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News > Medscape Medical News > Conference News > ATS 2018 Discharge From a Crowded Hospital Ward Ups Readmission Risk Ingrid Hein May 21, 2018 Patients discharged from crowded hospital wards are more likely to be readmitted to the hospital in the subsequent 30 days, new data show. The three strongest predictors of a patient's readmission "are all modifiable, ward-level factors," said lead researcher Rachel Kohn, MD, from the University of Pennsylvania in Philad...
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Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial Nikola Sprigg, Katie Flaherty, Jason P Appleton, et al. Lancet  Published: 16 May 2018 DOI: https://doi.org/10.1016/S0140-6736(18)31033-X Summary Background Tranexamic acid can prevent death due to bleeding after trauma and post-partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and ...
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News > Medscape Medical News Add-on Vasopressin May Lower AF Risk in Distributive Shock Patrice Wendling May 14, 2018 Patients in distributive shock appear to have a lower risk for atrial fibrillation when vasopressin is added to catecholamine vasopressors, but its effect on other outcomes are mixed, according to a new systematic review and meta-analysis. Based on pooled data from 13 studies at low risk of bias, the addition of vasopressin was associated with a 33% r...
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Perspective > Medscape Neurology > Viewpoints COMMENTARY Additions to Glasgow Coma Scale Aid Prognosis in TBI Laurie Barclay, MD May 15, 2018 Simplifying the Use of Prognostic Information in Traumatic Brain Injury. Part 1: The GCS-Pupils Score: An Extended Index of Clinical Severity. Murray GD, Brennan PM, Teasdale GM J Neurosurg. 2018 April 10. [Epub ahead of print] Simplifying the Use of Prognostic Information in Traumatic Brain Injury. Part 2: Graphical Presen...
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What is the ICU Charts app? Patient care within an intensive care unit (ICU) is challenging and can lead well-intentioned critical care physicians to neglect some of the fundamental aspects of daily care. Care of the critically ill patient is often punctuated with physiologic changes that require immediate attention. Given the frequency of emergent and urgent interventions, ICU clinicians may be distracted from important, but less urgent, tasks that are still essential fo...
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Hydrocortisone plus Fludrocortisone for Adults with Septic Shock Annane D, Renault A, Brun-Buisson C, et al N Engl J Med. 2018 Mar 1; 378(9): 809-818. doi: 10.1056/NEJMoa1705716. Abstract BACKGROUND: 背景 Septic shock is characterized by dysregulation of the host response to infection, with circulatory, cellular, and metabolic abnormalities. We hypothesized that therapy with hydrocortisone plus fludrocortisone or with drotrecogin alfa (activated), which can modulate the h...
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News > Reuters Health Information Restricting Fluids During Abdominal Surgery Shows No Benefit, Possible Renal Risk By Gene Emery May 11, 2018 (Reuters Health) - In a discovery that goes against emerging surgical wisdom, a new study suggests that restricting intravenous fluids before major abdominal surgery not only fails to make the operation safer for higher-risk patients, it may cause short-term kidney injury. 一项新的研究结果提示,腹部大手术前限制静脉液体不仅无法...
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ORIGINAL ARTICLE Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome Alain Combes, David Hajage, Gilles Capellier, et al N Engl J Med 2018; 378:1965-1975 DOI: 10.1056/NEJMoa1800385 Abstract BACKGROUND 背景 The efficacy of venovenous extracorporeal membrane oxygenation (ECMO) in patients with severe acute respiratory distress syndrome (ARDS) remains controversial. vvECMO对严重ARDS患者的疗效仍存在争议。 METHODS 方法 In an international clinical...
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Intensive Care Medicine ONLINE FIRST THIS WEEK (FREE ACCESS) The Surviving Sepsis Campaign (SSC) has released a new updated Hour-1 Bundle to reflect the latest evidence from the International Guidelines for Management of Sepsis and Septic Shock 2016. In this revision of the SSC bundles, the 3-hour and 6-hour bundles have been combined into a single “Hour-1 Bundle” with the explicit intention of beginning resuscitation and management immediately. This new sepsis “Hour-1 Bun...
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邀请您参加MOSAICS II研究   您还记得MOSAICS研究吗? 2009年7月,亚洲16个国家150个ICU参加了为期一个月的MOSAICS研究。研究旨在了解亚洲国家ICU中全身性感染集束化治疗的依从性及其对临床预后的影响。研究最终纳入1285名严重全身性感染/感染性休克患者,住院病死率44.5%,6小时及24小时集束化治疗措施的依从性分别为7.6%与3.5%。 该研究结果发表在BMJ 2011; 342: d3245 MOSAICS II研究的目的 Sepsis 3.0定义系根据西方高收入国家临床资料提出。而世界其他地区全身性感染流行病学特点知之甚少。 本研究主要...
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