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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Dickson et al. Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome. Nat Microbio (8) Reviewed by Daniel S. Jones Acute respiratory distress syndrome (ARDS) is...
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Original Investigation April 2017 Comparative Effectiveness of Vancomycin and Metronidazole for the Prevention of Recurrence and Death in Patients With Clostridium difficile Infection Vanessa W. Stevens; Richard E. Nelson; Elyse M. Schwab-Daugherty, et al JAMA Intern Med. 2017;177(4):546-553. doi:10.1001/jamainternmed.2016.9045 Abstract Importance 背景 Metronidazole hydrochloride has historically been considered first-line therapy for patients with mild to moder...
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Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority trial David C Lye, Sophia Archuleta, Sharifah F Syed-Omar, et al. Lancet DOI: http://dx.doi.org/10.1016/S0140-6736(17)30269-6 Summary Background 背景 Dengue is the commonest vector-borne infection worldwide. It is often associated with thrombocytopenia, and prophylactic platelet transfusion is...
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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Kor DJ. Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial. JAMA (1) Reviewed by Kevin C. Ma Acute respiratory distress syndr...
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Kidney Injury and Repair Biomarkers in Marathon Runners Sherry G. Mansour, Gagan Verma, Rachel W. Pata, et al. Am J Kidney Dis 2017 (Epub ahead of print) http://dx.doi.org/10.1053/j.ajkd.2017.01.045 Background: 背景 Investigation into strenuous activity and kidney function has gained interest given increasing marathon participation. 由于参加马拉松比赛的热情日增,有关剧烈运动与肾功能的研究也引发了人们的兴趣。 Study Design: 研究设计 Prospective observational study. 前瞻观察...
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Medscape > Clinical Trends Clinical Trends for March 2017 Ryan Syrek |March 31, 2017 Clinical Trend of the Week (March 18-24): Pneumonia This week's top search term has an "inappropriate" cause. Two studies recently determined that inappropriate use of broad-spectrum antibiotics to treat pneumonia in children remains common. In one study, the electronic medical records of more than 10,000 children treated for pneumonia found that macrolides and other broad-spectrum anti...
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Volume Controlled Ventilation does not Prevent Injurious Inflation during Spontaneous Effort Takeshi Yoshida, Susumu Nakahashi, Maria Aparecida Miyuki Nakamura, et al Am J Respir Crit Care Med 2017 Published on 17-February-2017 as 10.1164/rccm.201610-1972OC Rationale: 背景 Spontaneous breathing during mechanical ventilation increases transpulmonary pressure and tidal volume, and worsens lung injury. Intuitively, controlling tidal volume and transpulmonary pressure might li...
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Editorial March 21, 2017 Optimizing the Settings on the Ventilator Settings: High PEEP for All? Ary Serpa Neto, Marcus J. Schultz JAMA. Published online March 21, 2017. doi:10.1001/jama.2017.2570 Mechanical ventilation is an effective life-support technique widely deployed across a variety of clinical settings in the care of many millions of patients each year worldwide. However, it is not a panacea. A central issue is that artificial ventilation works by pushing air ...
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Preliminary Communication | Caring for the Critically Ill Patient March 21, 2017 Effect of Intensive vs Moderate Alveolar Recruitment Strategies Added to Lung-Protective Ventilation on Postoperative Pulmonary Complications: A Randomized Clinical Trial Alcino Costa Leme, Ludhmila Abrahao Hajjar, Marcia S. Volpe, et al JAMA. Published online March 21, 2017. doi:10.1001/jama.2017.2297 Abstract Importance 背景 Perioperative lung-protective ventilation has been recommende...
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Original Investigation | Caring for the Critically Ill Patient March 21, 2017 Association Between US Norepinephrine Shortage and Mortality Among Patients With Septic Shock Emily Vail, Hayley B. Gershengorn, May Hua, et al JAMA. Published online March 21, 2017. doi:10.1001/jama.2017.2841 Abstract Importance 背景 Drug shortages in the United States are common, but their effect on patient care and outcomes has rarely been reported. 在美国,药品短缺非常普遍,但其对于患者...
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