat exposure, including minor conditions—such as heat rash, heat cramps, heat syncope, and heat exhaustion—as...
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