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ORIGINAL ARTICLE A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest Gavin D. Perkins, Chen Ji, Charles D. Deakin, et al N Engl J Med July 18, 2018 DOI: 10.1056/NEJMoa1806842 BACKGROUND 背景 Concern about the use of epinephrine as a treatment for out-of-hospital cardiac arrest led the International Liaison Committee on Resuscitation to call for a placebo-controlled trial to determine whether the use of epinephrine is safe and effective in such patients. 人...
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Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study Samir K Saha, Stephanie J Schrag, Shams El Arifeen, et al. Lancet 2018; 392: 145-159 Summary Background 背景 More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. We investigated the incidence of community-acquired infections caused by specific orga...
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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) Editorial ~ Martin J. Tobin. Conflicts of interest and the patient–doctor covenant. Letter ~ Lama H. Nazer - Critical care research in the World Health Organisation Eastern Mediterranean Region over two decades: where do we stand? Editorial Debate ~ John A. Myburgh. Intracranial pressure thresholds in severe traumatic brain injury: Pro. Editorial Debate ~ Raimund Helbok et al. Intracranial pressure thresholds in ...
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Is Routine Chest X-Ray After Ultrasound-Guided Central Venous Catheter Insertion Choosing Wisely?: A Population-Based Retrospective Study of 6,875 Patients Jason Chui, Rasha Saeed, Luke Jakobowski, et al Chest 2018; 154: 148-156 Background 背景 A routine chest radiograph (CXR) is recommended as a screening test after central venous catheter (CVC) insertion. The goal of this study was to assess the value of a routine postprocedural CXR in the era of ultrasound-guided CVC...
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Antibiotic decisions in the ICU: a dragon’s tale Pieter Depuydt, MD, PhD Head of Clinic - Department of Intensive Care Ghent University Hospital Ghent, Belgium Associate Professor - Department of Internal Medicine Faculty of Medicine Ghent University consider the clinical problem of suspected infection in your ICU patient as a ‘monster’ … with a ‘head’, a ‘body’ and a ‘tail’ Medical decision-making about antibiotic use in critically ill patients is challenging and comple...
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The Burden of Viruses in Pneumonia Associated With Acute Respiratory Failure: An Underappreciated Issue Andrew F. Shorr, Kristen Fisher, Scott T. Micek, et al Chest 2018; 154: 84-90 Background 背景 Pneumonia associated with mechanical ventilation (MV) results in substantial mortality and represents a leading reason for the use of antibiotics. The role of viruses in this setting is unclear. Identifying a viral cause in such instances could facilitate antibiotic stewardsh...
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Algorithm for early diagnosis and treatment of thrombocytopaenia in ICU Patients in the intensive care unit (ICU) have a range of clinical problems, including multi-organ failure, sepsis, and shock, and early diagnosis and management are crucial to optimise outcomes. A report in the journal Critical Care proposes a new algorithm to help intensivists make a rapid diagnosis so that they can initiate early appropriate management for ICU patients with thrombocytopaenia. The...
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JAMA Clinical Guidelines Synopsis July 3, 2018 Management of Patients With Acute Lower Gastrointestinal Tract Bleeding Neil Sengupta, Adam S. Cifu JAMA. 2018;320(1):86-87. doi:10.1001/jama.2018.5684 Guideline title 指南题目 ACG Clinical Guideline: Management of Patients With Acute Lower Gastrointestinal Bleeding ACG临床指南:急性下消化道出血患者的诊治 Release date 发布日期 March 1, 2016 2016年3月1日 Funding source 资助来源 American College of Gastroenterology (ACG), Na...
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Does Size Matter When Calculating the “Correct” Tidal Volume for Pediatric Mechanical Ventilation?: A Hypothesis Based on FVC Gina J. Kim, Christopher J.L. Newth, Robinder G. Khemani, et al Chest 2018; 154: 77-83 Background 背景 Tidal volumes standardized to predicted body weight are recommended for adult mechanical ventilation, but children are frequently ventilated by using measured body weight. The goal of this study was to examine the difference in FVC (in milliliter...
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Intensive Care Medicine ONLINE FIRST (FREE ACCESS) From the Inside ~ Nicola Petrucci et al. Beyond bleeps and alarms: live music by the bedside in the ICU. Systematic Review ~ Sarah Vollam et al. Out-of-hours discharge from intensive care, in-hospital mortality and intensive care readmission rates: a systematic review and meta-analysis. Understanding the Disease ~ Pierre Tattevin et al. Understanding central nervous system efficacy of antimicrobials. Original ~ Daniel E. F...
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