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The 50 Most Influential Physicians in History, Part 1: #50-#36 Steven Rourke  |  February 5, 2016 Compiling a ranking of the most influential physicians throughout history is a perilous undertaking that has fueled animated discussions between Medscape editors and advisors. Influence is a tricky thing to gauge, after all, and depends entirely on one's viewpoint, background, location, and specialty. And "history" is a rather long timeframe. Some prickly questions were raised...
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Physical Manifestations of 8 Drugs of Abuse Michael J. Payette, MD, MBA  |  February 2, 2016 Anabolic Steroids Anabolic steroids, also referred to as "Arnolds," "juice," and "roids," are synthetically produced variants of testosterone.[1,3] Their clinical use has been for hormone replacement therapy and for illness-related cachexia.[22] As drugs of abuse, anabolic steroids are used as performance enhancing agents—for promoting muscle growth, enhancing athletic and/or sexu...
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Physical Manifestations of 8 Drugs of Abuse Michael J. Payette, MD, MBA  |  February 2, 2016 Discussion of substance abuse generally revolves around addiction, with a focus on the neurologic, psychosocial, and medicolegal consequences of this disorder. It is known that most drugs of abuse can alter a person's thinking and judgment, as well as lead to health risks that include addiction, drugged driving, and infectious disease.[1,2] One important issue that may not be cons...
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Ten old antibiotics that will never disappear. Matteo Bassetti, Matthew E. Falagas, Marin Kollef. Intensive Care Med DOI 10.1007/s00134-015-3705-5 抗生素耐药问题在世界范围内令人担忧且日益严重。仅有极少数新的抗生素进入药物研发过程,同时在很多国家,有些老的药物尽管属于基本药物,却由于缺乏利润或管理结构新的要求等其他原因,逐渐从市场上消失或暂时无法供应。但是,哪些抗生素目前仍很有帮助而且永远也不会消失呢?我们相信,多粘菌素、磷霉素、氨基糖甙、万古霉素、利福平、苯唑西林、头孢...
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Can Deaths From Acute Kidney Injury Be Eliminated Worldwide? CME/CE News Author: Diedtra Henderson CME Author: Charles P. Vega, MD CME/CE Released: 05/21/2015 ; Valid for credit through 05/21/2016 临床背景 全球每年约有13,300,000人罹患急性肾损伤(AKI),其中约有85%的患者在发展中国家。根据社会经济状况不同,AKI的临床表现也显著不同。富裕国家中AKI主要见于医院内。总体而言,每5名成年住院患者及每3名住院患儿中分别有1人发生AKI,ICU中AKI的比例更高。在高收入国家的一项AKI研究发现,ICU中...
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(CNN) MERS-CoV是中东呼吸综合征冠状病毒的缩写,于2012年春季在沙特阿拉伯最早发现。 根据WHO报告,时至6月8日,25个国家共确诊超过1000例MERS患者。全球死亡病例超过400例。 以下是有关MERS你需要了解的5个事实: MERS属于冠状病毒 MERS与SARS病毒属于同一种病毒。SARS于2003年导致超过8000人感染,全球死亡773例,与此不同,MERS在人群之间并不容易传播—至少现在还是如此。 CDC指出,MERS-CoV感染与感冒相似,累及呼吸系统。但是临床症状(包括发热和咳嗽)更为严重,可导致肺炎和肾功能衰竭。WHO报告,也可...
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[编者按]:5月21日,MEDSCAPE网站发布了有关AKI流行病学的继续教育内容。我们首先将课后考试题目呈现给大家,随后再发布正文,以便同道们有目的的阅读理解。 Q1 你正在访视一名有乏力及少尿病史的65岁女性患者。患者有糖尿病和高血压病史,但很少就医。患者2天前因腹痛入院后接受CT扫描。实验室检查提示可能为AKI。有关全球AKI的流行病学情况,你的认识如何? You are seeing a 65-year-old woman with a history of fatigue and oliguria. She has a history of diabetes and hypertension with poor medical fo...
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The ten diseases that look like ARDS 与ARDS表现相似的十种疾病   Claude Guérin, Taylor Thompson, Roy Brower Intensive Care Med DOI 10.1007/s00134-014-3608-x   Introduction Five decades ago, Ashbaugh and colleagues first used the term ‘‘syndrome of acute respiratory distress’’ (ARDS) to describe 12 patients with respiratory failure [1]. The hallmarks of the syndrome were hypoxemia refractory to supplemental oxygen, diffuse radiographic opacities, and histologic evi...
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Medical News & Perspectives | May 12, 2015 Everything You Ever Wanted to Know About Evidence-based Medicine Rebecca Voelker, MSJ JAMA. 2015;313(18):1783-1785. doi:10.1001/jama.2015.2845. Gordon Guyatt, MD, MSc, McMaster University 循证医学意味着什么?问问Gordon Guyatt医生。25年前Guyatt开始担任加拿大安大略省Hamilton的McMaster大学内科主任,他希望教会住院医生如何在医学文献中发现最佳临床证据,如何正确解读,并用之于患者。“在当时,这是非常新 的想法,” 他说到。 为在加拿...
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[编者按]:在过去十年间,循证医学一直是临床医生关注的焦点。有人对它奉若神明,也有人对它不屑一顾。2015年5月12日,JAMA发表了对循证医学最初的倡导者,加拿大多伦多McMaster大学Gordon Guyatt医生的访谈。让我们看看他对于循证医学的理解。不久我们还将发布本文的中文译文。 Medical News & Perspectives | May 12, 2015 Everything You Ever Wanted to Know About Evidence-based Medicine Rebecca Voelker, MSJ JAMA. 2015;313(18):1783-1785. doi:10.1001/jama.2015.2845. Gordon Guyatt, MD, MSc, M...
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