JAMA Diagnostic Test Interpretation | July 19, 2016 Evaluation of New-Onset Ascites Yuval A. Patel, Andrew J. Muir. JAMA. 2016;316(3):340-341. doi:10.1001/jama.2016.7600. A white woman in her 60s with undifferentiated connective tissue disease and long-standing pulmonary arterial hypertension presented for evaluation of new-onset ascites. The patient reported no alcohol or drug use and no personal or family history of liver disease. Medications included diltiazem and furos...

Medscape > Case Challenges A 30-Year-Old Woman With Lower Abdominal Pain D. Brady Pregerson, MD June 15, 2016 Background 背景 A 30-year-old woman with no significant medical history presents to the emergency department with intermittent nonradiating pain in the lower left part of her abdomen. The pain started approximately 5 days ago and has been steadily worsening since then. She has also been having fever. 一名既往健康的30岁女性患者因间断非放射性左下腹疼痛到急诊就诊。...

Medscape > Fast Five Quizzes Quiz: What Do You Know About the Syndrome of Inappropriate Antidiuretic Hormone Secretion? Vecihi Batuman, MD June 03, 2016 The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hyponatremia in hospitalized patients. The prognosis of SIADH correlates with the underlying cause and the effects of severe hyponatremia and its overzealous correction. Rapid and complete recovery tends to be the ...

Hidden Heart Disease: 17 Dermatologic Clues You Should Know Rashid M Rashid, MD, PhD; Brittany Sambrano Barros, MD    |  June 16, 2016 Patients with cardiac diseases often present with manifestations on the skin. The patient in the above image, for example, has lupus pernio, a cutaneous sign of the multisystem inflammatory disease sarcoidosis. Cutaneous manifestations such as this can play a valuable role in guiding physicians to the correct cardiac diagnosis. Review our ...

Medscape > Fast Five Quizzes Quiz: What Do You Know About the Syndrome of Inappropriate Antidiuretic Hormone Secretion? Vecihi Batuman, MD June 03, 2016 The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hyponatremia in hospitalized patients. The prognosis of SIADH correlates with the underlying cause and the effects of severe hyponatremia and its overzealous correction. Rapid and complete recovery tends to be the ...

JAMA Diagnostic Test Interpretation | May 24/31, 2016 Elevated Hemoglobin or Hematocrit Level Robyn M. Scherber, MD, MPH; Ruben A. Mesa, MD JAMA. 2016;315(20):2225-2226. doi:10.1001/jama.2016.2435. A 71-year-old woman presented for evaluation of an elevated hemoglobin level (16.2 g/dL) that was incidentally discovered during a recent emergency department visit. She reported night sweats and some excessive fatigue over the last few months. She was unaware of any family his...

JAMA Diagnostic Test Interpretation | May 24/31, 2016 Elevated Hemoglobin or Hematocrit Level Robyn M. Scherber, MD, MPH; Ruben A. Mesa, MD JAMA. 2016;315(20):2225-2226. doi:10.1001/jama.2016.2435. A 71-year-old woman presented for evaluation of an elevated hemoglobin level (16.2 g/dL) that was incidentally discovered during a recent emergency department visit. She reported night sweats and some excessive fatigue over the last few months. She was unaware of any family his...

JAMA Diagnostic Test Interpretation HbA1c in the Evaluation of Diabetes Mellitus Derek T. O'Keeffe, MB, BCh, BAO, PhD; Spyridoula Maraka, MD; Robert A. Rizza, MD JAMA 2016; 315: 605-606 A 76-year-old man presented to his physician's office, requesting assistance managing his type 2 diabetes. He was diagnosed 18 months previously, based on a fasting blood glucose level of 200 mg/dL (11 mmol/L), and was prescribed metformin. The metformin was discontinued 12 months later...

JAMA Diagnostic Test Interpretation HbA1c in the Evaluation of Diabetes Mellitus Derek T. O'Keeffe, MB, BCh, BAO, PhD; Spyridoula Maraka, MD; Robert A. Rizza, MD JAMA 2016; 315: 605-606 A 76-year-old man presented to his physician's office, requesting assistance managing his type 2 diabetes. He was diagnosed 18 months previously, based on a fasting blood glucose level of 200 mg/dL (11 mmol/L), and was prescribed metformin. The metformin was discontinued 12 months l...

Medscape > Fast Five Quizzes Quiz: Are You Able to Confront Clostridium Difficile Infections? Michael Stuart Bronze, MD January 04, 2016 Clostridium difficile is a gram-positive, anaerobic, spore-forming bacillus that is responsible for the development of antibiotic-associated diarrhea and colitis. C difficile infection commonly manifests as mild to moderate diarrhea, occasionally with abdominal cramping. In rare cases, patients with C difficile infection can present w...